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Neural Cell Attachment on Metal Ion Implanted Glass Surfaces

Published online by Cambridge University Press:  07 October 2011

Emel Sokullu-Urkac ,
Ahmet Oztarhan ,
Ismet Deliloglu-Gurhan ,
Sultan Gulce-Iz ,
Feyzan Ozdal-Kurt  and
Ian G. Brown
Emel Sokullu-Urkac*
Affiliation:
Surface Modification Laboratory, Ege University, 35100 Izmir, Turkey
Ahmet Oztarhan
Affiliation:
Surface Modification Laboratory, Ege University, 35100 Izmir, Turkey Bioengineering Department, Ege University, 35100 Izmir, Turkey
Ismet Deliloglu-Gurhan
Affiliation:
Bioengineering Department, Ege University, 35100 Izmir, Turkey
Sultan Gulce-Iz
Affiliation:
Bioengineering Department, Ege University, 35100 Izmir, Turkey
Feyzan Ozdal-Kurt
Affiliation:
Biology Department, Celal Bayar University, 45040 Manisa, Turkey
Ian G. Brown
Affiliation:
Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
*
*Email: [email protected]
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Abstract

We have explored the application of ion implantation as a tool for the enhancement of neural cell growth on glass surfaces. Glass substrates were ion implanted with gold and with carbon using a metal vapor vacuum arc (MEVVA) ion source-based implantation system at Ege University Surface Modification Laboratory. The implantation dose was varied over the range 1014 – 1017 ions/cm2 and the ion energy spanned the range 20 – 80 keV. B35 neural cells were seeded and incubated on the implanted substrates for 48h at 37°C. After 2-days in culture the cell attachment behavior was characterized using phase contrast microscopy. The adhesion and direct contact of neural cells on these ion implanted glass surfaces were observed

Keywords

ion-implantationbiomedicalsurface reaction
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1354: Symposium II – Ion Beams—New Applications from Mesoscale to Nanoscale , 2011 , mrss11-1354-ii01-04
Copyright
Copyright © Materials Research Society 2011

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References

REFERENCES

1. Brown, I.G., Bjornstad, K.A., Blakely, E.A., Galvin, J.E., Monteiro, O.R. and Sangyuenyongpipat, S., Plasma Phys. Control. Fusion 45, 547–554 (2003).10.1088/0741-3335/45/5/303Google Scholar
2. Bayliss, S.C., Buckberry, L.D., Fletcher, I. and Tobin, M.J., Sensor Actuat. A-Phys. 74/1-3, 139-142 (1999).10.1016/S0924-4247(98)00346-XGoogle Scholar
3. Schwab, M.E., Kapfhammer, J.P. and Bandtlow, C.E., Annu. Rev. Neurosci. 16, 565–595, (1993).10.1146/annurev.ne.16.030193.003025Google Scholar
4. Otey, C.A., Boukhelifa, M. and Maness, P., Method. Cell Biol. 71, 287–304, (2003).10.1016/S0091-679X(03)01013-6Google Scholar
5. Oztarhan, A., Brown, I., Bakkaloglu, C., Watt, G., Evans, P., Oks, E., Nikolaev, A. and Tek, Z., Surf. Coat. Technol., 196, 327 (2005).10.1016/j.surfcoat.2004.08.178Google Scholar
6. Brown, I.G. and Godechot, X., IEEE Trans. Plasma Sci. 19, 713 (1991).10.1109/27.108403Google Scholar
7. Gushenets, I., Nikolaev, A.G., Oks, E.M., Vintizenko, L.G., Yushkov, G.Yu., Oztarhan, A. and Brown, I.G., Rev. Sci. Instrum. 77, 063301 (2006).10.1063/1.2206778Google Scholar
8. Fan, Y.W., Cui, F.Z., Chen, L.N., Zhai, Y. and Xu, Q.Y., Surf. Coat. Technol. 131/1-3, 355-359 (2000).10.1016/S0257-8972(00)00812-4Google Scholar
9. Rauvala, H., J. Cell Biol. 98:3, 1010-1016 (1984).10.1083/jcb.98.3.1010Google Scholar