Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-12-01T00:17:39.110Z Has data issue: false hasContentIssue false
  • English
  • Français

Material considerations for peripheral nerve interfacing

Published online by Cambridge University Press:  08 June 2012

Young-tae Kim  and
Mario I. Romero-Ortega
Young-tae Kim
Affiliation:
University or Texas at Arlington/U.T. Southwestern Medical Center, Arlington, TX 76019, USA; [email protected]
Mario I. Romero-Ortega
Affiliation:
Bioengineering Department, University of Texas at Arlington/U.T. Southwestern Medical Center, Arlington, TX 76019, USA; [email protected]
Get access

Abstract

Multi-fingered prosthetic limbs are now capable of performing complex movements, closely simulating those of the lost human arm/hand in amputees. Conveying natural control and perception of such sophisticated robotic limbs requires direct interfacing with the nervous system of the users. Both the brain and transected peripheral nerves have been proposed as appropriate locations for such neural interfaces. In the peripheral nerves, several electrode designs have been used successfully to record motor signals, and through stimulation, used to convey sensation in long-term amputee human volunteers. Here we review the advantages and limitations of peripheral nerve interfaces (PNIs) in relation to the desired characteristics for safety and performance. We compare current PNI electrodes and materials designed to increase recording sensitivity and to achieve selective stimulation of different nerves such as those carrying mechanical sensation and limb position information. Emphasis is placed on novel electrode materials, including biological coatings, conductive polymers, and nanostructured modifications. Successful development of reliable PNIs will not only enable natural control and feel of future robotic prosthetics, but will likely be a centerpiece technology in the development of multiple bionic organs.

Type
Research Article
Information
MRS Bulletin , Volume 37 , Issue 6: Materials for neural interfaces , June 2012 , pp. 573 - 580
Copyright
Copyright © Materials Research Society 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Carpaneto, J., Micera, S., Zaccone, F., Vecchi, F., Dario, P., IEEE Trans. Neural Syst. Rehabil. Eng. 11, 346 (2003).CrossRefGoogle Scholar
2.Cipriani, C., Controzzi, M., Carrozza, M.C., J. Neuroeng. Rehabil. 8, 29 (2011).CrossRefGoogle Scholar
3.Uellendahl, J.E., Phys. Med. Rehabil. Clin. N. Am. 11, 639 (2000).CrossRefGoogle Scholar
4.Farrell, T.R., Weir, R.F., IEEE Trans. Neural Syst. Rehabil. Eng. 15, 111 (2007).CrossRefGoogle Scholar
5.Kuiken, T.A., Li, G., Lock, B.A., Lipschutz, R.D., Miller, L.A., Stubblefield, K.A., Englehart, K.B., JAMA 301, 619 (2009).CrossRefGoogle Scholar
6.Marasco, P.D., Kuiken, T.A., J. Neurosci. 30, 16008 (2010).CrossRefGoogle Scholar
7.Chapin, J.K., Moxon, K.A., Markowitz, R.S., Nicolelis, M.A., Nat. Neurosci. 2, 664 (1999).CrossRefGoogle Scholar
8.Schwartz, A.B., Cui, X.T., Weber, D.J., Moran, D.W., Neuron 52, 205 (2006).CrossRefGoogle Scholar
9.Simeral, J.D., Kim, S.P., Black, M.J., Donoghue, J.P., Hochberg, L.R., J. Neural Eng. 8, 025027 (2011).CrossRefGoogle Scholar
10.Hochberg, L.R., Serruya, M.D., Friehs, G.M., Mukand, J.A., Saleh, M., Caplan, A.H., Branner, A., Chen, D., Penn, R.D., Donoghue, J.P., Nature 442, 164 (2006).CrossRefGoogle Scholar
11.Fitzsimmons, N.A., Drake, W., Hanson, T.L., Lebedev, M.A., Nicolelis, M.A., J. Neurosci. 27, 5593 (2007).CrossRefGoogle Scholar
12.Brown, P.B., Koerber, H.R., Millecchia, R., Brain Res. 1011, 14 (2004).CrossRefGoogle Scholar
13.Lee, S., Carvell, G.E., Simons, D.J., Nat. Neurosci. 11, 1430 (2008).CrossRefGoogle Scholar
14.Grill, W.M., Norman, S.E., Bellamkonda, R.V., Annu. Rev. Biomed. Eng. 11, 1 (2009).CrossRefGoogle Scholar
15.Hatsopoulos, N.G., Donoghue, J.P., Annu. Rev. Neurosci. 32, 249 (2009).CrossRefGoogle Scholar
16.Gilja, V., Chestek, C.A., Diester, I., Henderson, J.M., Deisseroth, K., Shenoy, K.V., IEEE Trans. Biomed. Eng. 58, 1891 (2011).CrossRefGoogle Scholar
17.Naples, G.G., Mortimer, J.T., Scheiner, A., Sweeney, J.D., IEEE Trans. Biomed. Eng. 35, 905 (1988).CrossRefGoogle Scholar
18.Rodríguez, F.J., Ceballos, D., Schüttler, M., Valero, A., Valderrama, E., Stieglitz, T., Navarro, X., J. Neurosci. Methods 98, 105 (2000).CrossRefGoogle Scholar
19.Shain, W., Spataro, L., Dilgen, J., Haverstick, K., Retterer, S., Isaacson, M., Saltzman, M., Turner, J.N., IEEE Trans. Neural Syst. Rehabil. Eng. 11, 186 (2003).CrossRefGoogle Scholar
20.Rabischong, B., Larrain, D., Rabischong, P., Botchorishvili, R., Fraisse, G., Gallego, S., Gaydier, P., Chardigny, J.M., Avan, P., Surg. Endosc. 25, 3706 (2011).CrossRefGoogle Scholar
21.Tyler, D.J., Durand, D.M., IEEE Trans. Neural Syst. Rehabil. Eng. 10, 294 (2002).CrossRefGoogle Scholar
22.Fisher, L.E., Tyler, D.J., Anderson, J.S., Triolo, R.J., J. Neural Eng. 6, 046010 (2009).CrossRefGoogle Scholar
23.Vince, V., Brelen, M.E., Delbeke, J., Colin, I.M., J. Neuroimmunol. 165, 121 (2005).CrossRefGoogle Scholar
24.Wodlinger, B., Durand, D.M., IEEE Trans. Neural Syst. Rehabil. Eng. 17, 461 (2009).CrossRefGoogle Scholar
25.Durand, D., Park, H.J., Wodlinger, B., Conf. Proc. IEEE Eng. Med. Biol. Soc. 1, 3326 (2009).Google Scholar
26.Weber, D.J., Stein, R.B., Everaert, D.G., Prochazka, A., J. Neural Eng. 4, S168 (2007).CrossRefGoogle Scholar
27.Gaunt, R.A., Hokanson, J.A., Weber, D.J., J. Neural Eng. 6, 55009 (2009).CrossRefGoogle Scholar
28.Dhillon, G.S., Lawrence, S.M., Hutchinson, D.T., Horch, K.W., J. Hand Surg. Am. 29, 605; discussion 616 (2004).CrossRefGoogle Scholar
29.Dhillon, G.S., Horch, K.W., IEEE Trans. Neural Syst. Rehabil. Eng. 13, 468 (2005).CrossRefGoogle Scholar
30.Rossini, P.M., Micera, S., Benvenuto, A., Carpaneto, J., Cavallo, G., Citi, L., Cipriani, C., Denaro, L., Denaro, V., Di Pino, G., Ferreri, F., Guglielmelli, E., Hoffmann, K.P., Raspopovic, S., Rigosa, J., Rossini, L., Tombini, M., Dario, P., Clin. Neurophysiol. 121, 777 (2010).CrossRefGoogle Scholar
31.Navarro, X., Krueger, T.B., Lago, N., Micera, S., Stieglitz, T., Dario, P., J. Peripher. Nerv. Syst. 10, 229 (2005).CrossRefGoogle Scholar
32.Lefurge, T., Goodall, E., Horch, K., Stensaas, L., Schoenberg, A., Ann. Biomed. Eng. 19, 197 (1991).CrossRefGoogle Scholar
33.Malmstrom, J.A., McNaughton, T.G., Horch, K.W., Ann. Biomed. Eng. 26, 1055 (1998).CrossRefGoogle Scholar
34.McNaughton, T.G., Horch, K.W., J. Neurosci. Methods 70, 103 (1996).CrossRefGoogle Scholar
35.Lawrence, S.M., Dhillon, G.S., Jensen, W., Yoshida, K., Horch, K.W., IEEE Trans. Neural Syst. Rehabil. Eng. 12, 345 (2004).CrossRefGoogle Scholar
36.Lago, N., Yoshida, K., Koch, K.P., Navarro, X., IEEE Trans. Biomed. Eng. 54, 281 (2007).CrossRefGoogle Scholar
37.Lago, N., Navarro, X., J. Peripher. Nerv. Syst. 12, 108 (2007).CrossRefGoogle Scholar
38.Lago, N., Udina, E., Ramachandran, A., Navarro, X., IEEE Trans. Biomed. Eng. 54, 1129 (2007).CrossRefGoogle Scholar
39.Boretius, T., Badia, J., Pascual-Font, A., Schuettler, M., Navarro, X., Yoshida, K., Stieglitz, T., Biosens. Bioelectron. 26, 62 (2010).CrossRefGoogle Scholar
40.Bowman, B.R., Erickson, R.C., Ann. Biomed. Eng. 13, 75 (1985).CrossRefGoogle Scholar
41.Branner, A., Normann, R.A., Brain Res. Bull. 51, 293 (2000).CrossRefGoogle Scholar
42.Branner, A., Stein, R.B., Fernandez, E., Aoyagi, Y., Normann, R.A., IEEE Trans. Biomed. Eng. 51, 146 (2004).CrossRefGoogle Scholar
43.Edell, D.J., Churchill, J.N., Gourley, I.M., Biomater. Med. Devices Artif. Organs 10, 103 (1982).CrossRefGoogle Scholar
44.Mannard, A., Stein, R.B., Charles, D., Science 183, 547 (1974).CrossRefGoogle Scholar
45.Akin, T., Najafi, K., Smoke, R.H., Bradley, R.M., IEEE Trans. Biomed. Eng. 41, 305 (1994).CrossRefGoogle Scholar
46.Wallman, L., Zhang, Y., Laurell, T., Danielsen, N., Biomaterials 22, 1187 (2001).CrossRefGoogle Scholar
47.Bradley, R.M., Cao, X., Akin, T., Najafi, K., J. Neurosci. Methods 73, 177 (1997).CrossRefGoogle Scholar
48.Kovacs, G.T., Storment, C.W., Rosen, J.M., IEEE Trans. Biomed. Eng. 39, 893 (1992).CrossRefGoogle Scholar
49.Ramachandran, A., Schuettler, M., Lago, N., Doerge, T., Koch, K.P., Navarro, X., Hoffmann, K.P., Stieglitz, T., J. Neural Eng. 3, 114 (2006).CrossRefGoogle Scholar
50.Navarro, X., Calvet, S., Rodriguez, F.J., Stieglitz, T., Blau, C., Buti, M., Valderrama, E., Meyer, J.U., J. Peripher. Nerv. Syst. 3, 91 (1998).Google Scholar
51.Lago, N., Ceballos, D., Rodriguez, F.J., Stieglitz, T., Navarro, X., Biomaterials 26, 2021 (2005).CrossRefGoogle Scholar
52.Castro, J., Negredo, P., Avendano, C., Brain Res. 1190, 65 (2008).CrossRefGoogle Scholar
53.Garde, K., Keefer, E., Botterman, B., Galvan, P., Romero, M.I., Front Neuroeng. 2, 5 (2009).CrossRefGoogle Scholar
54.Lacour, S.P., Atta, R., Fitzgerald, J., Blamire, M., Tarte, E., Fawcett, J., Sens. Actuators, A 147, 456 (2008).CrossRefGoogle Scholar
55.Srinivasan, A., Guo, L., Bellamkonda, R.V., Conf. Proc. IEEE Eng. Med. Biol. Soc. 2011, 253 (2011).Google Scholar
56.Merrill, D.R., Bikson, M., Jefferys, J.G., J. Neurosci. Methods 141, 171 (2005).CrossRefGoogle Scholar
57.Grill, W.M., in Indwelling Neural Implants, Reichert, W.M., Ed. (CRC Press, Boca Raton, FL, 2008).Google Scholar
58.Jan, E., Hendricks, J.L., Husaini, V., Richardson-Burns, S.M., Sereno, A., Martin, D.C., Kotov, N.A., Nano Lett. 9, 4012 (2009).CrossRefGoogle Scholar
59.Venkatraman, S., Elkabany, K., Long, J.D., Yao, Y., Carmena, J.M., IEEE Trans. Biomed. Eng. 56, 15 (2009).CrossRefGoogle Scholar
60.Mattson, M.P., Haddon, R.C., Rao, A.M., J. Mol. Neurosci. 14, 175 (2000).CrossRefGoogle Scholar
61.Galvan-Garcia, P., Keefer, E.W., Yang, F., Zhang, M., Fang, S., Zakhidov, A.A., Baughman, R.H., Romero, M.I., J. Biomater. Sci., Polym. Ed. 18, 1245 (2007).CrossRefGoogle Scholar
62.Keefer, E.W., Botterman, B.R., Romero, M.I., Rossi, A.F., Gross, G.W., Nat. Nanotechnol. 3, 434 (2008).CrossRefGoogle Scholar
63.Cellot, G., Toma, F.M., Varley, Z.K., Laishram, J., Villari, A., Quintana, M., Cipollone, S., Prato, M., Ballerini, L., L, J. Neurosci. 31, 12945 (2011).CrossRefGoogle Scholar
64.Williams, J.C., Hippensteel, J.A., Dilgen, J., Shain, W., Kipke, D.R., J. Neural Eng. 4, 410 (2007).CrossRefGoogle Scholar
65.Mercanzini, A., Colin, P., Bensadoun, J.C., Bertsch, A., Renaud, P., IEEE Trans. Biomed. Eng. 56, 1909 (2009).CrossRefGoogle Scholar
66.Vince, V., Brelen, M.E., Delbeke, J., Colin, I.M., J. Neuroimmunol. 159, 75 (2005).CrossRefGoogle Scholar
67.Winslow, B.D., Tresco, P.A., Biomaterials 31, 1558 (2010).CrossRefGoogle Scholar
68.Leung, B.K., Biran, R., Underwood, C.J., Tresco, P.A., Biomaterials 29, 3289 (2008).CrossRefGoogle ScholarPubMed
69.Biran, R., Martin, D.C., Tresco, P.A., Exp. Neurol. 195, 115 (2005).CrossRefGoogle Scholar
70.Cui, X., Lee, V.A., Raphael, Y., Wiler, J.A., Hetke, J.F., Anderson, D.J., Martin, D.C., J. Biomed. Mater. Res. 56, 261 (2001).3.0.CO;2-I>CrossRefGoogle Scholar
71.Cui, X., Wiler, J., Dzaman, M., Altschuler, R.A., Martin, D.C., Biomaterials 24, 777 (2003).CrossRefGoogle Scholar
72.Spataro, L., Dilgen, J., Retterer, S., Spence, A.J., Isaacson, M., Turner, J.N., Shain, W., Exp. Neurol. 194, 289 (2005).CrossRefGoogle Scholar
73.Zhong, Y., Bellamkonda, R.V., Brain Res. 1148, 15 (2007).CrossRefGoogle Scholar
74.Mercanzini, A., Reddy, S.T., Velluto, D., Colin, P., Maillard, A., Bensadoun, J.C., Hubbell, J. A., Renaud, P., J. Controlled Release 145, 196 (2010).CrossRefGoogle ScholarPubMed
75.Yao, G.L., Kiyama, H., Brain Res. Mol. Brain Res. 32, 308 (1995).CrossRefGoogle Scholar
76.Ignatius, M.J., Sawhney, N., Gupta, A., Thibadeau, B.M., Monteiro, O.R., Brown, I.G., J. Biomed. Mater. Res. 40, 264 (1998).3.0.CO;2-M>CrossRefGoogle Scholar
77.He, W., McConnell, G.C., Bellamkonda, R.V., J. Neural Eng. 3, 316 (2006).CrossRefGoogle Scholar
78.Bossi, S., Benvenuto, A., Wieringa, P., Di Pino, G., Guglielmelli, E., Boretius, T., Stieglitz, T., Navarro, X., Micera, S., Conf. Proc. IEEE Eng. Med. Biol. Soc. 2010, 1527 (2010).Google Scholar
79.Sorribas, H., Braun, D., Leder, L., Sonderegger, P., Tiefenauer, L., J. Neurosci. Methods 104, 133 (2001).CrossRefGoogle Scholar
80.Azemi, E., Lagenaur, C.F., Cui, X.T., Biomaterials 32, 681 (2010).CrossRefGoogle Scholar
81.Kennedy, P.R., Mirra, S.S., Bakay, R.A., Neurosci. Lett. 142, 89 (1992).CrossRefGoogle Scholar
82.Winter, J.O., Cogan, S.F., Rizzo, J.F., J. Biomed. Mater. Res. Part B 81, 551 (2007).CrossRefGoogle Scholar
83.Winter, J.O., Han, N., Jensen, R., Cogan, S.F., Rizzo, J.F., Conf. Proc. IEEE Eng. Med. Biol. Soc. 2009, 7151 (2009).Google Scholar
84.Green, R.A., Lovell, N.H., Poole-Warren, L.A., Acta Biomater. 6, 63 (2009).CrossRefGoogle Scholar
85.Huang, J., Hu, X., Lu, L., Ye, Z., Zhang, Q., Luo, Z., J. Biomed. Mater. Res. 93, 164 (2010).CrossRefGoogle Scholar
86.Romero, M.I., Rangappa, N., Garry, M.G., Smith, G.M., J. Neurosci. 21, 8408 (2001).CrossRefGoogle Scholar
87.Hu, X., Cai, J., Yang, J., Smith, G.M., Exp. Neurol. 223, 153 (2009).CrossRefGoogle Scholar
88.Phillips, C.A., Crit. Rev. Biomed. Eng. 16, 105 (1988).Google Scholar
89.Egermann, M., Kasten, P., Thomsen, M., Int. Orthop. 33, 1101 (2009).CrossRefGoogle Scholar
90.Stewart, J.D., Muscle Nerve 28, 525 (2003).CrossRefGoogle Scholar
91.Brushart, T.M., Mathur, V., Sood, R., Koschorke, G.M., J. Hand Surg. Am. 20, 557 (1995).CrossRefGoogle Scholar
92.Lertmanorat, Z., Durand, D.M., IEEE Trans. Biomed. Eng. 51, 1242 (2004).CrossRefGoogle Scholar
93.Yoshida, K., Horch, K., IEEE Trans. Biomed. Eng. 40, 492 (1993).CrossRefGoogle Scholar
94.Goodall, E.V., Lefurge, T.M., Horch, K.W., IEEE Trans. Biomed. Eng. 38, 846 (1991).CrossRefGoogle Scholar
95.Lotfi, P., Garde, K., Chouhan, A.K., Bengali, E., Romero-Ortega, M.I., Front. Neuroeng. 4, 11 (2011).CrossRefGoogle Scholar
96.Sahin, M., Haxhiu, M.A., Durand, D.M., Dreshaj, I.A., J. Appl. Physiol. 83, 317 (1997).CrossRefGoogle Scholar