Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-24T11:38:48.174Z Has data issue: false hasContentIssue false
  • English
  • Français

Mg-Ti: A Possible Biodegradable, Biocompatible, Mechanically Matched Material for Temporary Implants

Published online by Cambridge University Press:  21 March 2011

Ilona Hoffmann ,
Yang-Tse Cheng ,
David A. Puleo ,
Guangling Song  and
Richard A. Waldo
Ilona Hoffmann*
Affiliation:
Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506, U.S.A.
Yang-Tse Cheng
Affiliation:
Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506, U.S.A.
David A. Puleo
Affiliation:
Center for Biomedical Engineering, University of Kentucky, Lexington, KY40506, U.S.A.
Guangling Song
Affiliation:
Chemical Sciences and Materials Systems Laboratory, General Motors Global Research and Development Center, Warren, MI 48098, U.S.A.
Richard A. Waldo
Affiliation:
Chemical Sciences and Materials Systems Laboratory, General Motors Global Research and Development Center, Warren, MI 48098, U.S.A.
*
*[email protected]
Get access

Abstract

In recent years there has been a renewed interest in magnesium alloys for applications as temporary biomedical implants because magnesium is both biocompatible and biodegradable. However, the rapid corrosion rate of magnesium in physiological environments has prevented its successful use for temporary implants. Since alloying is one of the routes to slow down corrosion, we report in this publication our investigation of Mg-Ti alloys fabricated by high-energy ball milling as possible materials for biocompatible and biodegradable implants. Titanium was chosen mainly because of its proven biocompatibility and corrosion resistance. Corrosion tests carried out by immersing the Mg-Ti alloys in Hank’s Solution at 37°C showed significantly improved corrosion resistance of the alloy in comparison to pure magnesium. Thus, Mg-Ti alloys are promising new biodegradable and biocompatible materials for temporary implants.

Keywords

biomedicalMgcorrosion
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1301: Symposium V/NN/OO/PP – Soft Matter, Biological Materials and Biomedical Materials—Synthesis, Characterization and Applications , 2011 , mrsf10-1301-oo06-07
Copyright
Copyright © Materials Research Society 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Park, J. and Lakes, R.S., Biomaterials – An Introduction, (Springer, 2007).Google Scholar
2. Song, G.-L., Corrosion Science 49, 1696–1701 (2007).Google Scholar
3. Zberg, B., Uggowitzer, P. J., and Loffler, J. F., Nature Materials 8, 887–891 (2009).Google Scholar
4. Elin, R. J., American Journal of Clinical Pathology 102, 616–622 (1994).Google Scholar
5. Shils, Maurice E., Olson, James A., and Shike, Moshe (Ed.), Modern Nutrition in Health and Disease, (Lea & Febiger, 1994).Google Scholar
6. Zreiqat, H., Howlett, C. R., Zannettino, A., Evans, P., Schulze-Tanzil, G., Knabe, C., and Shakibaei, M., Journal of Biomedical Materials Research 62, 175–184 (2002).Google Scholar
7. Narayan, R. (ed), Biomedical Materials, (Springer, 2009).Google Scholar
8. Handbook of Chemistry and Physics, (2010–2011).Google Scholar
9. Cheng, Y.-T., Verbrugge, M. W., Balogh, M. P., Rodak, D. E., Lukitsch, M., US patent 7,651,732 (January 26, 2010).Google Scholar
10. Landolt-Bornstein, New Series IV/5.Google Scholar
11. Koch, C. (ed), Nanostructured Materials: Processing, Properties, and Applications (William Andrew, 2007).Google Scholar
12. Asano, K., Enoki, H., and Akiba, E., Journal of Alloys and Compounds 480, 558–563 (2009).Google Scholar
13. Kalisvaart, W. P. and Notten, P. H. L., Journal of Materials Research 23, 2179–2187 (2008).Google Scholar
14. Liang, G. and Schulz, R., Journal of Materials Science 38, 1179–1184 (2003).Google Scholar
15. Maweja, K., Phasha, M., and van der Berg, N., Powder Technology 199, 256–263 (2010).Google Scholar
16. Wilkes, D. M. J., Goodwin, P. S., WardClose, C. M., Bagnall, K., and Steeds, J., Materials Letters 27, 47–52 (1996).Google Scholar
17. Benjamin, J. S., Metallurgical Transactions 1, 2943–2951 (1970).Google Scholar
18. Zidoune, M., Grosjean, M. H., Roue, L., Huot, J., and Schulz, R., Corrosion Science 46, 3041–3055 (2004).Google Scholar
19. Song, G.-L., Atrens, A., StJohn, D., Magnesium Technology, Hryn, John N. (ed.), 255-262 (2001).Google Scholar
20. Xu, Z., Song, G-L., and Haddad, D., Magnesium Technology, (2011) (accepted for publication).Google Scholar