Hostname: page-component-586b7cd67f-t8hqh Total loading time: 0 Render date: 2024-11-28T15:17:40.234Z Has data issue: false hasContentIssue false
  • English
  • Français

Matrix Assisted Pulsed Laser Evaporation of Poly (D, L) Lactic Acid Films

Published online by Cambridge University Press:  01 February 2011

Timothy M. Patz ,
Anand Doraiswamy ,
Roger Narayan ,
Nicola Menegazzo ,
Christine Kranz ,
Boris Mizaikoff ,
Rohit Modi  and
Douglas B. Chrisey
Timothy M. Patz
Affiliation:
Bioengineering Program and School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA, USA
Anand Doraiswamy
Affiliation:
Bioengineering Program and School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA, USA
Roger Narayan
Affiliation:
Bioengineering Program and School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA, USA
Nicola Menegazzo
Affiliation:
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA
Christine Kranz
Affiliation:
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA
Boris Mizaikoff
Affiliation:
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA
Rohit Modi
Affiliation:
US Naval Research Laboratory, Washington, DC, USA
Douglas B. Chrisey
Affiliation:
US Naval Research Laboratory, Washington, DC, USA
Get access

Abstract

We have deposited poly (D, L lactic acid) (PDLLA) thin films using matrix assisted pulsed laser evaporation (MAPLE). FTIR spectroscopy revealed that the PDLLA had similar absorption bands to the dropcast material. X-ray photoelectron spectroscopy has shown that peaks corresponding to C-H, C-O and C=O represented 38.4, 30.1 and 31.4% of the C1s spectrum, respectively. XPS O1s analysis revealed that the O=C and O-C components make up 52 and 48 % of the O1s content. Atomic force microscopy revealed that MAPLE deposition provides smooth, continuous thin biomaterial films. These matrix assisted pulsed laser evaporation-deposited biomaterial thin films may serve to improve the implant/tissue interface.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 845: Symposium AA – Nanoscale Materials Science in Biology and Medicine , 2004 , AA5.8
Copyright
Copyright © Materials Research Society 2005

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Babensee, J. E., Anderson, J. M., McIntire, L. V., and Mikos, A. G., Adv. Drug Delivery Rev. 33, 111 (1998).Google Scholar
2. Shichiri, M., Sakakida, M., Nishida, K., and Shimoda, S., Artif. Organs 22, 32 (1998).Google Scholar
3. Reuben, B. G., Perl, O., Morgan, N.L., Stratford, P., Dudley, L. Y., and Hawes, C., J. Chem. Tech. Biotech. 63, 85 (1995).Google Scholar
4. Slavkin, H. C., J. Amer. Dental Assoc. 127, 1254 (1996).Google Scholar
5. Ellenbogen, K. A., Wood, M. A., Gilligan, D. M., Zmijewski, M., and Mans, D., Pacing Clin. Electrophysiology 22, 39 (1999).Google Scholar
6. Chrisey, D. B., Pique, A., McGill, R. A., Horwitz, J. S., Ringeisen, B. R., Bubb, D. M., and Wu, P. K., Chem. Rev. 103, 553 (2003)Google Scholar
7. Kister, G., Cassanas, G., and Vert, M., Polymer 39, 267 (1998).Google Scholar
8. Leuchtner, R. E., Chrisey, D. B., Horwitz, J. S., and Grabowski, K. S., Surf. Coat. Technol. 51, 476 (1992).Google Scholar
9. Beamson, G. and Briggs, D., High Resolution XPS of Organic Polymers, (Wiley, New York, 1992).Google Scholar
10. Inagaki, N., Narushima, K., and Lim, S. K., J. Appl. Polym. Sci. 89, 96 (2003).Google Scholar
11. Mayumi, A., Kanie, O., Kitaoka, T., Wariishi, H., and Tanaka, H., J. Fac. Agr., Kyushu Univ. 48, 97 (2003).Google Scholar