Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-24T14:07:16.322Z Has data issue: false hasContentIssue false
  • English
  • Français

Shape-Memory Properties of Radiopaque Micro-Composites from Amorphous Polyether Urethanes Designed for Medical Application

Published online by Cambridge University Press:  31 January 2011

Jing Cui ,
Karl Kratz  and
Andreas Lendlein
Jing Cui
Affiliation:
[email protected], Center for Biomaterial Development, Institute of Polymer Research, GKSS Research Center Geesthacht GmbH and Berlin-Brandenburg-Center for Regenerative Therapies (BCRT), PBI, Kantstrasse 55, 14513 Teltow, Germany, Teltow, 14513, Germany, +49 (0) 3328 352 328, +49 (0) 3328 352 452
Karl Kratz
Affiliation:
[email protected], Center for Biomaterial Development, Institute of Polymer Research, GKSS Research Center Geesthacht GmbH, PBI, Teltow, Germany
Andreas Lendlein
Affiliation:
[email protected], Institute of Polymer Research, GKSS Research Center, Teltow, Germany
Get access

Abstract

Biocompatible shape-memory polymers are of high significance for application in medical devices or instruments for minimally invasive surgery. To follow the medical device placement or changes in shape of the device in vivo by imaging methods like X-ray techniques, radiopacity of the polymer is required. In this work, we explored the shape-memory properties of radiopaque polymer composites prepared by incorporation of barium sulphate micro-particles in a biomedical grade polyether urethane (PEU) by co-extrusion technique. The filler content was varied from 5 wt% to 40 wt%, which was confirmed by thermal gravimetric analysis (TGA) measurements, while the particle distribution was visualized by scanning electron microscopy (SEM). The thermal and mechanical properties of the composites were investigated by means of dynamic mechanical analysis at varied temperature (DMTA) and tensile tests. The shape-memory properties of PEU composites were quantified in cyclic, thermomechanical experiments. A significant increase in Young’s modulus and a decrease in elongation at break were observed for PEU composites with increasing content of BaSO4, while the DMTA results were not affected by incorporation of the fillers. All samples exhibited excellent shape-memory properties with shape fixity rates (Rf) above 98% and values for shape recovery rate (Rr) in the range of 81% to 93%. The maximum stress (σmax) obtained under constant strain recovery conditions increased from 0.6 MPa to 1.4 MPa with raising amount of BaSO4, while the corresponding temperature (Tσ,max) as well as the switching temperature (Tsw) determined under stress-free conditions remained constant for all polymer composites.

Keywords

polymercompositememory
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1190: Symposium NN – Active Polymers , 2009 , 1190-NN03-22
Copyright
Copyright © Materials Research Society 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Lendlein, A., Langer, R., Science 2296, 1673 (2002).10.1126/science.1066102Google Scholar
2 Lendlein, A., Kelch, S., Clin. Hemorheol. Microcirc. 32, 105 (2005).Google Scholar
3 Metcalfe, A., Desfaits, A. C., Salazkin, I., Yahia, L., Sokolowski, W. M., Raymond, J., Biomaterials 24, 491 (2003).10.1016/S0142-9612(02)00362-9Google Scholar
4 Hu, J., Ding, X., Tao, X., Yu, J., J. Dong Hua Uni. (Engl. Ed.) 19, 3 (2002).Google Scholar
5 James, N. R., Philip, J., Jayakrishnan, A., Biomaterials 27, 160 (2006).10.1016/j.biomaterials.2005.05.099Google Scholar
6 Solís-Correa, R. E., Vargas-Coronado, R., Aguilar-Vega, M., Cauich-Rodríguez, J. V., Román, J. San, Marcos, A., J. Biomater. Sci. Polymer Edn 18, 561 (2007).10.1163/156856207780852488Google Scholar
7 Mohr, R., Kratz, K., Weigel, T., Luka-Gabor, M., Moneke, M., Lendlein, A., Proc. Nat. Acad. Sci. U.S.A. 103, 3540 (2006).10.1073/pnas.0600079103Google Scholar
8 Lin, J. R., Chen, L. W., J. Appl. Polym. Sci 69, 1575 (1998).10.1002/(SICI)1097-4628(19980822)69:8<1575::AID-APP12>3.0.CO;2-U3.0.CO;2-U>Google Scholar
9 Cho, J. W., Jung, Y. C., Chung, Y. C., Chun, B. C., J. Appl. Polym. Sci 93, 2410 (2004).10.1002/app.20747Google Scholar
10 Guo, X., J. Appl. Polym. Sci 109, 4015 (2008).10.1002/app.28505Google Scholar
11 Lendlein, A., Kelch, S., Angew. Chem. Int. Ed. 41, 2034 (2002).10.1002/1521-3773(20020617)41:12<2034::AID-ANIE2034>3.0.CO;2-M3.0.CO;2-M>Google Scholar