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The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis – Corrigendum

Published online by Cambridge University Press:  09 June 2017

A. Q. I. ALQAISI ,
A. J. MBEKEANI ,
M. BASSAS LLORENS ,
A. P. ELHAMMER  and
P. W. DENNY
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Abstract

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Type
Corrigendum
Information
Parasitology , Volume 145 , Special Issue 2: Microbial protein targets: towards understanding and intervention , February 2018 , pp. 156
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Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © Cambridge University Press 2017

The authors apologise for errors which appear in the legend of Figure 2. Please find below the corrected legend.

Fig. 2. ED50 of Aureobasidin A (AbA, A-D) or Compound 20 (Cpmd 20, E-H) – µg mL−1; (95% Confidence Interval) – against the Toxoplasma RH tachyzoite form in HFF cells. 6 days post addition of the compounds. In agreement with Sonda et al. (2005), both compounds were non-toxic to HHF cells under the conditions employed. A and E: no wash out post-compound addition; B and F: wash out 2 h post-compound addition; C and G: wash out 8 h post-compound addition; D and H: 2 h pre-treatment of isolated parasites pre-infection. Calculated using GraphPad Prism 7, log (inhibitor) vs normalized response – Variable slope. >10 µg mL−1 – ED50 could not be determined. Representative in triplicate dataset.

References

REFERENCE

Alqaisi, A. Q. I., Mbekeani, A. J., Bassas Llorens, M., Elhammer, A. P. and Denny, P. W. (2017). The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis. Parasitology. Published by Cambridge University Press, 10 May 2017. doi: 10.1017/S0031182017000506.Google Scholar