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Application of clay as a means of support to biomaterial with anti-inflammatory agents

Published online by Cambridge University Press:  01 February 2011

M.L. Domínguez-Patiño ,
M Chávez-Castillo ,
A. Rodríguez-Martínez ,
R.M. Melgoza Alemán ,
E Jiménez-Ferrer  and
M. Herrera-Ruíz
M.L. Domínguez-Patiño
Affiliation:
Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, CP 62209,Cuernavaca, Morelos, México. E-mail: [email protected]
M Chávez-Castillo
Affiliation:
Posgrado en Ingeniería y Ciencias Aplicadas, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, CP 62209,Cuernavaca, Morelos, México. E-mail: [email protected]
A. Rodríguez-Martínez
Affiliation:
Centro de Investigación en Ingeniería y Ciencias Aplicadas, Universidad Autónoma del Estado de Morelos, México
R.M. Melgoza Alemán
Affiliation:
Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, CP 62209,Cuernavaca, Morelos, México. E-mail: [email protected]
E Jiménez-Ferrer
Affiliation:
Centro de Investigación Biomédica del Sur (IMSS), Argentina No. 1, Col. Centro Xochitepec, Morelos 62790, México
M. Herrera-Ruíz
Affiliation:
Centro de Investigación Biomédica del Sur (IMSS), Argentina No. 1, Col. Centro Xochitepec, Morelos 62790, México
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Abstract

In the last fifteen years, there have been significant changes in the production of medicines, mainly in the addition of new components to the formulation of solid dosage forms. The current trend of “back to nature” to lead to a healthier life has led those who are engaged in the pharmaceutical field to develop new formulations that allow the use of natural products of plant origin

For example, excipient ingredients, used as carriers for a drug's active ingredients, are now being used. These are incorporated into a drug in order to facilitate the drug's preparation, maintenance, or administration. The excipient is beneficial to the patient because it allows the drug to be easily administered and absorbed by the human body [3]

There is evidence that the clays have great potential for both absorption and adsorption due to its tiny particles. In addition, it has been reported that some clays have an effective antiseptic and healing ability [5–8]

In the present work, a clay called bentonite was tested as a support vehicle of an inflammatory agent derived from a Mexican native plant called Distictis buccinatoria, commonly named “Tonacaxóchitl”. Studies carried out by Rojas et al. have shown that the organic extract of this plant has important antibacterial, antifungal, cytotoxic and anti-inflammatory properties [9]

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1277: Biomaterials–2010 , 2010 , S6-15
Copyright
Copyright © Materials Research Society 2010

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