Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-28T17:00:52.041Z Has data issue: false hasContentIssue false
  • English
  • Français

Direct-Write Construction of Tissue-Engineered Scaffolds

Published online by Cambridge University Press:  17 March 2011

Anatoly M. Kachurin ,
Robert L. Stewart ,
Kenneth H. Church ,
William L. Warren ,
John P. Fisher ,
Antonios G. Mikos ,
Stine-Katherine Kraeft  and
Lan Bo Chen
Anatoly M. Kachurin
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
Robert L. Stewart
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
Kenneth H. Church
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
William L. Warren
Affiliation:
Sciperio, Inc., 5202-2 North Richmond Hill Road, Stillwater, OK 74075, U.S.A.
John P. Fisher
Affiliation:
Department of Bioengineering, Rice University, Houston, TX 77251, U.S.A.
Antonios G. Mikos
Affiliation:
Department of Bioengineering, Rice University, Houston, TX 77251, U.S.A.
Stine-Katherine Kraeft
Affiliation:
Dana–Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, U.S.A.
Lan Bo Chen
Affiliation:
Dana–Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, U.S.A.
Get access

Abstract

A computer-controlled xyz dispensing system called the Biological Architecture Tool (BAT) has been extensively tested in the creation of multilayered and three-dimensional biological objects: tissue scaffolds and plain and patterned cellular-array slides. The BAT dispensing system has proven its versatility and reliability in tissue engineering and biological experiments. The potential employments of modified versions of the xyz dispensers for in vivo minimally invasive surgery and other in vitro aspects of biological and medical research are discussed.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 698: Symposia Q/EE Electroative Polymers and Rapid Prototyping , 2001 , Q5.5.1
Copyright
Copyright © Materials Research Society 2002

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Stock, U. A. and Vacanty, J. P., Ann. Rev. Med. 52, 443 (2001).Google Scholar
2. Behravesh, E. and Mikos, A. G., presented at the MRS Spring Meeting, San Francisco, CA, 2001, in press.Google Scholar
3. Park, A., Wu, B., and Griffith, L. G., J. Biomater. Sci. Polym. Ed. 9, 8 (1998).Google Scholar
4. Behravesh, E., Yasko, A. W., Engel, P. S., and Mikos, A. G., Clin. Orth. Rel. Res. 367S, S118 (1999).Google Scholar
5. Yannas, I. V., Proc. Natl. Acad. Sci. USA 97, 9354 (2000).Google Scholar
6. Suggs, L. J. and Mikos, A. G., Cell Transplant. 8, 345 (1999).Google Scholar
7. Kraeft, S.-K., Sutherland, R., Gravelin, L., Hu, G. H., Farland, L. H., Richardson, P., Elias, A., and Chen, L. B., Clin. Cancer Res. 6, 434 (2000).Google Scholar