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Chick embryo infections for the evaluation of anticoccidial drugs

Published online by Cambridge University Press:  06 April 2009

J. F. Ryley
J. F. Ryley
Affiliation:
Imperial Chemical Industries Ltd., Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire
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Extract

Chick embryos have been infected with sporozoites of Eimeria tenella, but not with E. brunetti, and died from coccidiosis 5 days after infection.

Chick embryos can be protected from death due to coccidiosis by some but not all drugs which give a therapeutic response in chickens. The system is therefore not satisfactory as a screening tool, but may have applications in studies on the nature of drug activity.

Type
Research Article
Information
Parasitology , Volume 58 , Issue 1 , February 1968 , pp. 215 - 220
Copyright
Copyright © Cambridge University Press 1968

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References

REFERENCES

Long, P. L. (1965). Development of Eimeria tenella in avain embryos. Nature, Lond. 208, 509–10.CrossRefGoogle Scholar
Long, P. L. (1966). The growth of some species of Eimeria in avain embryos. Parasitology 56, 575–81.CrossRefGoogle Scholar
Patton, W. H. (1965). Eimeria tenella: cultivation of the asexual stages in cultured animal cells. Science 150, 767–9.CrossRefGoogle ScholarPubMed
Ryley, J. F. (1967). Methyl benzoquate, a new wide-spectrum coccidiostat for chickens. Br. Vet. J. 123, 513–20.CrossRefGoogle ScholarPubMed
Spencer, C. F., Engle, A., Yu, C., Finch, R. C., Watson, E. J., Ebetino, F. F. & Johnson, C. A. (1966). Anticoccidial activity in a series of alkyl 6, 7-dialkoxy-4-hydroxy-3-quino-linecarboxylates. J. Med. Chem. 9, 934–6.CrossRefGoogle Scholar
Stock, B. L., Stevenson, G. T. & Hymas, T. A. (1967). Coyden coccidiostat for control of coccidiosis in chickens. Poult. Sci. 46, 485–92.CrossRefGoogle Scholar
Wagner, W. H. & Foerster, O. (1964). Die PAS-AO-Methode, eine Spezialfärbung für Coccidien im Gewebe. Z. ParasitKde. 25, 28–48.CrossRefGoogle Scholar