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Characterization of a Polyanhydride Series by Ftir

Published online by Cambridge University Press:  15 February 2011

Mark R. Kreitz ,
Kathleen J. Pekarek  and
Edith Mathiowitz
Mark R. Kreitz
Affiliation:
Artificial Organs Laboratory, Brown University, Providence, Rhode Island 02912
Kathleen J. Pekarek
Affiliation:
Artificial Organs Laboratory, Brown University, Providence, Rhode Island 02912
Edith Mathiowitz
Affiliation:
Artificial Organs Laboratory, Brown University, Providence, Rhode Island 02912
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Abstract

Using Fourier-transform infrared (FTIR) spectroscopy we have characterized a polyanhydride copolymer series composed of various ratios of the diacids 1,3-bis(p -carboxyphenoxy)propane (CPP) and sebacic acid (SA). Typical peaks corresponding to the aliphatic-aliphatic (SA-SA), aromatic-aliphatic (CPP-SA), and aromatic-aromatic (CPP-CPP) diads were found in the 1820- 1710 cm−1 wavenumber range. Further peaks corresponding to the SA-SA diads were identified in the fingerprint region at 1382, 1360, 1307, and 1286 cm−1. These peak characterizations facilitate identification of bond distribution in the CPP-SA copolymer as well as other polyanhydride copolymers, and correlate well with previously presented information obtained with nuclear magnetic resonance (NMR) spectroscopy and X-ray powder diffraction.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 331: Symposium T – Biomaterials for Drug and Cell Delivery , 1993 , 235
Copyright
Copyright © Materials Research Society 1994

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