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Absence of potentiation between quinine and pyrimethamine in infections of Plasmodium gallinaceum in chicks

Published online by Cambridge University Press:  06 April 2009

Ann Bishop
Ann Bishop
Affiliation:
Molteno Institute, University of Cambridge
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Extract

The effect of combined doses of pyrimethamine and quinine has been studied in P. gallinaceum. No potentiation of the action of the drugs was observed.

Type
Research Article
Information
Parasitology , Volume 46 , Issue 1-2 , May 1956 , pp. 220 - 223
Copyright
Copyright © Cambridge University Press 1956

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References

REFERENCES

Bishop, A. (1954). The action of 2:4-diamino-6:7-diisopropylpteridine upon Plasmodium gallinaceum and its relation to other compounds which are pteroylglutamic acid antagonists. Parasitology, 44, 450.CrossRefGoogle Scholar
Bishop, A. & McConnachie, E. W. (1950). Sulphadiazine-resistance in Plasmodium gallinaceum and its relation to other antimalarial compounds. Parasitology, 40, 163.CrossRefGoogle ScholarPubMed
Bishop, A. & McConnachie, E. W. (1952). Pamaquin resistance in a strain of Plasmodium gallinaceum and its relationship to other antimalarial drugs. Parasitology, 42, 57.CrossRefGoogle Scholar
Greenberg, J. (1949). The potentiation of the antimalarial activity of chlorguanide by p–aminobenzoic acid competitors. J. Pharmacol. 97, 238.Google ScholarPubMed
Greenberg, J. (1953). Reversal of the activity of chlorguanide against Plasmodium gallinaceum by free or conjugated p–aminobenzoie acid. Exp. Parasitol. 2, 271.CrossRefGoogle Scholar
Ray, A. P., Misra, B. G., Chandrasekhar, G. R. & Singh, J. (1953). Screening of antimalarials against P. gallinaceum in chicks. Part III. Synergistic action of pyrimethamine and quinine. Indian J. Malarial. 7, 311.Google Scholar
Reilly, J., Chen, G. & Geiling, E. M. K. (1950). The action of drug combinations on Plasmodium lophurae in the chick. J. Infect. Dis. 86, 105.CrossRefGoogle ScholarPubMed
Robertson, G. I., Davey, D. G. & Fairley, N. H. (1952). Cross-resistance between ‘Daraprim’ and proguanil. Brit. Med. J. 2, 1255.CrossRefGoogle Scholar
Rollo, I. M. (1951). A 2:4-diamino pyrimidine in the treatment of proguanil-resistant laboratory malarial strains. Nature, Lond., 168, 332.CrossRefGoogle Scholar
Rollo, I. M. (1955). The mode of action of sulphonamides, proguanil and pyrimethamine on Plasmodium gallinaceum. Brit. J. Pharmacol. 10, 208.Google ScholarPubMed
Schmidt, L. H. & Genther, C. S. (1953). The antimalarial properties of 2,4-diamino-5-p– chlorophenyl-6-ethylpyrimidine (Daraprim). J. Pharmacol. 107, 61.Google ScholarPubMed
Singh, J., Nair, C. P. & Ray, A. P. (1954). Studies on Nuri strain of P. knowlesi. V. Acquired resistance to pyrimethamine. Indian J. Malariol. 8, 187.Google Scholar
Singh, J., Ray, A. P., Basu, P. C. & Nair, C. P. (1952). Acquired resistance to proguanil in Plasmodium knowlesi. Trans. R. Soc. Trop. Med. Hyg. 46, 639.CrossRefGoogle ScholarPubMed
Singh, J., Ray, A. P., Misra, B. G. & Nair, C. P. (1953). Synergistic action of quinine and pyrimethamine in P. falciparum infection. Indian J. Malariol. 7, 319.Google ScholarPubMed
Thurston, J. P. (1953). The chemotherapy of Plasmodium berghei. I. Resistance to drugs. Parasitology, 43 246.CrossRefGoogle ScholarPubMed