Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-02T22:54:45.820Z Has data issue: false hasContentIssue false

Blood Compatibility of Metal Oxide Layers on Stainless-steel

Published online by Cambridge University Press:  11 February 2011

Kanji Tsuru
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Shinji Takemoto
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Tatsuhiro Yamamoto
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Satoshi Hayakawa
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Akiyoshi Osaka
Affiliation:
Biomaterials Laboratory, Faculty of Engineering, Okayama University, Okayama, 700–8530, JAPAN
Seisuke Takashima
Affiliation:
Co-Operative Research Center, Okayama University, Tsushima, Okayama, 701–1221, JAPAN
Get access

Abstract

We examined blood compatibility of titanium oxide layer on stainless-steel (SUS316L). The oxide layers with varied thickness were yielded on SUS316L plates by dip-coating of sol-gel solution starting from tetraethyltitanate. The blood compatibility was evaluated in term of platelet adhesion using platelet rich plasma. With increase in the thickness of the oxide layer, the number of adherent platelets decreased rapidly, reached minimum around 150nm. This indicated that the thickness of titanium oxide layer affected platelet adhesion.

Type
Articles
Copyright
Copyright © Materials Research Society 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1) Björk, I. and Lindahl, U., Mol. Cell. Biochem., 48, 161182 (1982).CrossRefGoogle Scholar
2) Christensen, K., Larsson, R., Emanuelsson, H., Elgue, G. and Larsson, A., Biomaterials, 22, 349355 (2001).CrossRefGoogle Scholar
3) Blezer, R., Fouache, B., Willems, G. M. and Lindhout, T., J. Biomed. Mater. Res., 37, 108113 (1997).3.0.CO;2-C>CrossRefGoogle Scholar
4) Klement, P., Du, Y. J., Berry, L., Andrew, M. and Chan, A. K. C., Biomaterials, 23, 527535 (2002).CrossRefGoogle ScholarPubMed
5) Takemoto, S., Tsuru, K., Hayakawa, S., Osaka, A., and Takashima, S., J. Sol-Gel Sci. Technol., 21, 97104 (2001).CrossRefGoogle Scholar
6) Takemoto, S., Tsuru, K., Hayakawa, S., Osaka, A., and Takashima, S., In: Bioceramics, Vol. 13, ed. by Giannini, S. and Moroni, A., Trans Tech Pub. Ltd. (2000), pp. 3538.Google Scholar
7) Nygren, H., Eriksson, C., and Lausmaa, J., J. Lab. Clin. Med., 129, 3546 (1997).CrossRefGoogle Scholar
8) Sunny, M. C., Sharma, C. P., J. Biomater. Appl., 6, 8998 (1991).CrossRefGoogle Scholar
9) Ikada, Y. et al., Polymer in medicine 2, Plenum, p. 101 (1981).Google Scholar