Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-10T03:02:12.555Z Has data issue: false hasContentIssue false
  • English
  • Français

Cellular immune response of Drosophila melanogaster against Asobara tabida

Published online by Cambridge University Press:  08 November 2011

A. J. Nappi
A. J. Nappi
Affiliation:
Department of Biology, Loyola University, Chicago, Illinois 60626
Get access Rights & Permissions [Opens in a new window]

Summary

The successful cellular immune response of larvae of D. melanogaster against A. tabida is characterized by an increase in the number of blood cells, a premature transformation of spherical plasmatocytes to flattened, disc-shaped lamellocytes, and the lysis of crystal cells. The plasmatocytes and transformed lamellocytes rapidly aggregate around the eggs of the parasite to form a cellular capsule, while the lysing crystal cells release substances causing the melanization of the capsule. The early appearance of large numbers of transformed blood cells in the haemolymph prior to their involvement in capsule formation suggests that transformation is independent of cell contact with the parasite and may be due instead to biochemical stimuli emitted from the parasite and/or by hormonal changes. Quantitative blood cell studies of hosts exhibiting no encapsulation and melanization response indicate that successfully developing parasites are recognized by the immune system but are able sufficiently to block the blood cell transformation and thus prevent capsule formation.

Type
Research Article
Information
Parasitology , Volume 83 , Issue 2 , October 1981 , pp. 319 - 324
Copyright
Copyright © Cambridge University Press 1981

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Lackie, A. M. (1980). Invertebrate immunity. Parasitology 80, 393–412.Google Scholar
Nappi, A. J. (1970). Hemocytes of larvae of Drosophila euronotus (Diptera: Drosophilidae) Annals of the Entomological Society of America 62, 1217–24.Google Scholar
Nappi, A. J. (1974). Insect hemocytes and the problem of host recognition of foreignness. In Contemporary Topics in Immunobiology, vol. 4 (ed. Cooper, E. L.), pp. 207–224. New York: Plenum Press.Google Scholar
Nappi, A. J. (1975a). Cellular immune reactions of larvae of Drosophila algonquin. Parasitology 70, 189–94.Google Scholar
Nappi, A. J. (1975b). Parasite encapsulation in insects. In Invertebrate Immunity. Mechanisms of Invertebrate Vector-Parasite Relations, (ed. Maramorosch, K. and Shope, R. E.), pp. 293–325. New York and London: Academic Press.Google Scholar
Nappi, A. J. (1977). Immune response to Drosophila rnelanogaster against Asobara tabida. Journal of Parasitology Suppl. (Abstract) p. 68.Google Scholar
Nappi, A. J. (1978). Immune reactions of invertebrates to foreign materials. In Animal Models of Comparative and Developmental Aspects of Immunity and Disease, (ed. Gershwin, M. E. and Cooper, E. L.), pp. 15–24. New York: Pergamon Press.Google Scholar
Nappi, A. J. & Streams, F. A. (1969). Haemocytic reactions of Drosophila rnelanogaster to the parasites Pseudeucoila mellipes and P. bochei. Journal of Insect Physiology 15, 1551–66.CrossRefGoogle Scholar
Rizki, M. T. (1957). Alterations in the hemocyte population of Drosophila rnelanogaster. Journal of Morphology 100, 459–72.Google Scholar
Rizki, M. T. & Rizki, R. M. (1959). Functional significance of the crystal cells in the larva of Drosophila rnelanogaster. Journal of Biophysical and Biochemical Cytology 5, 235–40.Google Scholar
Salt, G. (1970). Cellular Defence Reactions of Insects. Cambridge University Press.CrossRefGoogle Scholar
Walker, I. (1959). Die Abwehrreaktion des Wirtes Drosophila rnelanogaster gegen die zoophage Cynipidae Pseudeucoila bochei Weld. Revue Suisse Zoologie 69, 569–632.Google Scholar