Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-30T23:41:30.108Z Has data issue: false hasContentIssue false
  • English
  • Français

Survival, strobilation and sexual maturation of Echinococcus multilocularis in the small intestine of golden hamsters

Published online by Cambridge University Press:  06 April 2009

M. Kamiya  and
H. Sato
M. Kamiya
Affiliation:
Department of Parasitology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060, Japan
H. Sato
Affiliation:
Department of Parasitology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo 060, Japan
Get access Rights & Permissions [Opens in a new window]

Summary

Echinococcus multilocularis survived, strobilated and matured sexually in the small intestine of 6-week-old male golden hamsters that were either non-treated or treated with prednisolone tertiary-butylacetate (PTBA), following oral administration of 20000 protoscoleces. Non-treated hamsters harboured the adult worms for up to 25 days post-infection (p.i.). Hamsters treated with PTBA from the day of infection (day 0 p.i.) harboured more adults than the non-treated, and their survival periods were extended. Moreover, a remarkable improvement in worm recovery, development and survival periods was observed in hamsters additionally treated with PTBA on days — 14 and — 12 p.i., and the worm development including proglottisation, sexual maturation and egg formation was comparable with that in dogs. With the present results it is suggested that Echinococcus/rodent systems represented by the E. multilocularis/golden hamsters may rejuvenate the current stagnant research on host-parasite interactions of the definitive host-stage and egg-stage of Echinococcus.

Keywords

Echinococcus multilocularisgolden hamstersprednisolonealternative definitive hostexperimental model
Type
Research Article
Information
Parasitology , Volume 100 , Issue 1 , February 1990 , pp. 125 - 130
Copyright
Copyright © Cambridge University Press 1990

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Arme, C. (1987). Cestoda. In In Vitro Methods for Parasite Cultivation (ed. Taylor, A. E. R. & Baker, J.), pp. 282–317. London: Academic Press.Google Scholar
Berberian, D. A. (1936). Some observations on the effect of digestive juices on scolices of Echinococcus granulosus (Batsch). Journal of Helminthology 14, 21–40.Google Scholar
Gnezdilov, V. G. (1957). The golden hamster (Mesocricetus auratus Waterhouse) as a potential definitive host of the tape worm Taenia solium. Zoological Journal 36, 1770–3. (In Russian with English summary).Google Scholar
Herd, R. P. (1977). Resistance of dogs to Echinococcus granulosus. International Journal for Parasitology 7, 135–8.Google Scholar
Herd, R. P., Ko, L., Weisbrode, S. E. & Heath, D. D. (1984). Sequential morphologic changes in adult Echinococcus granulosus during complement-mediated lysis in vitro. International Journal for Parasitology 14, 141–9.Google Scholar
Ito, A. & Smyth, J. D. (1987). Adult cestodes; immunology of the lumen-dwelling cestode infections. In Immune Responses in Parasitic Infections: Immunology, Immunopathology and Immunoprophylaxis, Vol. 2 (ed. Soulsby, E. J. L.), pp. 115–63. Florida: CRC Press.Google Scholar
Kamiya, H. (1974). Susceptibility of golden hamsters to infection with larval Echinococcus multilocularis. Japanese Journal of Veterinary Science 36, 99–109. (In Japanese with English summary.)Google ScholarPubMed
Kamiya, M., Oku, Y., Kamiya, H. & Nomura, T. (1982). Characteristic responses of nude mice in angiostrongyliasis and echinococcosis. In Proceedings of the Third International Workshop on Nude Mice (ed. Reed, N. D.), pp. 133–145. New York: Gustav Fischer.Google Scholar
Kamiya, M., Ooi, H. K. & Ohbayashi, M. (1986). Susceptibility of cats to the Hokkaido isolate of Echinococcus multilocularis. Japanese Journal of Veterinary Science 48, 763–7.Google Scholar
Kamiya, M., Ooi, H. K., Oku, Y., Okamoto, M., Ohbayashi, M. & Seki, N. (1987). Isolation of Echinococcus multilocularisfrom the liver of swine in Hokkaido, Japan. Japanese Journal of Veterinary Research 35, 99–107.Google Scholar
Kitaoka, M. (1988). Golden hamsters as a definitive host of Taenia crassiceps (Cestoda). Japanese Journal of Veterinary Research 36, 159.Google Scholar
Kovalenko, F. P. (1976). Survival of Echinococcus multilocularis and E. granulosus protoscoleces in the intestine of laboratory rodents. Meditsinskaya Parazitologiya i Parazitarnye Bolezni 45, 350–2. (In Russian with English summary.)Google Scholar
Kroeze, W. K. & Freeman, R. S. (1983). Growth and development of Taenia crassiceps (Cestoda) in the small intestine and peritoneal cavity of mice following oral infection. Canadian Journal of Zoology 61, 1598–604.Google Scholar
Kumaratilake, L. M. & Thompson, R. C. A. (1981). Maintenance of the life cycle of Echinococcus granulosus in the laboratory following in vivo and in vitro development. Zeitschrift für Parasitenkunde 65, 103–6.CrossRefGoogle ScholarPubMed
Kumaratilake, L. M., Thompson, R. C. A., Eckert, J. & 'Alessandro, A. D. (1986). Sperm transfer in Echinococcus (Cestoda: Taeniidae). Zeitschift für Parasitenkunde 72, 265–9.CrossRefGoogle ScholarPubMed
Pathak, K. M. L. & Gaur, S. N. S. (1985). Effect of immunosuppressants and antihistaminics on the development of Taenia solium in golden hamsters. Indian Journal of Veterinary Medicine 5, 10–12.Google Scholar
Rausch, R. L. (1973). Significado taonxómico de algunas características de la especie Echinococcus. Boletín de Hidatidosis 3, 7–10.Google Scholar
Rausch, R. L. (1985). Parasitology: retrospect and prospect. Journal of Parasitology 71, 139–51.Google Scholar
Sato, H. & Kamiya, M. (1989). Viable egg production of Taenia crassiceps developed in the intestine of prednisolone-treated golden hamsters. Japanese Journal of Parasitology 38, 46–53.Google Scholar
Smyth, J. D. (1962). Lysis of Echinococcus granulosus by surface-active agents in bile and the role of this phenomenon in determining host specificity in helminths. Proceedings of the Royal Society, B 156, 553–72.Google Scholar
Smyth, J. D. (1967). Studies on tapeworm physiology. XI. In vitro cultivation of Echinococcus granulosus from the protoscolex to the strobilate stage. Parasitology 57, 111–33.CrossRefGoogle Scholar
Smyth, J. D. (1968). In vitro studies and host-specificity in Echinococcus. Bulletin of the World Health Organization 39, 5–12.Google ScholarPubMed
Smyth, J. D. (1979). Echinococcus granulosus and E. multilocularis; in vitro culture of the strobilar stages from protoscoleces. Angewandte Parasitologie 20, 137–47.Google Scholar
Smyth, J. C. & Davies, C. J. (1979). In vitro differentiation of Echinococcus as a taxonomic tool, with special reference to its use in ‘strain’ identification. Helminthologia 16, 5–12.Google Scholar
Smyth, J. D. & Davies, Z. (1974). In vitro culture of the strobilar stage of Echinococcus granulosus (sheep strain): A review of basic problems and results. International Journal for Parasitology 4, 631–44.Google Scholar
Smyth, J. D. & Davies, Z. (1975). In vitro suppression of segmentation in Echinococcus multilocularis with morphological transformation of protoscoleces into monozoic adults. Parasitology 71, 125–35.Google Scholar
Smyth, J. D. & Haslewood, G. A. D. (1963). The biochemistry of bile as a factor in determining host specificity in intestinal parasites, with particular reference to Echinococcus granulosus. Annals of the New York Academy of Sciences 113, 234–60.Google Scholar
Smyth, J. D. & Howkins, A. B. (1966). An in vitro technique for the production of eggs of Echinococcus granulosus by maturation of partly developed strobila. Parasitology 56, 763-6.CrossRefGoogle Scholar
Smyth, J. D., Howkins, A. B. & Barton, M. (1966). Factors controlling the differentiation of the hydatid organism, Echinococcus granulosus, into cystic or strobilar stages in vitro. Nature, London 211, 1374–7.Google Scholar
Smyth, J. D., Miller, H. J. & Howkins, A. B. (1967). Further analysis of the factors controlling strobilization, differentiation, and the maturation of Echinococcus granulosus in vitro. Experimental Parasitology 21, 31–41.Google Scholar
Smyth, J. D. & Smyth, M. M. (1964). Natural and experimental hosts of Echinococcus granulosus and E. multilocularis with comments on the genetics of speciation in the genus Echinococcus. Parasitology 54, 493–514.CrossRefGoogle Scholar
Smyth, J. D. & Smyth, M. M. (1968). Some aspects of host specificity in Echinococcus granulosus. Helminthologia 9, 519–28.Google Scholar
Smyth, J. D. & Smyth, M. M. (1969). Self insemination in Echinococcus granulosus in vivo. Journal of Helminthology 43, 383–8.Google Scholar
Thompson, R. C. A. (1986). Biology and systematics of Echinococcus. In The Biology of Echinococcus and Hydatid Disease (ed. Thompson, R. C. A.), pp. 5–43. London: George Allen & Unwin Ltd.Google Scholar
Thompson, R. C. A. & Eckert, J. (1982). The production of eggs by Echinococcus multilocularis in the laboratory following in vivo and in vitro development. Zeitschrift für Parasitenkunde 68, 227–34.Google Scholar
Thompson, R. C. A. & Lymbery, A. J. (1988). The nature, extent and significance of variation within the genus Echinococcus. In Advances in Parasitology, Vol. 27 (ed. Baker, J. R. & Muller, R.), pp. 209–58. London: Academic Press.Google Scholar
Thompson, R. C. A. & Smyth, J. D. (1976). Attempted infections of the rhesus monkey (Macaca mulatto) with the British horse strain of Echinococcus granulosus. Journal of Helminthology 50, 175–7.CrossRefGoogle Scholar
Verster, A. (1971). Preliminary reports on the golden hamster as a definitive host of Taenia solium Linnaeus, 1758 and Taenia saginata Goeze, 1782. Onderstepoort Journal of Veterinary Research 38, 63–4.Google Scholar
Verster, A. (1974). The golden hamster as a definitive host of Taenia solium and Taenia saginata.Onderstepoort Journal of Veterinary Research 41, 23–8Google ScholarPubMed