Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-28T08:48:38.926Z Has data issue: false hasContentIssue false
  • English
  • Français

Development of Au Nanowires for Recording Electrical Activity in Neural Cells

Published online by Cambridge University Press:  01 February 2011

Jesse Silverberg ,
Sucharita Saha ,
Donald O'Malley  and
Latika Menon
Jesse Silverberg
Affiliation:
Northeastern University, Physics, 110 Forsyth Street, Boston, MA, 02115, United States
Sucharita Saha
Affiliation:
[email protected], Northeastern University, Biology, Boston, MA, 02115, United States
Donald O'Malley
Affiliation:
[email protected], Northeastern University, Biology, Boston, MA, 02115, United States
Latika Menon
Affiliation:
[email protected], Northeastern University, Physics, 110 Forsyth Street, Boston, MA, 02115, United States
Get access

Abstract

The application of gold nanowire arrays for neuronal recording and stimulation is explored. The process of electrochemical anodization is utilized to grow an aluminum oxide template consisting of an array of closely packed cylindrical pores with diameters in the range of nanometers and micron scale depth. The method of electrodeposition is used to deposit gold within the pores forming a nanowire array. By means of micro and nanoscale fabrication processes, this array is integrated at one end with microscale gold electrodes. At the other end, neuron cells are cultured. Such nanowire-array structures will eventually be used to record and stimulate neuronal activity.

Keywords

nanoscalebiologicaldevices
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 951: Symposium E – Nanofunctional Materials, Nanostructures and Novel Devices for Biological and Chemical Detection , 2006 , 0951-E08-10
Copyright
Copyright © Materials Research Society 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Wang, K., Fishman, H.A., Dai, H., and Harris, J.S., Nano Lttrs. 6, 2043 (2006).Google Scholar
2. Patolsky, F., Timko, B.P., Yu, G., Fang, Y., Greytak, A.B., Zheng, G., Lieber, C.M., Science. 313, 1100 (2006).Google Scholar
3. O'Sullivan, J.P., Wood, G.C., Proc. Roy. Soc. of Lond. A. 317, 511 (1970).Google Scholar
4. Kimhy, Y., Spector, I., Barak, Y., Littauer, U.Z., Proc. Natl. Acad. Sci. 73, 462 (1976).Google Scholar
5. De Latt, S.L., Van Der Saag, P.T., In. Rev. Cyt. 74, 1 (1982).Google Scholar
6. Reagan, L.P., Ye, X., Mir, R., Depalo, R., Fluharty, J. Mol. Pharmacol. 38, 878 (1990).Google Scholar
7. Larcher, J.C., Basseville, M., Vaysierre, J.L., Cordeau-Lossouarn, L., Croizat, B., F. Gros Biochem. Biophys. Res. Commun. 185, 915 (1992).Google Scholar