Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-15T11:14:10.562Z Has data issue: false hasContentIssue false

Organoapatites: New Materials for Regenerative Artificial Bone

Published online by Cambridge University Press:  15 February 2011

Samuel I. Stupp
Affiliation:
Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign
Jacqueline A. Hanson
Affiliation:
Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign
Glenn W. Ciegler
Affiliation:
Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign
G. C. Mejicano
Affiliation:
Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign
Jo Ann Eurell
Affiliation:
Department of Veterinary Biosciences, University of Illinois at Urbana-Champaign
Ann L. Johnson
Affiliation:
Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign
Get access

Extract

The objective of this work is to identify synthetic pathways for materials useful in the effective repair of the skeletal system. Ideally a universal artificial bone would be identified that can function as a cementitious, pseudoplastic, or structural material. The cementitious form would be very important for bone adhesives that repair bone fractures and restore bone defects. The pseudoplastic form would aid in the in situ reconstruction of anatomical defects and the structural material could be used to prefabricate prostheses. It is critical of course for all these forms of the artificial bone to have strongly regenerative properties so that as implants they would integrate microscopically with natural bone.

Type
Research Article
Copyright
Copyright © Materials Research Society 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Ciegler, G.W. and Stupp, S. I, Trans. 11th Annual Meeting Soc. for Biomaterials, Vol VIII, 165 (1985).Google Scholar
2. Stupp, S.l., Ciegler, G.W., Mejicano, G.C. and Dudas, C.M., Trans. 12th Annual Meeting Soc. for Biomaterials, Vol. IX, 164 (1986).Google Scholar
3. Mejicano, G.C. and Stupp, S.I., Trans. 12th Annual Meeting Soc. for Biomaterials, Vol. IX, 33 (1986).Google Scholar
4. Stupp, S.I., Johnson, A.L., Ciegler, G.W., Mejicano, G.C. and Hanson, J.A., Trans. 13th Annual Meeting Soc. for Biomaterials, Vol. X, 247 (1987).Google Scholar
5. Stupp, S.I., Eurell, J.A., Hanson, J.A. and Ciegler, G.W., Trans. 15th Annual Meeting Soc. for Biomaterials, Vol. XII, 108 (1989).Google Scholar
6. Stupp, S.I. and Ciegler, G.W., J. Biomedical Materials Research, Vol.26(2), 169 (1992).Google Scholar
7. Stupp, S.I., Mejicano, G.C. and Hanson, J.A.: Organoapatites: New Materials for Artificial Bone. Il. Hardening Reactions and Properties, submitted for publication.Google Scholar
8. Stupp, S.I., Hanson, J.A., Eurell, J.A., Ciegler, G.W., and Johnson, A.L.: Organoapatites: New Materials for Artificial Bone. Ill. Biological Testing, submitted for publication.Google Scholar