Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-02T23:16:41.129Z Has data issue: false hasContentIssue false

Study of Biosensors Based on Fe Nanowires

Published online by Cambridge University Press:  31 January 2011

Yang hao
Affiliation:
[email protected], Zhejiang University, Biomedical Engineering, Hangzhou, Zhejiang, China
Chen Yuquan
Affiliation:
[email protected], Zhejiang University, Biomedical Engineering, Hangzhou, Zhejiang, China
Get access

Abstract

Anodic aluminum oxide (AAO) template was prepared by using anodizing voltage step-decreasing method after two-step oxide method. Based on AAO template, Fe nanowires arrays were electrochemically deposited. Fe nanowires were coated by chitosan. Fe nanowires/chitosan was synthesized by glutaraldehyde as cross-linking reagent. By crosslinking α-human chorionic gonadotropin (α-HCG), biological probes with Fe nanowires/chitosan/antibody were prepared. An easy operating, easy taking and rapid reacting magnetic detecting system was developed after optimizing the geometry parameters of detect coil. Different concentration samples with 1, 2 and 5 g(Fe)/L were detected. The results show that the sensitivity of system is 0.2 g(Fe)/L and can be improve better.

Type
Research Article
Copyright
Copyright © Materials Research Society 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Cavalcanti, A. Shirinzadeh, B. and Kretly, L. C.. Nanomedicine: Nanotechnology, Biology and Medicine. 4, 127138 (2008).10.1016/j.nano.2008.03.001Google Scholar
2 Gomez-Hens, A., Fernandez-Romero, J. M. and Aguilar-Caballos, M. P.. TrAC Trends in Analytical Chemistry. 27, 394406 (2008).10.1016/j.trac.2008.03.006Google Scholar
3 Maki, W. C. Mishra, N. N. Cameron, E. G. Filanoski, B. Rastogi, S. K. and Maki, G. K.. Biosensors and Bioelectronics. 23, 780787 (2008).10.1016/j.bios.2007.08.017Google Scholar
4 Meyer, M. H. F. Krause, H.J. Hartmann, M. Miethe, P. J. Oster and M. Keusgen. Journal of Magnetism and Magnetic Materials. 311, 259263 (2007).10.1016/j.jmmm.2006.10.1175Google Scholar
5 Meyer, M. H. F. Stehr, M. Bhuju, S. Krause, H.J. Hartmann, M. Miethe, P. Singh, M. and Keusgen, M.. Journal of Microbiological Methods. 68, 218224 (2007).10.1016/j.mimet.2006.08.004Google Scholar
6 Ferretti, S. Paynter, S. Russell, D. A. Sapsford, K. E. and Richardson, D. J.. TrAC, Trends Anal. Chem. 19, 530540 (2000).10.1016/S0165-9936(00)00032-7Google Scholar