Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-08T00:30:15.480Z Has data issue: false hasContentIssue false
  • English
  • Français

Cell-Sheet Engineering Using Intelligent Surfaces

Published online by Cambridge University Press:  31 January 2011

Joseph Yang ,
Masayuki Yamato  and
Teruo Okano
Get access

Abstract

The possibility of recreating various tissues and organs for the purpose of regenerative medicine has received much interest. However, the field of tissue engineering has been restricted by the limitations of conventional approaches. A method to circumvent the need for traditional scaffold-based technologies is cell-sheet engineering, which uses temperature-responsive culture dishes. These surfaces, which are created by grafting the temperature-responsive polymer poly(N-isopropylacrylamide) onto ordinary culture dishes, enable the non-invasive harvesting of cells as intact sheets by simple temperature reduction. This article reviews current research on the applications of cell-sheet engineering for the reconstruction of various tissues, as well as the intelligent surfaces used by this novel technology.

Keywords

cell-sheet engineeringintelligent surfacesregenerative medicinetemperature-responsive polymertissue engineering
Type
Research Article
Information
MRS Bulletin , Volume 30 , Issue 3: Biointerface Science , March 2005 , pp. 189 - 193
Copyright
Copyright © Materials Research Society 2005

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Vacanti, J.P., Arch. Surg. 123 (1988) p. 545.Google Scholar
2.Langer, R. and Vacanti, J.P., Science 260 (1993) p. 920.Google Scholar
3.Vacanti, J.P. and Langer, R., Lancet 354 (Suppl. 1) (1999) p. SI32.CrossRefGoogle Scholar
4.Shinoka, T., Breuer, C.K., Tanel, R.E., Zund, G., Miura, T., Ma, P.X., Langer, R., Vacanti, J.P., and Mayer, J.E. Jr., Ann. Thorac. Surg. 60 (1995) p. S513.CrossRefGoogle Scholar
5.Puelacher, W.C., Vacanti, J.P., Ferraro, N.F., Schloo, B., and Vacanti, C.A., Int. J. Oral Maxillofac. Surg. 25 (1996) p. 223.Google Scholar
6.Vacanti, C.A., Langer, R., Schloo, B., and Vacanti, J.P., Plast. Reconstr. Surg. 88 (1991) p. 753.CrossRefGoogle Scholar
7.Cao, Y., Vacanti, J.P., Paige, K.T., Upton, J., and Vacanti, C.A., Plast. Reconstr. Surg. 100 (1997) p. 297.CrossRefGoogle Scholar
8.Yamada, N., Okano, T., Sakai, H., Karikusa, F., Sawasaki, Y., and Sakurai, Y., Makromol. Chem. Rapid Commun. 11 (1990) p. 571.Google Scholar
9.Okano, T., Yamada, N., Sakai, H., and Sakurai, Y., J. Biomed. Mater. Res. 27 (1993) p. 1243.Google Scholar
10.Kushida, A., Yamato, M., Konno, C., Kikuchi, A., Sakurai, Y., and Okano, T., J. Biomed. Mater. Res. 45 (1999) p. 355.3.0.CO;2-7>CrossRefGoogle Scholar
11.Hirose, M., Kwon, O.H., Yamato, M., Kikuchi, A., and Okano, T., Biomacromolecules 1 (2000) p. 377.Google Scholar
12.Nandkumar, M.A., Yamato, M., Kushida, A., Konno, C., Hirose, M., Kikuchi, A., and Okano, T., Biomaterials 23 (2002) p. 1121.CrossRefGoogle Scholar
13.Harimoto, M., Yamato, M., Hirose, M., Takahashi, C., Isoi, Y., Kikuchi, A., and Okano, T., J. Biomed. Mater. Res. 62 (2002) p. 464.CrossRefGoogle Scholar
14.Shimizu, T., Yamato, M., Isoi, Y., Akutsu, T., Setomaru, T., Abe, K., Kikuchi, A., Umezu, M., and Okano, T., Circ. Res. 90 (2002) p. e40.CrossRefGoogle Scholar
15.Nishida, K., Yamato, M., Hayashida, Y., Watanabe, K., Maeda, N., Watanabe, H., Yamamoto, K., Nagai, S., Kikuchi, A., Tano, Y., and Okano, T., Transplantation 77 (2004) p. 379.Google Scholar
16.Nishida, K., Yamato, M., Hayashida, Y., Watanabe, K., Yamamoto, K., Adachi, E., Nagai, S., Kikuchi, A., Maeda, N., Watanabe, H., Okano, T., and Tano, Y., N. Engl. J. Med. 351 (2004) p. 1187.CrossRefGoogle Scholar
17.Shiroyanagi, Y., Yamato, M., Yamazaki, Y., Toma, H., and Okano, T., BJU Int. (2004) p. 1069.Google Scholar
18.Hasegawa, M., Yamato, M., Kikuchi, A., Okano, T., and Ishikawa, I., Tissue Eng. (2005) in press.Google Scholar
19.Yamato, M., Utsumi, M., Kushida, A., Konno, C., Kikuchi, A., and Okano, T., Tissue Eng. 7 (2001) p. 473.Google Scholar
20.Mergeurian, P., Chavez, D.R., and Hakim, S., J. Urol. 152 (1994) p. 671.CrossRefGoogle Scholar
21.Aktug, T., Ozdemir, T., Agartan, C., Ozer, E., Olguner, M., and Akgur, F.M., J. Urol. 165 (2001) p. 2055.Google Scholar
22.Shiroyanagi, Y., Yamato, M., Yamazaki, Y., Toma, H., and Okano, T., Tissue Eng. 9 (2003) p. 1005.CrossRefGoogle Scholar
23.Ebara, M., Yamato, M., Aoyagi, T., Kikuchi, A., Sakai, K., and Okano, T., Biomacromolecules 5 (2004) p. 505.Google Scholar
24.Ebara, M., Yamato, M., Aoyagi, T., Kikuchi, A., Sakai, K., and Okano, T., Tissue Eng. 10 (2004) p. 1125.Google Scholar
25.Yamato, M., Konno, C., Utsumi, M., Kikuchi, A., and Okano, T., Biomaterials 23 (2002) p. 561.Google Scholar
26.Yamato, M., Kwon, O.H., Hirose, M., Kikuchi, A., and Okano, T., J. Biomed. Mater. Res. 55 (2001) p. 137.3.0.CO;2-L>CrossRefGoogle Scholar
27.Tsuda, Y., Kikuchi, A., Yamato, M., Sakurai, Y., Umezu, M., and Okano, T., J. Biomed. Mater. Res. 69A (2004) p. 70.Google Scholar