Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-24T17:21:15.691Z Has data issue: false hasContentIssue false
  • English
  • Français

ZETA POTENTIAL STUDY OF BARIUM HEXAGONAL FERRITES (BaFe12O19) FOR DRUG RELEASE

Published online by Cambridge University Press:  19 March 2012

S. Torres-Cadenas ,
R. Escudero-García ,
I. Espítia-Cabrera  and
M.E. Contreras-García
S. Torres-Cadenas
Affiliation:
Instituto de Investigaciones Metalúrgicas, Universidad Michoacana de San Nicolás de Hidalgo, C.U. Edificio “U”, C.P. 58030, Morelia, Michoacán, México.
R. Escudero-García*
Affiliation:
Instituto de Investigaciones Metalúrgicas, Universidad Michoacana de San Nicolás de Hidalgo, C.U. Edificio “U”, C.P. 58030, Morelia, Michoacán, México.
I. Espítia-Cabrera
Affiliation:
Facultad de Ingeniería Química, Universidad Michoacana de San Nicolás de Hidalgo, C.U. Edificio “E”, C.P. 58030, Morelia, Michoacán, México.
M.E. Contreras-García
Affiliation:
Instituto de Investigaciones Metalúrgicas, Universidad Michoacana de San Nicolás de Hidalgo, C.U. Edificio “U”, C.P. 58030, Morelia, Michoacán, México.
*
*Author to whom correspondence should be addressed: [email protected]
Get access

Abstract

Advances in nanotechnology observe new applications in many areas. Recently a great extent of research has been focused on the study of magnetic nanoparticles due to their potential application in areas such as bioscience and medicine. Magnetic nanoparticles are frequently used in biomedical and biotechnology applications since these particles associated to a given medicine are good candidates for drug release.

In this work zeta potential measurements of both hexagonal barium ferrites (magnetic nanoparticles), and an antibiotic known as tetracycline were carried out. The knowledge of the measured values establishes the possibility of bringing the two particles together in order to adsorb the tetracycline on the magnetic nanoparticles, since the surface charge play an essential role in the adsorption of the pharmaceutical drug on nanomaterials (i.e., tetracycline on barium ferrites).

Experimental results show the feasibility to adsorb tetracycline nanoparticles on barium hexaferrite solids at pH 7.0, based on the knowledge of the opposite electrical surface charge of the two solid species through the zeta potential measurement.

Keywords

Nanotechnologybiotechnologydrug releasebarium ferritestetracycline
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1376: Symposium S11 – Biomaterials for Medical Applications , 2012 , imrc11-1376-s11-p47
Copyright
Copyright © Materials Research Society 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

[1] Gupta, AK, Kumar, Ajay; Gupta, M. (2005). Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials. Vol. 26, No. 18, pp 3995–4021.Google Scholar
[2] Chen, Bao-An, Jin, Nan, Wang, Jun, Ding, Jiahua, Gao, Chong, Cheng, Jian, Xia, Guohua, Gao, Feng, Zhou, Yin, Chen, Yue, Zhou, Guina, Li, Xiaomao, Zhang, Yu, Tang, Men, Wang, Xuemei. (2010). The effect of magnetic nanoparticles of Fe3O4 on immune function in normal ICR mice. International Journal of Nanomedicine. Vol. 5, No. 1, pp 593–599.Google Scholar
[3] Arruebo, Manuel, Fernández-Pacheco, Rodrigo, Ricardo Ibarra, M., and Santamaría, Jesús. (2007). Magnetic nanoparticles for drug delivery applications. Nano Today. Vol. 2, pp 22–32.Google Scholar
[4] Wang, Jun, Chen, Yue, Chen, Baoan, Ding, Jiahua, Xia, Guohua, Gao, Chong, Cheng, Jian, Jin, Nan, Zhou, Ying, Li, Xiaomao, Tang, Meng, Wang, Xue Mei. (2010). Pharmacokinetic parameters and tissue distribution of magnetic Fe3O4 nanoparticles in mice. International Journal of Nanomedicine. Vol. 1, pp 861–866.Google Scholar
[5] Walton, TJ, Kolattukudy, PE., (1972). Determination of the structures of cutin monomers by a novel depolymerization procedure and combined gas chromatography and mass spectrometry. Biochemistry. Vol. 11, No. 10, pp 1885–1896.Google Scholar
[6 ] Vane, Leland M., and Zang, Gwen M., (2011). Effect of aqueous phase properties on clay particle zeta potential and electro-osmotic permeability: Implications for electro-kinetic soil remediation processes. Journal of Hazardous Materials. Vol. 55, No. 1-3, pp 1–22.Google Scholar