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Epidemiological review of toxoplasmosis in humans and animals in Romania

Published online by Cambridge University Press:  29 October 2013

J. P. DUBEY*
Affiliation:
United States Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal Parasitic Diseases Laboratory, Building 1001, BARC-East, Beltsville, MD 20705-2350, USA
I. HOTEA*
Affiliation:
Department of Parasitology, Faculty of Veterinary Medicine, Banat's University of Agricultural Sciences and Veterinary Medicine, 119, Aradului Street, 300645 Timisoara, Timis, Romania
T. R. OLARIU
Affiliation:
Department of Parasitology, Victor Babes University of Medicine and Pharmacy, P-ta Murgu Eftimie, 2, 300041 Timisoara, Timis, Romania
J. L. JONES
Affiliation:
Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Building 24, 1600 Clifton Road, NE, Mailstop A-06, Atlanta, GA30333, USA
G. DĂRĂBUŞ
Affiliation:
Department of Parasitology, Faculty of Veterinary Medicine, Banat's University of Agricultural Sciences and Veterinary Medicine, 119, Aradului Street, 300645 Timisoara, Timis, Romania
*
*Corresponding authors: USDA, ARS, APDL, BARC-East, Building 1001, Beltsville, MD 20705, USA. E-mail: [email protected]
USAMVB Timisoara, 119, Aradului Street, 300645, Timisoara, Romania. E-mail: [email protected]

Summary

Infections by the protozoan parasite Toxoplasma gondii are widely prevalent in humans and other animals worldwide. However, information from eastern European countries is sketchy. In many eastern European countries, including Romania, it has been assumed that chronic T. gondii infection is a common cause of infertility and abortion. For this reason, many women in Romania with these problems were needlessly tested for T. gondii infection. Most papers on toxoplasmosis in Romania were published in Romanian in local journals and often not available to scientists in other countries. Currently, the rate of congenital infection in Romania is largely unknown. In addition, there is little information on genetic characteristics of T. gondii or prevalence in animals and humans in Romania. In the present paper we review prevalence, clinical spectrum and epidemiology of T. gondii in humans and animals in Romania. This knowledge should be useful to biologists, public health workers, veterinarians and physicians.

Type
Research Article
Creative Commons
This is a work of the U.S. Government and is not subject to copyright protection in the United States.
Copyright
Copyright © Cambridge University Press 2013

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References

*Antoniu, S., Moldoveanu, D. and Ionescu, V. (2005). Anthropozoonotical aspects in toxoplasmosis. Revista Romana de Medicina Veterinara 15, 135140.Google Scholar
*Antoniu, S., Ştirbu-Teofănescu, B. and Militaru, D. (2007). The paraclinical diagnosis of toxoplasmosis in cats. Revista Romana de Parazitologie 17, 1518.Google Scholar
*Antoniu, S., Teofănescu, B. Ş., Militaru, D. and Căpitanu, G. (2008). Feline toxoplasmosis diagnosis using indirect immunofluorescence reaction and ELISA. Revista Romana de Medicina Veterinara 18, 250254.Google Scholar
Balea, A., Pastiu, A. I., Györke, A., Mircean, V. and Cozma, V. (2012). The dynamics of anti-Toxoplasma gondii antibodies in small ruminants and pigs from Cluj County, Romania. Scientia Parasitologica 13, 163168.Google Scholar
*Barabás-Hajdu, E., Miklós, A., Miklós, T. and Simó, A. (2007). Serodiagnostics of toxoplasmosis in Mures County Hospital's Central Laboratory in 2000–2005. Revista Romana de Parazitologie 17, 3336.Google Scholar
*Boer, C. L., Iacobiciu, I., Olariu, R. T., Marţincu, C., Gheorghiu, E. and Macovievici, G. (2002). Considerations on the immunodiagnostic value of the AxSYM Toxo IgM and IgG assay for the detection of specific anti-Toxoplasma gondii antibodies. Revista Romana de Parazitologie 12, 5355.Google Scholar
*Bondoc, I., Asiminei, S. and Antoci, R. (2007). Immunoenzymatic study regarding the incidence of toxoplasmosis at some species of animals. Revista Romana de Parazitologie 17, 1922.Google Scholar
*Cambrea, S. C., Ilie, M., Cambrea, M., Ionescu, V. and Rugină, S. (2007). Cerebral toxoplasmosis in seropositive teenagers. Revista Romana de Parazitologie 17, 8993.Google Scholar
*Chitjmia, L., Nălbaru, A. M., Banu, T., Apostu, C. and Constantinoiu, C. (2011). Seroprevalence of ovine toxoplasmosis by indirect immunofluorescence test. Revista Romana de Medicina Veterinara 21, 136141.Google Scholar
*Codarcea, M., Gorun, E., Rugină, S., Muja, E., Ilie, M. and Neagu, M. (2000). Toxoplasmic encephalitis in the settings of AIDS. Revista Romana de Parazitologie 10, 5153.Google Scholar
*Codarcea, M., Blebea, E., Basca, E., Dumea, E., Cernat, R. and Rugină, C. (2007). Cerebral toxoplasmosis in HIV/AIDS patients; two case presentations. Revista Romana de Parazitologie 17, 9597.Google Scholar
Codreanu, R. R. and Rădulescu, S. (2007). Clinical and therapeutical aspects in ganglionary toxoplasmosis. Revista Romana de Parazitologie 17, 5966.Google Scholar
*Colţan, G., Marin, C. and Rebedea, I. (2000). Cerebral toxoplasmosis – difficulties of diagnosis and treatment (case presented). Revista Romana de Parazitologie 10, 4850.Google Scholar
Coroiu, Z., Radu, R., Molnar, A. and Bele, J. (2009). Seroprevalence of anti Toxoplasma gondii antibodies in the healthy population from north-western and central Romania. Scientia Parasitologica 1, 3742.Google Scholar
Costache, C., Junie, M. and Coroiu, Z. (2004). Toxoplasmosis in Cluj county. Scientia Parasitologica 5, 5053.Google Scholar
Costache, C., Colosi, I. and Junie, M. (2008 a). The importance of anti-Toxoplasma Ig A detection in newborns. Congress: European Multicolloquium of Parasitology, France 10, 4347.Google Scholar
Costache, C. A., Tigan, S. I., Colosi, I. and Coroiu, Z. (2008 b). Toxoplasmic infection in pregnant women from Cluj County and neighbouring area. Applications in Medical Informatics 23, 3136.Google Scholar
Costache, C. A., Colosi, I. and Junie, M. (2010). Testing for toxoplasmic immunity in women of fertile age – are we prepared? Scientia Parasitologica 11, 4446.Google Scholar
Costache, C. A., Colosi, H. A., Blaga, L., Györke, A., Pastiu, A. I., Colosi, I. A. and Ajzenberg, D. (2013). First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania. Parasite 20, 11.CrossRefGoogle ScholarPubMed
*Cozma, V., Şuteu, O., Titilincu, A. and Osztian, R. M. (2007). Seroprevalence of Toxoplasma gondii antibodies in dogs from Cluj-Napoca. Revista Romana de Parazitologie 17, 2326.Google Scholar
Creţu, C., Cilievici, S., Neagu, R., Voinea, L. and Corbu, C. (2007). Is ocular toxoplasmosis an important health problem in Romania? Revista Romana de Parazitologie 17, 8184.Google Scholar
Creţu, C. M., Rădulescu, S., Ristea, L. F., Pop de Popa, D., Tacorian, D., Voinea, L., Mihăilescu, P. and Popă, L. (2000). Ocular toxoplasmosis: clinical, diagnosis and therapeutics aspects. Revista Romana de Parazitologie 10, 5051.Google Scholar
*Crucerescu, E. (1998). Epidemiological data on toxoplasmosis. The aspects of congenital toxoplasmosis. Bacteriology, Virusology, Parazitology and Epidemiology 43, 147155.Google Scholar
Crucerescu, E. and Lovin, D. (2001). Toxoplasmosis risk in eastern Romania. Jurnal de Medicina Preventiva 9, 5460.Google Scholar
Crucerescu, E. and Lovin, D. (2002). Study on specific IgG avidity as a tool for recent primary Toxoplasma gondii infection diagnosis. Jurnal de Medicina Preventiva 10, 5662.Google Scholar
Csep, A. (2010 a). Epidemiological and clinico-biological correlations in the diagnosis of achieved toxoplasmosis. Analele Universitatii din Oradea 10, 247254.Google Scholar
Csep, A. (2010 b). Aspects of toxoplasmosis diagnosis in women at the procreation age and pregnant women. Analele Universitatii din Oradea 10, 261268.Google Scholar
Csep, A. (2010 c). Clinico-biological aspects in congenital toxoplasmosis. Analele Universitatii din Oradea 10, 255260.Google Scholar
Dărăbuş, Gh., Afrenie, M., Olariu, R. T., Ilie, M. S., Balint, A. and Hotea, I. (2011 a). Epidemiological remarks on Toxoplasma gondii infection in Timisoara Zoo. Scientia Parasitologica 12, 3337.Google Scholar
Dărăbuş, Gh., Hotea, I., Oprescu, I., Morariu, S., Brudiu, I. and Olariu, R. T. (2011 b). Toxoplasmosis seroprevalence in cats and sheep from Western Romania. Revue de Medicine Veterinaire 162, 316320.Google Scholar
*Dogan, D. and Farah, C. (2004). Clinical and serologic research in toxoplasmic uveitis in children. Oftalmologia 48, 5563.Google Scholar
*Dragomir, C. (1956). Isolation on the animal (white mice) of a strain of Toxoplasma from a case of human toxoplasmosis. Microbiology, Parasitology and Epidemiology 4, 1826.Google Scholar
Dubey, J. P. (2010). Toxoplasmosis of Animals and Humans, 2nd Edn. CRC Press, Boca Raton, FL, USA.Google Scholar
Dubey, J. P. and Beattie, C. P. (1988). Toxoplasmosis of Animals and Man. CRC Press, Boca Raton, FL, USA.Google Scholar
*Dumitru, I., Rugină, S. and Rugină, C. (2007). Toxoplasmosis with hepatitis and lymphadenopathy – case presentation. Revista Romana de Parazitologie 17, 6769.Google Scholar
Elias, M. I. (1966). Beitrage zur Epidemiologie der Toxoplasmose. Zeitschrift fur Tropenmedizin und Parasitologie 17, 8799.Google Scholar
*Elias, M. I. and Budiu, T. (1973). Human and Animal Toxoplasmosis. Edtura Facla, Timisoara.Google Scholar
*Elias, M. I. and Porsche, T. (1961). Serological research on the incidence of toxoplasmosis in apparently healthy people. Microbiology (Bucharest) 6, 155159.Google Scholar
*Elias, M. I. and Pucă-Ciudin, M. (1967). Research on the effectiveness of diagnostic methods in toxoplasmosis. Microbiologia, Parazitologia, Epidemiologia 12, 6772.Google ScholarPubMed
*Elias, M. I., Gluhovschi, N., Pucă-Ciudin, M. and Costin, P. (1963 a). Observations on a focus of ovine toxoplasmosis. Microbiologia, Parazitologia, Epidemiologia 8, 133137.Google Scholar
*Elias, M. I., Pucă-Ciudin, M., Costin, P., Porshe, T., Borbil, I. and Bogdan, F. (1963 b). Clinical and epidemiological aspects of congenital toxoplasmosis. Microbiologia, Parazitologia, Epidemiologia 8, 127131.Google Scholar
Erscoiu, S., Ungureanu, E., Alecu, D., Ionescu, C. and Mihăilă, L. (2007). Clinical and therapeutical aspects of cerebral toxoplasmosis in Romanian AIDS patients. Revista Romana de Parazitologie 17, 108109.Google Scholar
Georgescu, G., Tudor, P., Tudor, N., Grosu, F. and Ionescu, A. (2009). A clinical case of toxoplasmic encephalitis in a cat. Scientific Works C series Veterinary Medicine, Bucuresti 55, 222225.Google Scholar
*Georgescu, M. (1976). Structural aspects at the individual level in the epidemiological process in human toxoplasmosis. Bacteriology, Virusology, Parazitology, Epidemiology and Pneumophysiology 21, 105110.Google ScholarPubMed
Gheoca, D., Hărânglăvean, A. and Gheoca, V. (2009). Aspects of Toxoplasma. Toxoplasma-like parasitism in small mammal species in Transylvania and their role in Toxoplasma dissemination. Studia Universitatis Vasile Goldis Arad 19, 6973.Google Scholar
*Ghinea, M., Niculescu, Z. and Nicoară, A. (2007). On inflammatory adenopathies diagnosis. Revista Romana de Parazitologie 17, 5558.Google Scholar
Györke, A., Opsteegh, M., Mircean, V., Iovu, A. and Cozma, V. (2011). Toxoplasma gondii in Romanian household cats: evaluation of serological tests, epidemiology and risk factors. Preventive Veterinary Medicine 102, 321328.Google Scholar
Hotea, I., Dărăbuş, Gh., Ilie, M. S., Imre, K., Ciocan, R., Balint, A., Indre, D. and Măndiţă, D. (2009 a). The prevalence of Toxoplasma gondii infection in cats from Hunedoara County. Scientific Works C Series Veterinary Medicine Bucuresti 55, 312319.Google Scholar
*Hotea, I., Dărăbuş, Gh., Ilie, M. S., Imre, K., Oprescu, I., Morariu, S. and Mederle, N. (2009 b). The identification of Toxoplasma gondii infection in sheep from Arad County. Lucrări ştiinţifice Medicină Veterinară Timisoara 42, 1621.Google Scholar
Hotea, I., Dărăbuş, Gh., Mederle, N., Ilie, M. S., Imre, K., Balint, A. and Indre, D. (2009 c). The prevalence of Toxoplasma gondii infection in cats in Arad County. Lucrări ştiinţifice Medicină Veterinară, Iasi 52, 587592.Google Scholar
Hotea, I., Dărăbuş, Gh., Ilie, M. S., Imre, K., Balint, A., Indre, D., Imre, M., Sorescu, D., Ciocan, R., Costinar, L. and Pascu, C. (2010 a). Seroprevalence of Toxoplasma gondii infection in pigs reared in intensive system from Timis County. Lucrări ştiinţifice Medicină Veterinară Timişoara 43, 6872.Google Scholar
Hotea, I., Dărăbuş, Gh., Ilie, M. S., Imre, K., Balint, A., Indre, D., Imre, M., Sorescu, D. and Ciocan, R. (2010 b). Preliminary study of toxoplasmic infection in domestic pigs from Timis County. Scientific Works C Series Veterinary Medicine Bucuresti 56, 5358.Google Scholar
Hotea, I., Dărăbuş, Gh., Păcurar, C., Rugea, T., Muntean, P., Ilie, M. S., Imre, K., Imre, M., Sorescu, D., Balint, A. and Indre, D. (2010 c). Preliminary study on the prevalence of Toxoplasma gondii infection in wild boars from Timis County. Lucrări ştiinţifice Medicină Veterinară, Iasi 53, 7073.Google Scholar
Hotea, I., Ilie, M. S., Imre, M., Sorescu, D. and Dărăbuş, Gh. (2011 a). Determining of toxoplasmosis seroprevalence, by ELISA, in lambs in Timis County. Lucrări ştiinţifice Medicină Veterinară, Iasi 54, 161164.Google Scholar
Hotea, I., Oprescu, I., Ilie, M. S., Imre, K. and Dărăbuş, Gh. (2011 b). Seroprevalence of Toxoplasma gondii infection, by ELISA, in rams in Timis County. Lucrări ştiinţifice Medicină Veterinară, Iasi 54, 325328.Google Scholar
Hotea, I., Oprescu, I., Sorescu, D., Ciocan, R. and Dărăbuş, Gh. (2011 c). Toxoplasmosis seroprevalence in pigs from Arad County. Lucrări ştiinţifice Medicină Veterinară Timişoara 44, 5862.Google Scholar
Hotea, I., Ilie, M. S., Imre, M., Sorescu, D., Indre, D., Brudiu, I., Colibar, O. and Dărăbuş, Gh. (2012). Toxoplasma gondii seroprevalence in cats and sheep from Caras-Severin County, Romania. Lucrări ştiinţifice Medicină Veterinară, Iasi 55, 104109.Google Scholar
Iovu, A., Titilincu, A., Mircean, V., Blaga, R., Bejan, A. and Cozma, V. (2008 a). Serosurvey of Toxoplasma gondii in sheep for human consumption in two slaughter-houses. Bulletin UASVM Veterinary Medicine 65, 4043.Google Scholar
*Iovu, A., Titilincu, A., Mircean, V., Blaga, R. and Cozma, V. (2008 b). Preliminary results regarding the seroprevalence of Toxoplasma gondii infection in pigs from intensive farming. Scientia Parasitologica 2, 2125.Google Scholar
*Iovu, A., Traversa, D., Milillo, M., Titilincu, A. and Cozma, V. (2008 c). A quantitative PCR method to determine the Toxoplasma gondii infection in the tissues of abortion sheep. Revista Romana de Parazitologie 18, 111.Google Scholar
Iovu, A., Titilincu, A., Mircean, V., Blaga, R., Voinescu, V. and Cozma, V. (2009). Seroprevalence of Toxoplasma gondii infection in indoor pigs from Center and North-Western of Romania. Bulletin UASVM Veterinary Medicine 66, 103107.Google Scholar
Iovu, A. I., Titilincu, A., Voinescu, V. and Cozma, V. (2010). Molecular investigation of sow abortions for the detection of Toxoplasma gondii and Hammondia hammondi. Scientia Parasitologica 11, 101104.Google Scholar
Iovu, A., Györke, A., Mircean, V., Gavrea, R. and Cozma, V. (2012). Seroprevalence of Toxoplasma gondii and Neospora caninum in dairy goats from Romania. Veterinary Parasitology 186, 470474.Google Scholar
*Junie, M. and Coroiu, Z. (1995). Incidence and consequences of acute Toxoplasma gondii infection in pregnancy evolution. Obstetrica si Ginecologia 43, 4548.Google Scholar
Junie, M., Coroiu, Z., Costache, C. and Stranţ, M. (2000). Toxoplasmic congenital malformations. Revista Romana de Parazitologie 10, 4447.Google Scholar
Junie, M., Coroiu, Z., Mihalache, M. and Costache, C. (2002). The medical human importances of the toxoplasmic infection acquired during pregnancies. Scientia Parasitologica 2, 6266.Google Scholar
*Jurja, S. (2007). Toxoplasmic necrotizing retinitis – clinical case. Revista Romana de Parazitologie 17, 8587.Google Scholar
Lazăr, L. and Barbu, I. (2007). Fetal and placental abnormalities with neurological and ocular sequelae during congenital toxoplasmosis. Revista Romana de Parazitologie 17, 106107.Google Scholar
Lazăr, L., Radu-Niculescu, M., Ştefănescu, A. and Agârbiceanu, I. (2002). Profile of ocular toxoplasmosis within retinouveal pathology: clinical and evolutive post chemotherapy outcome. Revista Romana de Parazitologie 12, 5152.Google Scholar
*Lupaşcu, G., Bossie-Agavriloaei, A., Atanasiu, M., Dahnovici, V., Burnuz, M., Elias, M. I. and Pucă-Ciudin, M. (1963). Contribution to the study of human toxoplasmosis. Investigation of several different groups of the population with the toxoplasmin intradermoreaction. Microbiology, Parasitology and Epidemiology 9, 119126.Google Scholar
*Marcaş, C., Cambrea, C., Ilie, M. and Rugină, S. (2007). Cerebral toxoplasmosis evolution in HIV infected adolescent – case presentation. Revista Romana de Parazitologie 17, 99102.Google Scholar
Mării, C., Iancu, M., Miu, N., Zaharie, G., Samașcă, G. and Idrizi, E. (2008). Primary and secondary care of congenital infection with Toxoplasma gondii . Applications in Medical Informatics 22, 2126.Google Scholar
Mederle, N., Dărăbuş, Gh., Oprescu, I., Morariu, S., Ilie, M. S., Imre, K., Hotea, I. and Mederle, O. (2008). Correlation between histological, serological and epidemiological investigations in human toxoplasmosis. Lucrari Stiintifice Medicina Veterinara Timisoara 41, 355360.Google Scholar
Medrea, V. and Constantinescu, V. (1991). Untersuchungen zur Diagnose der Toxoplasma gondii-Infecktion beim Wiederkäuer. Monatshefte für Veterinärmedizin 46, 467468.Google Scholar
Mello, U. (1910). Un cas de toxoplasmose du chien observé à Turin (2). Bulletin de la Société de Pathologie Exotique 3, 359363.Google Scholar
*Mihai, M., Marinov, B., Munteanu, L. and Condruz, E. (1976). Evolution of immunity to Toxoplasma gondii in an apparently healthy human population. Bacteriology, Virusology, Parazitology, Epidemiology and Pneumophysiology 21, 155158.Google Scholar
*Mihai, M., Marinov, R., Baciu, G., Rener, L., Vinătoru, E., Blum, L., Chirculescu, O., Tirziman, I., Pricop, M., Gilcă, M. and Gilcă, D. (1978). Prospective evaluation of the risk of congenital toxoplasmosis. II. Further data on the immune response during pregnancy. Bacteriology, Virusology, Parasitology and Epidemiology 23, 147151.Google Scholar
Militaru, D., Ştirbu-Teofănescu, B., Militaru, M. and Ciobotaru, E. (2008). Serological detection of anti-Toxoplasma gondii antibodies in abattoir slaughtered pigs and sheep. Revista Romana de Parazitologie 18, 145.Google Scholar
Mircean, V., Titilincu, A. and Cozma, V. (2010). Prevalence of endoparasites in household cat (Felis catus) populations from Transylvania (Romania) and association with risk factors. Veterinary Parasitology 171, 163166.CrossRefGoogle ScholarPubMed
Navolan, D. B., Ciohat, I. M., Tigla, A. E., Vasies, D. and Dumitrascu, V. (2012). Risk assessment for TORCH complex infection agents during pregnancy – preliminary study. Timisoara Medical Journal 62, 1519.Google Scholar
Neagoe, I., Gherman, R., Rădulescu, A., Pop, M., Bucurenci, N., Dumitrache, A. and Steriu, D. (2007). Determination of a possible congenital toxoplasmosis by detection specific antigens (NTP-hydrolase) with monoclonal antibodies in pregnant women with seroconversion. Revista Romana de Parazitologie 17, 4347.Google Scholar
Nicolle, C. and Manceaux, L. (1908). Sur une infection à corps de Leishman (ou organismes voisins) du gondi. Comptes Rendus des Séances de l'Academie des Sciences 147, 763766.Google Scholar
Nicolle, C. and Manceaux, L. (1909). Sur un protozoaire nouveau du gondi. Comptes Rendus des Séances de l'Academie des Sciences 148, 369372.Google Scholar
Olariu, T. R., Dărăbuş, Gh., Creţu, O., Jurovits, O., Giura, E., Erdelean, V., Marincu, I., Iacobiciu, I., Petrescu, C. and Koreck, A. (2008). Prevalence of Toxoplasma gondii antibodies among women of childbearing age in Timis County. Lucrări Stiintifice Medicină Veterinară Timisoara 41, 367371.Google Scholar
Oprea, C., Ungureanu, E., Rădoi, R., Ene, L., Tardei, G., Tetradov, S., Cigoianu, R. and Duiculescu, D. (2007). Atovaquone, an alternative therapeutic regimen in cerebral toxoplasmosis in HIV-1 infected children. Revista Romana de Parazitologie 17, 114115.Google Scholar
Opsteegh, M., Haveman, R., Swart, A. N., Mensink-Beerepoot, M. E., Hofhuis, A., Langelaar, M. F. M. and van der Giessen, J. W. B. (2012). Seroprevalence and risk factors for Toxoplasma gondii infection in domestic cats in the Netherlands. Preventive Veterinary Medicine 104, 317326.Google Scholar
Panaitescu, D., Steriu, D., Proca-Cioban, M., Ştefănoiu, V., Silard, R. and Potcoavă, R. (1978). Studies concerning the assessment of the incidence of human toxoplasmosis. Archives Roumaine of Pathology and Experimental Microbiology 37, 399405.Google Scholar
Panaitescu, D., Căpraru, T. and Bugarin, V. (1995 a). Study of the incidence of intestinal and systemic parasitoses in a group of children with handicaps. Roumaine Archive of Microbiology and Immunology 54, 6574.Google Scholar
Panaitescu, D., Steriu, D., Ştefănoiu, V. and Pop, M. (1995 b). Research on congenital toxoplasmosis. Roumaine Archive of Microbiology and Immunology 54, 313324.Google Scholar
Păstârnac, N. (2009). Toxoplasmosis in mink (Mustela vison). Revista Romana de Medicina Veterinara 19, 8295.Google Scholar
Paștiu, A. I., Györke, A., Blaga, R., Mircean, V., Rosenthal, B. M. and Cozma, V. (2013). In Romania, exposure to Toxoplasma gondii occurs twice as often in swine raised for familial consumption as in hunted wild boar, but occurs rarely if ever among fattening pigs raised in confinement. Parasitology Research 112, 24032407.Google Scholar
Petriceanu, G., Guţu, E., Rădulescu, R. A., Ragalie, A. and Tănăsuică, R. (2007). The prevalence of serological diagnosed toxoplasmosis cases in animals from Romania between 2006 and 2007 years. Institutul de Diagnostic si Sanatate Animala Bucuresti 1, 114.Google Scholar
Pop, A., Cerbu, A., Pop, A. and Andreescu, N. (1986). The seasonal prevalence of Toxoplasma gondii infections in stray cats from urban areas, studied by parasitological methods. Archives Roumaine of Pathology and Experimental Microbiology 45, 5763.Google Scholar
Pop, A., Oprişan, A., Pop, A., Cerbu, A., Stavarache, M. and Niţu, R. (1989). Toxoplasmosis prevalence parasitologicaly evaluated in meat animals. Archives Roumaine of Pathology and Experimental Microbiology 48, 373378.Google Scholar
Proca-Cioban, M., Ştefănoiu, V., Potcoavă, R., Panaitescu, D. and Steriu, D. (1981). Incidence of anti-Toxoplasma antibodies in children with neurological manifestations and ocular diseases. Archives Roumaine of Pathology and Experimental Microbiology 40, 9199.Google Scholar
Radacovici, E. and Atanasiu, M. (1959). Contributions to the study of human toxoplasmosis in our country. Microbiology, Parasitology and Epidemiology 4, 329335.Google Scholar
Radbea, N., Mederle, O., Barbu, D. and Izvernariu, D. (2006). Human corioretinitis with Toxoplasma gondii – a case report. Lucrari Stiintifice Medicina Veterinara Timisoara 39, 1921.Google Scholar
Rugină, S., Dumitru, I. and Gorun, E. (2007). Toxoplasmosis in pregnant women. Revista Romana de Parazitologie 17, 7175.Google Scholar
Sabin, A. B. and Feldman, H. A. (1948). Dyes as microchemical indicators of a new immunity phenomenon affecting a protozoon parasite (Toxoplasma). Science 108, 660663.Google Scholar
Sharma, S. P. (1980). Prevalence of Toxoplasma infection in sheep in Romania. Veterinary Parasitology 7, 1923.Google Scholar
*Siloşi, I., Rogoz, S., Siloşi, C., Rogoz, I., Avramescu, C. and Badea, P. (2006). Immune serological evaluation in toxoplasmosis. Revista Romana de Parazitologie 16, 2326.Google Scholar
*Siloşi, I., Ungureanu, A., Rogoz, S., Siloşi, C., Avramescu, C., Muşetescu, A., Drackoulogona, O. and Neamţu, C. (2007). Immunoserological investigations in toxoplasmosis. Revista Romana de Parazitologie 17, 4953.Google Scholar
Splendore, A. (1908). Un nuovo protozoo parassita de conigli incontrato nelle lesioni anatomiche d'una malattia che ricorda in molti punti il Kala-azar dell’ uomo. Nota preliminare. Revista da Sociedade Scientífica de São Paulo. 3, 109112.Google Scholar
*Ştefănoiu, V., Panaitescu, D., Steriu, D. and Proca Ciobanu, M. (1983). Incidence of anti-Toxoplasma antibodies in patients with lymph node reactions. Bacteriology, Virusology, Parasitology and Epidemiology 28, 371376.Google Scholar
*Ştirbu-Teofănescu, B., Amzuţa, A., Comârzan, A. M. and Militaru, D. (2005). Researches concerning the ovine toxoplasmosis serodiagnosis by ELISA. Lucrari Stiintifice Medicina Veterinara Timisoara 38, 647652.Google Scholar
*Ştirbu-Teofănescu, B., Militaru, D., Militaru, M. and Diaconu, I. (2008). Surveillance of porcine toxoplasmosis through IgG type antibodies detection by immunoenzymatic test. Lucrari Stiintifice Medicina Veterinara, Iasi 51, 950952.Google Scholar
*Stroia, V. and Ungureanu, A. (2007). Congenital toxoplasmosis. Revista Romana de Parazitologie 17, 7780.Google Scholar
Teodorescu, C., Steriu, D., Teodorescu, I., Miclos, M. and Pop, M. (2006). Cases of cerebral hydatidosis, cysticercosis and toxoplasmosis in Romania. Revista Romana de Parazitologie 16, 2732.Google Scholar
*Teodorescu, C., Manea, V. and Teodorescu, I. (2007). Toxoplasma gondii diagnosis in pregnant women by PCR and ELISA technics. Revista Romana de Parazitologie 17, 3741.Google Scholar
Teodorescu, C., Teodorescu, I., Raneti, C., Dumitrica, D. M. and Ştefan, C. (2008). The anti-Toxoplasma gondii antibodies incidence to the different ocular diseases patients cases of human ocular toxoplasmosis infections in Romania. Oftalmologia 52, 8894.Google Scholar
*Titilincu, A., Blaga, R., Halos, L., Mircean, V., Boireau, P. and Cozma, V. (2008 a). Diagnosis of Toxoplasma gondii infection in sheep by ELISA and MAT. Scientia Parasitologica 2, 1520.Google Scholar
*Titilincu, A., Mircean, V., Blaga, R., Chiţimia, L., Cernea, M., Mirescu, F. and Cozma, V. (2008 b). Research regarding the prevalence of Toxoplasma gondii infection in cats. Revista Romana de Medicina Veterinara 18, 108122.Google Scholar
Titilincu, A., Mircean, V. and Cozma, V. (2008 c). Seroprevalence of Toxoplasma gondii infection in goats from centre and north-west of Romania. Lucrări ştiinţifice Medicină Veterinară, Iaşi 51, 544547.Google Scholar
Titilincu, A., Mircean, V., Iovu, A. and Cozma, V. (2009). Development of an indirect ELISA test using tachyzoite crude antigen for sero-diagnosis of sheep Toxoplasma gondii infection. Bulletin UASVM Veterinary Medicine 66, 137141.Google Scholar
Toma, R., Guguianu, E., Busuioc, C., Stoicescu, A., Tisu, A. and Toma, V. (1967 ). Epidemiological aspects of toxoplasmosis in the city of Bucharest. I. Brief investigations on the incidence of toxoplasmosis among certain categories of suspected and exposed populations. Microbiology, Parasitology and Epidemiology 12, 5966.Google Scholar
Turcitu, M. A., Pricop, L., Cioranu, R., Bărbuceanu, F., Diaconu, C., Banu, T., Chiţimia, L., Codreanu, M. D., Codreanu, I. and Antoniu, S. (2012). Incidence of Toxoplasma gondii in sheep in Romania. Preliminary results. Revista Romana de Medicina Veterinara 22, 112117.Google Scholar
Wolf, A., Cowen, D. and Paige, B. (1939). Human toxoplasmosis: occurrence in infants as an encephalomyelitis verification by transmission to animals. Science 89, 226227.CrossRefGoogle ScholarPubMed
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