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High Performance Micromachined Planar Field-Asymmetric Ion Mobility Spectrometers for Chemical and Biological Compound Detection

Published online by Cambridge University Press:  01 February 2011

Raanan A. Miller ,
Angela Zapata ,
Erkinjon G. Nazarov ,
Evgeny Krylov  and
Gary A. Eiceman
Raanan A. Miller
Affiliation:
Sionex Corporation, Wellesley Hills, MA
Angela Zapata
Affiliation:
Charles Stark Draper Laboratory, Cambridge, MA
Erkinjon G. Nazarov
Affiliation:
New Mexico State University, Chemistry and Biochemistry Department, Las Cruces, NM
Evgeny Krylov
Affiliation:
New Mexico State University, Chemistry and Biochemistry Department, Las Cruces, NM
Gary A. Eiceman
Affiliation:
New Mexico State University, Chemistry and Biochemistry Department, Las Cruces, NM
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Abstract

The micromachined Planar High Field Asymmetric Waveform Ion Mobility Spectrometer (PFAIMS) is a novel detector for chemical and biological sensing applications. This detector fills an unmet market need, providing spectrometer capabilities and extremely high sensitivity, at a cost comparable to stand-alone sensors. The PFAIMS is quantitative, and has detection limits down to the parts-per-trillion. The performance of the PFAIMS in a number of applications ranging from industrial to biomedical, where it is used as both a stand alone sensor, and as a gas chromatographic detector are demonstrated. These applications include the detection of xylene isomers and non-invasive medical diagnosis through breath analysis.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 729: Symposium U – MEMS and BioMEMS , 2002 , U4.1
Copyright
Copyright © Materials Research Society 2002

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References

1. Buryakov, I.A., Krylov, E.V., Nazarov, E.G., and Rasulev, U.Kh., Int. J. Mass Spectrometry and Ion Processes 1993, 48(1), 114.Google Scholar
2. Carnahan, B., Day, S., Kouznetsov, V., Matyjaszczyk, M., Tarassov, A., “Field Ion Spectrometery – A New Analytical Technology For Trace Gas Analysis”, Proceedings of the 1996 International Conference on Advances in Instrumentation and Control, ISA '96,Google Scholar
3. Miller, R. A., Eiceman, G. A., Nazarov, E. G., and King, A. T., “A Novel Micromachined HighField Asymmetric Waveform Ion Mobility Spectrometer”, Sensors and Actuators B 67 (2000) 300–306.Google Scholar
4. Miller, R. A., Eiceman, G. A., Nazarov, E. G., and King, A. T., “A MEMS Radio-Frequency Ion Mobility Spectrometer for Chemical Agent Detection”, Proceedings of the 2000 Solid-State Sensors and Actuators Workshop, Hilton Head, SC, June 2000 Google Scholar
5. Eiceman, G. A., Karpas, Z., Ion Mobility Spectrometry, CRC Press, 1994.Google Scholar
6.SRI consulting website (http://www.sriconsulting.com)Google Scholar
7. Miller, R. A., Nazarov, E. G., Eiceman, G. A., King, A. Thomas, “A MEMS Radio-Frequency ion mobility spectrometer for chemical vapor detection,” Sensors and Actuators A 91 (2001) 307–318.Google Scholar
8. Eiceman, G. A., Tadjikov, B., Krylov, E., Nazarov, E. G., Miller, R. A., Westbrook, J., Funk, P., “Miniature radio-frequency mobility analyzer as a gas chromatographic detector for oxygen-containing volatile organic compounds, pheromones and other insect attractants”, J. Chromatography A, 2001, v917, 205–17.Google Scholar
9. McNair, H. M., Miller, J. M., Basic Gas Chromatography, John Wiley & Sons, 1997.Google Scholar
10. Miller, R. A., Eiceman, G. A., Nazarov, E. G., Zapata, A., Krylov, E., Tadjikov, B., “A Micromachined Radio Frequency Ion Mobility Spectrometer as a Gas Chromatograph Detector,” International Journal for Ion Mobility Spectrometry, 4(2001)2, pp. 58–61.Google Scholar
11. Karpas, Z., Lorber, A., Israeli Patent Application #141233, 2001.Google Scholar
12. Phillips, M., Scientific American, July 1992, pp. 74–79.Google Scholar
13. Eiceman, G. A., Nazarov, E. G., Miller, R. A., Krylov, E., Zapta, A., “Micro-machined planar field asymmetric ion mobility spectrometer as a gas chromatographic detector,” accepted for publication Analyst, 2002, 127.Google Scholar