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Characterization of the lipid content of Toxoplasma gondii rhoptries

Published online by Cambridge University Press:  06 April 2009

F. Foussard ,
M. A. Leriche  and
J. F. Dubremetz
F. Foussard
Affiliation:
Laboratoire de Biochimie Médicale, rue Haute de Reculée, 49000 Angers
M. A. Leriche
Affiliation:
Unité 42 INSERM, 369, rue J Guesde, 59650 Villeneuve d' Ascq, France
J. F. Dubremetz
Affiliation:
Unité 42 INSERM, 369, rue J Guesde, 59650 Villeneuve d' Ascq, France
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Extract

Quantitative and qualitative analysis of lipids has been performed on a rhoptry fraction purified from Toxoplasma gondii tachyzoites. The lipid to protein ratio was estimated to be 0·26. The cholesterol to phospholipid ratio was unusually high at 1·48. Phosphatidylcholine was the major phospholipid; phosphatidylserine, phosphatidylinositol and sphingomyelin were absent whereas significant amounts of phosphatidic acid and lysophospholipids were found. This pelicular composition could be related to functional involvement of the organelle in host-cell invasion.

Keywords

Toxoplasma gondiilipidsrhoptry
Type
Research Article
Information
Parasitology , Volume 102 , Issue 3 , June 1991 , pp. 367 - 370
Copyright
Copyright © Cambridge University Press 1991

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