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Self-Assembled Lipid Tubules: Synthesis, Characterization, and Ordered Arrays

Published online by Cambridge University Press:  01 February 2011

Yue Zhao
Affiliation:
[email protected] of Central FloridaAdvanced Materials Processing and Analysis Center, Dept. of Mechanical, Materials, and AerospaceOrlando FL 32816United States
Nidhi Mahajan
Affiliation:
[email protected], Unviersity of Central Florida, Advanced Materials Processing and Analysis Center, Dept. of Mechanical, Materials, and Aerospace, Orlando, FL, 32816, United States
Jiyu Fang
Affiliation:
[email protected], Unviersity of Central Florida, Advanced Materials Processing and Analysis Center, Dept. of Mechanical, Materials, and Aerospace, Orlando, FL, 32816, United States
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Abstract

The rolling of lipid bilayer sheets into hollow cylindrical tubules have emerged as a group of interesting supramolecular nanostructures. Here, we image the self-assembled tubules of 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphochloline (DC8,9PC) with atomic force microscopy. Nanoscale ripple structures with a periodicity of ~ 200nm in the cylindrical lipid tubules are observed. We develop two simple methods based on microfluidic networks and surface patterning to produce two dimensional ordered arrays of parallel aligned lipid tubules on substrates.

Type
Research Article
Copyright
Copyright © Materials Research Society 2006

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