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Comparison of single and split-dose flubendazole treatment for the nematode parasite Trichostrongylus tenuis in experimentally infected grey partridges Perdix perdix

Published online by Cambridge University Press:  31 July 2012

D. PURDY ,
N. J. AEBISCHER  and
C. DAVIS
D. PURDY
Affiliation:
Game & Wildlife Conservation Trust, Burgate Manor, Fordingbridge, Hants SP6 1EF, UK
N. J. AEBISCHER*
Affiliation:
Game & Wildlife Conservation Trust, Burgate Manor, Fordingbridge, Hants SP6 1EF, UK
C. DAVIS
Affiliation:
Game & Wildlife Conservation Trust, Burgate Manor, Fordingbridge, Hants SP6 1EF, UK
*
*Corresponding author: Tel: 01425 652381. Fax: 01425 655848. E-mail: [email protected]
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Summary

Different therapeutic regimes using flubendazole for the treatment of Trichostrongylus tenuis infection in experimentally infected grey partridges Perdix perdix were examined. Flubendazole dosages of 4, 8 and 20 mg/kg were administered orally as a single dose or split into 3 or 9 parts given over 9 days. The efficacy against adult worms in the caeca improved with dose rate. Split doses were at least as effective as single doses, which removed up to 83% of adult T. tenuis. A dose of 20 mg/kg administered on a daily basis over 3 or 9 days gave the best clearance of T. tenuis, resulting in a reduction of at least 95% in worm burden.

Keywords

Lagopus lagopus scoticusPerdix perdixTrichostrongylus tenuisflubendazole
Type
Research Article
Information
Parasitology , Volume 139 , Issue 13 , November 2012 , pp. 1780 - 1783
Copyright
Copyright © Cambridge University Press 2012

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