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Biomedical applications of mesoscale magnetic particles

Published online by Cambridge University Press:  13 November 2013

Bettina Kozissnik  and
Jon Dobson
Bettina Kozissnik
Affiliation:
University of Florida, Gainesville, USA; [email protected]
Jon Dobson
Affiliation:
University of Florida, Gainesville, USA; [email protected]
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Abstract

Mesoscale (nanometers to microns) magnetic particles are becoming increasingly important in biomedical applications both in vitro for cell and tissue-based research and in vivo for clinical imaging and therapy. These applications generally rely on the fact that, while the body is relatively transparent to magnetic fields, magnetic particles within the body, or in ex vivo biological samples, will couple strongly to applied external fields. By synthesizing bio-functionalized, biocompatible polymer/magnetic particle composites, this remote coupling provides a mechanism for the precisely targeted actuation of cell signaling pathways, delivery of genes, targeted transmission of thermal energy, generation of tissue matrix, and imaging (via magnetic resonance imaging), among others. This article explores a variety of biomedical applications of mesoscale magnetic particles, some of which are routinely used in the clinic and in biomedical laboratories, with others approaching the realm of science fiction.

Keywords

nanoscaleoxideferromagneticmagnetic propertiesmagnetic
Type
Magnetic Nanoparticles
Information
MRS Bulletin , Volume 38 , Issue 11: Magnetic Nanoparticles , November 2013 , pp. 927 - 932
Copyright
Copyright © Materials Research Society 2013 

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