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Fabricating Neural and Cardiomyogenic Stem Cell Structures by a Novel Rapid Prototyping—the Inkjet Printing Method

Published online by Cambridge University Press:  01 February 2011

Tao Xu ,
Cassie Gregory ,
Peter Molnar  and
Thomas Boland
Tao Xu
Affiliation:
Department of Bioengineering, Clemson University Clemson, SC 29634-0905, U.S.A.
Cassie Gregory
Affiliation:
Department of Bioengineering, Clemson University Clemson, SC 29634-0905, U.S.A.
Peter Molnar
Affiliation:
Department of Bioengineering, Clemson University Clemson, SC 29634-0905, U.S.A.
Thomas Boland
Affiliation:
Department of Bioengineering, Clemson University Clemson, SC 29634-0905, U.S.A.
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Abstract

Direct printing of living cardiomyogenic stem cells and embryonic cortical neurons to generate complex cellular patterns and structures of such cells was demonstrated in the study. Furthermore, the immunostaining analyses and the whole-cell patch clamp recordings showed the cortical neurons grown in the printed cellular patterns and structures maintained their basic cellular functions, including neuronal phenotypes and electrophysiological properties. These results and findings may greatly prompt the inkjet printing method evolving into a viable and cost-effective approach for engineering human neural and cardiac tissues or even organs.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 845: Symposium AA – Nanoscale Materials Science in Biology and Medicine , 2004 , AA1.4
Copyright
Copyright © Materials Research Society 2005

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References

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