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Preparation of porous structures with shape memory properties from biodegradable polymeric networks

Published online by Cambridge University Press:  27 February 2012

Shahriar Sharifi
Affiliation:
Department of Biomedical Engineering, University Medical Centre Groningen, PO Box 196, 9700AD, Groningen, The Netherlands.
Sebastien Blanquer
Affiliation:
Department of Biomaterials Science and Technology, University of Twente, PO Box 217, 7500 AE, Enschede, The Netherlands.
Dirk W. Grijpma
Affiliation:
Department of Biomedical Engineering, University Medical Centre Groningen, PO Box 196, 9700AD, Groningen, The Netherlands. Department of Biomaterials Science and Technology, University of Twente, PO Box 217, 7500 AE, Enschede, The Netherlands.
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Abstract

Preparing porous biodegradable structures from shape memory polymers can combine the structure-defining properties of porous structures with the minimally invasive implanting possibilities of shape memory polymers. In this study, porous biodegradable shape memory structures were prepared using photo-crosslinked networks based on poly(D,L-lactide-co-trimethylene carbonate). The characteristic shape memory properties of the structures, such as their shape fixity at a low temperature of 0 oC and their full shape recovery upon heating to physiological temperatures, were excellent. This makes these biodegradable and biocompatible structures very well-suited for use as self-deploying implants in medical applications like tissue engineering, drug delivery and the support of soft tissues.

Type
Research Article
Copyright
Copyright © Materials Research Society 2012

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