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The Polyvalent Gold Nanoparticle Conjugate—Materials Synthesis, Biodiagnostics, and Intracellular Gene Regulation

Published online by Cambridge University Press:  31 January 2011

Chad A. Mirkin
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Abstract

Advances in nanoscale directed assembly strategies have enabled researchers to analogize atomic assembly via chemical reactions and nanoparticle assembly, creating a new nanoscale “periodic table.” We are just beginning to realize the nanoparticle equivalents of molecules and extended materials and are currently developing the ground rules for creating programmable nanometer-scale coordination environments. The ability to create a diverse set of nanoscale architectures from one class of nanoparticle building blocks would allow for the synthesis of designer materials, wherein the physical properties of a material could be predicted and controlled a priori. Our group has taken the first steps toward this goal and developed a means of creating tailorable assembly environments using DNA-nanoparticle conjugates. These nanobioconjugates combine the discrete plasmon resonances of gold nanoparticles with the synthetically controllable and highly selective recognition properties of DNA. Herein, we elucidate the beneficial properties of these materials in diagnostic, therapeutic, and detection capabilities and project their potential use as nanoscale assembly agents to realize complex three-dimensional nanostructures.

Type
Research Article
Information
MRS Bulletin , Volume 35 , Issue 7: Advances in Scattering Probes for Materials , July 2010 , pp. 532 - 539
Copyright
Copyright © Materials Research Society 2010

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References

1.Rosi, N.L., Mirkin, C.A., Chem. Rev. 105, 1547 (2005).CrossRefGoogle Scholar
2.Bell, A.T., Science 299, 1688 (2003).CrossRefGoogle Scholar
3.Daniel, M.-C., Astruc, D., Chem. Rev. 104, 293 (2003).CrossRefGoogle Scholar
4.Ozbay, E., Science 311, 189 (2006).CrossRefGoogle Scholar
5.Talapin, D.V., Lee, J.-S., Kovalenko, M.V., Shevchenko, E.V., Chem. Rev. 110, 389 (2009).CrossRefGoogle Scholar
6.Baughman, R.H., Zakhidov, A.A., de Heer, W.A., Science 297, 787 (2002).CrossRefGoogle Scholar
7.Murray, C.B., Kagan, C.R., Bawendi, M.G., Annu. Rev. Mater. Sci. 30, 545 (2000).CrossRefGoogle Scholar
8.Tao, A.R., Habas, S., Yang, P.D., Small 4, 310 (2008).CrossRefGoogle Scholar
9.Jin, R., Charles Cao, Y., Hao, E., Metraux, G.S., Schatz, G.C., Mirkin, C.A., Nature 425, 487 (2003).CrossRefGoogle Scholar
10.Grzelczak, M., Perez-Juste, J., Mulvaney, P., Liz-Marzan, L.M., Chem. Soc. Rev. 37, 1783 (2008).CrossRefGoogle Scholar
11.Qin, L.D., Park, S., Huang, L., Mirkin, C.A., Science 309, 113 (2005).CrossRefGoogle Scholar
12.Kalsin, A.M., Fialkowski, M., Paszewski, M., Smoukov, S.K., Bishop, K.J.M., Grzybowski, B.A., Science 312, 420 (2006).CrossRefGoogle Scholar
13.Mirkin, C.A., Letsinger, R.L., Mucic, R.C., Storhoff, J.J., Nature 382, 607 (1996).CrossRefGoogle Scholar
14.Nykypanchuk, D., Maye, M.M., van der Lelie, D., Gang, O., Nature 451, 549 (2008).CrossRefGoogle Scholar
15.Park, S.Y., Lytton-Jean, A.K.R., Lee, B., Weigand, S., Schatz, G.C., Mirkin, C.A., Nature 451, 553 (2008).CrossRefGoogle Scholar
16.Shevchenko, E.V., Talapin, D.V., Kotov, N.A., O'Brien, S., Murray, C.B., Nature 439, 55 (2006).CrossRefGoogle Scholar
17.Redl, F.X., Cho, K.S., Murray, C.B., O'Brien, S., Nature 423, 968 (2003).CrossRefGoogle Scholar
18.Leunissen, M.E., Christova, C.G., Hynninen, A.-P., Royall, C.P., Campbell, A.I., Imhof, A., Dijkstra, M., van Roij, R., van Blaaderen, A., Nature 437, 235 (2005).CrossRefGoogle Scholar
19.Férey, G., Chem. Soc. Rev. 37, 191 (2008).CrossRefGoogle Scholar
20.Storhoff, J.J., Lazarides, A.A., Mucic, R.C., Mirkin, C.A., Letsinger, R.L., Schatz, G.C., J. Am. Chem. Soc. 122, 4640 (2000).CrossRefGoogle Scholar
21.Jin, R.C., Wu, G.S., Li, Z., Mirkin, C.A., Schatz, G.C., J. Am. Chem. Soc. 125, 1643 (2003).CrossRefGoogle Scholar
22.Lytton-Jean, A.K.R., Mirkin, C.A., J. Am. Chem. Soc. 127, 12754 (2005).CrossRefGoogle Scholar
23.Taton, T.A., Mirkin, C.A., Letsinger, R.L., Science 289, 1757 (2000).CrossRefGoogle Scholar
24.Taton, T.A., Lu, G., Mirkin, C.A., J. Am. Chem. Soc. 123, 5164 (2001).CrossRefGoogle Scholar
25.Jin, R., Cao, Y., Mirkin, C.A., Kelly, K.L., Schatz, G.C., Zheng, J.G., Science 294, 1901 (2001).CrossRefGoogle Scholar
26.Elghanian, R., Storhoff, J.J., Mucic, R.C., Letsinger, R.L., Mirkin, C.A., Science 277, 1078 (1997).CrossRefGoogle Scholar
27.Park, S.J., Taton, T.A., Mirkin, C.A., Science 295, 1503 (2002).CrossRefGoogle Scholar
28.Mitchell, G.P., Mirkin, C.A., Letsinger, R.L., J. Am. Chem. Soc. 121, 8122 (1999).CrossRefGoogle Scholar
29.Lee, J.-S., Lytton-Jean, A.K.R., Hurst, S.J., Mirkin, C.A., Nano Lett. 7, 2112 (2007).CrossRefGoogle Scholar
30.Lu, Y.R., Bangsaruntip, S., Wang, X.R., Zhang, L., Nishi, Y., Dai, H.J., J. Am. Chem. Soc. 128, 3518 (2006).CrossRefGoogle Scholar
31.Zheng, G., Qin, L., Mirkin, C.A., Angew. Chem. Int. Ed. 47, 1938 (2008).CrossRefGoogle Scholar
32.Alivisatos, A.P., Johnsson, K.P., Peng, X.G., Wilson, T.E., Loweth, C.J., Bruchez, M.P., Schultz, P.G., Nature 382, 609 (1996).CrossRefGoogle Scholar
33.Patel, P.C., Giljohann, D.A., Seferos, D.S., Mirkin, C.A., Proc. Nat. Acad. Sci. U.S.A. 105, 17222 (2008).CrossRefGoogle Scholar
34.Seferos, D.S., Giljohann, D.A., Hill, H.D., Prigodich, A.E., Mirkin, C.A., J. Am. Chem. Soc. 129, 15477 (2007).CrossRefGoogle Scholar
35.Seferos, D.S., Giljohann, D.A., Rosi, N.L., Mirkin, C.A., Chembiochem 8, 1230 (2007).CrossRefGoogle Scholar
36.Macfarlane, R.J., Lee, B., Hill, H.D., Senesi, A.J., Seifert, S., Mirkin, C.A., Proc. Nat. Acad. Sci. 106, 10493 (2009).CrossRefGoogle Scholar
37.Hill, H.D., Macfarlane, R.J., Senesi, A.J., Lee, B., Park, S.Y., Mirkin, C.A., Nano Lett. 8, 2341 (2008).CrossRefGoogle Scholar
38.Cheng, W., Hartman, M.R., Smilgies, D.-M., Long, R., Campolongo, M.J., Li, R., Sekar, K., Hui, C.-Y., Luo, D., Angew. Chem. Int. Ed. 49, 380 (2009).CrossRefGoogle Scholar
39.Millstone, J.E., Georganopoulou, D.G., Xu, X., Wei, W., Li, S., Mirkin, C.A., Small 4, 2176 (2008).CrossRefGoogle Scholar
40.Thaxton, C.S., Hill, H.D., Georganopoulou, D.G., Stoeva, S.I., Mirkin, C.A., Anal. Chem. 77, 8174 (2005).CrossRefGoogle Scholar
41.Stoeva, S.I., Lee, J.S., Thaxton, C.S., Mirkin, C.A., Angew. Chem. Int. Ed. 45, 3303 (2006).CrossRefGoogle Scholar
42.Nam, J.M., Thaxton, C.S., Mirkin, C.A., Science 301, 1884 (2003).CrossRefGoogle Scholar
43.Georganopoulou, D.G., Chang, L., Nam, J.M., Thaxton, C.S., Mufson, E.J., Klein, W.L., Mirkin, C.A., Proc. Nat. Acad. Sci. U.S.A. 102, 2273 (2005).CrossRefGoogle Scholar
44.Thaxton, C.S., Georganopoulou, D.G., Mirkin, C.A., Clin. Chim. Acta 363, 120 (2006).CrossRefGoogle Scholar
45.Shaikh, K.A., Ryu, K.S., Goluch, E.D., Nam, J.M., Liu, J.W., Thaxton, S., Chiesl, T.N., Barron, A.E., Lu, Y., Mirkin, C.A., Liu, C., Proc. Nat. Acad. Sci. U.S.A. 102, 9745 (2005).CrossRefGoogle Scholar
46.Thaxton, C.S., Elghanian, R., Thomas, A.D., Stoeva, S.I., Lee, J.S., Smith, N.D., Schaeffer, A.J., Klocker, H., Horninger, W., Bartsch, G., Mirkin, C.A., Proc. Nat. Acad. Sci. U.S.A. 106, 18437 (2009).CrossRefGoogle Scholar
47.Daniel, W.L., Han, M.S., Lee, J.S., Mirkin, C.A., J. Am. Chem. Soc. 131, 6362 (2009).CrossRefGoogle Scholar
48.Lee, J.S., Han, M.S., Mirkin, C.A., Angew. Chem. Int. Ed. 46, 4093 (2007).CrossRefGoogle Scholar
49.Lee, J.S., Ulmann, P.A., Han, M.S., Mirkin, C.A., Nano Lett. 8, 529 (2008).CrossRefGoogle Scholar
50.Kim, E.Y., Stanton, J., Korber, B.T.M., Krebs, K., Bogdan, D., Kunstman, K., Wu, S., Phair, J.P., Mirkin, C., Wolinsky, S.M., Nanomedicine 3, 293 (2008).CrossRefGoogle ScholarPubMed
51.Murakami, M.M., Apple, F.S., Hollander, J.E., Shipp, G.W., Clin. Chem. 55, A64 (2009).Google Scholar
52.Lv, H.T., Zhang, S.B., Wang, B., Cui, S.H., Yan, J., J. Controlled Release 114, 100 (2006).CrossRefGoogle Scholar
53.Rosi, N.L., Giljohann, D.A., Thaxton, C.S., Lytton-Jean, A.K.R., Han, M.S., Mirkin, C.A., Science 312, 1027 (2006).CrossRefGoogle Scholar
54.Giljohann, D.A., Seferos, D.S., Prigodich, A.E., Patel, P.C., Mirkin, C.A., J. Am. Chem. Soc. 131, 2072 (2009).CrossRefGoogle Scholar
55.Prigodich, A.E., Seferos, D.S., Massich, M.D., Giljohann, D.A., Lane, B.C., Mirkin, C.A., ACS Nano 3, 2147 (2009).CrossRefGoogle Scholar
56.Giljohann, D.A., Seferos, D.S., Patel, P.C., Millstone, J.E., Rosi, N.L., Mirkin, C.A., Nano Lett. 7, 3818 (2007).CrossRefGoogle Scholar
57.Seferos, D.S., Prigodich, A.E., Giljohann, D.A., Patel, P.C., Mirkin, C.A., Nano Lett. 9, 308 (2009).CrossRefGoogle Scholar
58.Massich, M.D., Giljohann, D.A., Seferos, D.S., Ludlow, L.E., Horvath, C.M., Mirkin, C.A., Mol. Pharmaceutics 6, 1934 (2009).CrossRefGoogle Scholar
59.Ryan, B.M., O'Donovan, N., Duffy, M.J., Cancer Treat. Rev. 35, 553 (2009).CrossRefGoogle Scholar
60.Wang, K.M., Tang, Z.W., Yang, C.Y.J., Kim, Y.M., Fang, X.H., Li, W., Wu, Y.R., Medley, C.D., Cao, Z., Li, J., Colon, P., Lin, H., Tan, W., Angew. Chem. Int. Ed. 48, 856 (2009).CrossRefGoogle Scholar
61.Zheng, D., Seferos, D.S., Giljohann, D.A., Patel, P.C., Mirkin, C.A., Nano Lett. 9, 3258 (2009).CrossRefGoogle Scholar
62.Yaghi, O.M., O'Keeffe, M., Ockwig, N.W., Chae, H.K., Eddaoudi, M., Kim, J., Nature 423, 705 (2003).CrossRefGoogle Scholar
63.Macfarlane, R.J., Jones, M.R., Senesi, A.J., Young, K.Y., Lee, B., Mirkin, C.A., Angew. Chem. Int. Ed. 49, 4589 (2010).CrossRefGoogle Scholar
64.Xu, X.-Y., Rosi, N.L., Wang, Y., Huo, F., Mirkin, C.A., J. Am. Chem. Soc., 128, 9286 (2006).CrossRefGoogle Scholar
65.Huo, F., Lytton-Jean, A.K.R., Mirkin, C.A., Adv. Mater. 18, 2304 (2006).CrossRefGoogle Scholar
66.Thaxton, C.S., Elghanian, R., Thomas, A.D., Stoeva, S.I., Lee, J.-S., Smith, N.D., Schaeffer, A.J., Klocker, H., Horninger, W., Bartsch, G., Mirkin, C.A., Proc. Natl. Acad. Sci., 2010, in press.Google Scholar