Hostname: page-component-745bb68f8f-lrblm Total loading time: 0 Render date: 2025-01-07T13:27:29.833Z Has data issue: false hasContentIssue false
  • English
  • Français

3D printing of ceramic implants

Published online by Cambridge University Press:  12 February 2015

Elke Vorndran ,
Claus Moseke  and
Uwe Gbureck
Elke Vorndran
Affiliation:
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany; [email protected]
Claus Moseke
Affiliation:
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany; [email protected]
Uwe Gbureck
Affiliation:
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany; [email protected]
Get access

Abstract

Three-dimensional powder printing (3DP) is attractive for the direct fabrication of bioceramic implants and scaffolds from a computer aided design file for bone tissue engineering by localized deposition of a reactive binder liquid onto thin powder layers. This article reviews recent findings on novel material developments for the three-dimensional (3D) printing process using either sintering regimes or cement setting reactions. Customized ceramic implants can be fabricated by 3DP using computer tomography data obtained from a patient, whereas further drug modification of such implants can be achieved either in situ or post-printing. The excellent biological in vitro and in vivo behavior of 3D-printed bioceramics together with processing at ambient conditions may give the opportunity to directly produce cell-seeded patient-specific implants for accelerated and enhanced bone regeneration in the future.

Keywords

ink-jet printingceramicbonebiomaterial
Type
Research Article
Information
MRS Bulletin , Volume 40 , Issue 2: 3D printing of biomaterials , February 2015 , pp. 127 - 136
Copyright
Copyright © Materials Research Society 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Felsenberg, D., Pharm. Unserer Zeit 30, 488 (2001).Google Scholar
Aaboe, M., Pinholt, E.M., Hjorting-Hansen, E., Br. J. Oral Maxillofac. Surg. 33, 312 (1995).CrossRefGoogle Scholar
Greenwald, A.S., Boden, S.D., Goldberg, V.M., Khan, Y., Laurencin, C.T., Rosier, R.N., J. Bone Joint Surg. 83, S98 (2001).CrossRefGoogle Scholar
Jones, J.R., Lin, S., Yue, S., Lee, P.D., Hanna, J.V., Smith, M.E., Newport, R.J., Proc. Inst. Mech. Eng. H 224, 1373 (2010).Google Scholar
Keating, J.F., McQueen, M., J. Bone Joint Surg. Br. 83, 3 (2001).Google Scholar
Eufinger, H., Wittkampf, A.R.M., Wehmöller, M., Zonneveld, F.W., J. Cranio-Maxillofac. Surg. 26, 373 (1998).Google Scholar
Siebert, H., Schleier, P., Beinemann, J., Fried, W., Zenk, W., Schumann, D., Mund Kiefer Gesichtschir. 10, 185 (2006).CrossRefGoogle Scholar
Scolozzi, P., Martinez, A., Jaques, B., J. Craniofac. Surg. 18, 224 (2007).CrossRefGoogle Scholar
Bohner, M., Mater. Today 13, 24 (2010).CrossRefGoogle Scholar
Eufinger, H., Wehmöller, M., Machtens, E., Heuser, L., Harders, A., Kruse, D., J. Cranio-Maxillofac. Surg. 23, 175 (1995).Google Scholar
Eufinger, H., Rasche, C., Lehmbrock, J., Wehmöller, M., Weihe, S., Schmitz, I., Schiller, C., Epple, M., Biomaterials 28, 475 (2007).CrossRefGoogle Scholar
Weihe, S., Wehmöller, M., Schliephake, H., Haßfeld, S., Tschakaloff, A., Raczkowsky, J., Eufinger, H., Int. J. Oral Maxillofac. Surg. 29, 384 (2000).Google Scholar
Darsell, J., Bose, S., Hosick, H.L., Bandyopadhyay, A., J. Am. Ceram. Soc. 86, 1076 (2003).CrossRefGoogle Scholar
Hutmacher, D.W., Biomaterials 21, 2529 (2000).CrossRefGoogle Scholar
Hutmacher, D.W., J. Biomater. Sci. Polym. Ed. 12, 107 (2001).CrossRefGoogle Scholar
Sadeghian, Z., Heinrich, J.G., Moztarzadeh, F., CFI Ceram. Forum Int. 81, E39 (2004).Google Scholar
Wilson, C.E., de Bruijn, J.D., van Blitterswijk, C.A., Verbout, A.J., Dhert, W.J.A., J. Biomed. Mater. Res. Part A 68A, 123 (2004).CrossRefGoogle Scholar
Jafari, M.A., Han, W., Mohammadi, F., Safari, A., Danforth, S.C., Langrana, N., Rapid Prototyp. J. 6, 161 (2000).CrossRefGoogle Scholar
Kalita, S.J., Bose, S., Hosick, H.L., Bandyopadhyay, A., Mater. Sci. Eng. C 23, 611 (2003).CrossRefGoogle Scholar
Teo, E.Y., Ong, S.-Y., Khoon Chong, M.S., Zhang, Z., Lu, J., Moochhala, S., Ho, B., Teoh, S.-H., Biomaterials 32, 279 (2011).Google Scholar
Griffith, M.L., Halloran, J.W., J. Am. Ceram. Soc. 79, 2601 (1996).CrossRefGoogle Scholar
Melchels, F.P.W., Feijen, J., Grijpma, D.W., Biomaterials 31, 6121 (2010).CrossRefGoogle Scholar
Sachs, E.M., Haggerty, J.S., Cima, M.J., Williams, P.A., US Patent 5204055 A (April 20, 1993).Google Scholar
Jackson, T.R., Liu, H., Patrikalakis, N.M., Sachs, E.M., Cima, M.J., Mater. Des. 20, 63 (1999).CrossRefGoogle Scholar
Butscher, A., Bohner, M., Hofmann, S., Gauckler, L., Müller, R., Acta Biomater. 7, 907 (2011).CrossRefGoogle Scholar
Lu, K., Reynolds, W.T., Powder Technol. 187, 11 (2008).Google Scholar
Chandrasekaran, M., Lim, K., Lee, M., Cheang, P., Singap. Inst. Manuf. Technol. (SIMTech) Tech. Rep. 8, 1 (2007).Google Scholar
Leukers, B., Gülkan, H., Irsen, S.H., Milz, S., Tille, C., Schieker, M., Seitz, H., J. Mater. Sci. Mater. Med. 16, 1121 (2005).CrossRefGoogle Scholar
Warnke, P.H., Seitz, H., Warnke, F., Becker, S.T., Sivananthan, S., Sherry, E., Liu, Q., Wiltfang, J., Douglas, T., J. Biomed. Mater. Res. Part B 93B, 212 (2010).CrossRefGoogle Scholar
Suwanprateeb, J., Kerdsook, S., Boonsiri, T., Pratumpong, P., Polym. Int. 60, 758 (2011).Google Scholar
Suwanprateeb, J., Chumnanklang, R., J. Biomed. Mater. Res. Part B 78B, 138 (2006).CrossRefGoogle Scholar
Suwanprateeb, J., Sanngam, R., Suwanpreuk, W., J. Mater. Sci. Mater. Med. 19, 2637 (2008).Google Scholar
Sachs, E., US Patent, 6036777 A (March 14, 2000).Google Scholar
Tay, B.Y., Evans, J.R.G., Edirisinghe, M.J., Int. Mater. Rev. 48, 341 (2003).Google Scholar
Butscher, A., Bohner, M., Roth, C., Ernstberger, A., Heuberger, R., Doebelin, N., Rudolf von Rohr, P., Müller, R., Acta Biomater. 8, 373 (2012).CrossRefGoogle Scholar
Castilho, M., Moseke, C., Ewald, A., Gbureck, U., Groll, J., Pires, I., Teßmar, J., Vorndran, E., Biofabrication 6, 015006 (2014).Google Scholar
Gbureck, U., Hölzel, T., Doillon, C.J., Müller, F.A., Barralet, J.E., Adv. Mater. 19, 795 (2007).CrossRefGoogle Scholar
Vorndran, E., Klarner, M., Klammert, U., Grover, L.M., Patel, S., Barralet, J.E., Gbureck, U., Adv. Eng. Mater. 10, B67 (2008).Google Scholar
Gbureck, U., Hölzel, T., Klammert, U., Würzler, K., Müller, F.A., Barralet, J.E., Adv. Funct. Mater. 17, 3940 (2007).Google Scholar
Pfister, A., Walz, U., Laib, A., Mülhaupt, R., Macromol. Mater. Eng. 290, 99 (2005).CrossRefGoogle Scholar
Klammert, U., Vorndran, E., Reuther, T., Müller, F.A., Zorn, K., Gbureck, U., J. Mater. Sci. Mater. Med. 21, 2947 (2010).Google Scholar
Maier, A.-K., Dezmirean, L., Will, J., Greil, P., J. Mater. Sci. 46, 2947 (2011).CrossRefGoogle Scholar
Gibbons, G.J., Williams, R., Purnell, P., Farahi, E., Adv. Appl. Ceram. 109, 287 (2010).Google Scholar
Gbureck, U., Hölzel, T., Biermann, I., Barralet, J.E., Grover, L.M., J. Mater. Sci. Mater. Med. 19, 1559 (2008).Google Scholar
Vorndran, E., Wunder, K., Moseke, C., Biermann, I., Müller, F.A., Zorn, K., Gbureck, U., Adv. Appl. Ceram. 110, 476 (2011).Google Scholar
Gbureck, U., Hölzel, T., Thull, R., Müller, F.A., Barralet, J.E., Cytotherapy 8, 14 (2006).Google Scholar
Suwanprateeb, J., Suvannapruk, W., Wasoontararat, K., J. Mater. Sci. Mater. Med. 21, 419 (2010).Google Scholar
Vorndran, E., thesis, Würzburg, Germany (2011).Google Scholar
Kanter, B., Geffers, M., Ignatius, A., Gbureck, U., Acta Biomater. 10, 3279 (2014).Google Scholar
Klammert, U., Böhm, H., Schweitzer, T., Würzler, K., Gbureck, U., Reuther, J., Kübler, A., J. Cranio-Maxillofac. Surg. 37, 210 (2009).Google Scholar
Klammert, U., Gbureck, U., Vorndran, E., Rödiger, J., Meyer-Marcotty, P., Kübler, A.C., J. Cranio-Maxillofac. Surg. 38, 565 (2010).Google Scholar
Khalyfa, A., Vogt, S., Weisser, J., Grimm, G., Rechtenbach, A., Meyer, W., Schnabelrauch, M., J. Mater. Sci. Mater. Med. 18, 909 (2007).Google Scholar
Zhim, F., Ayers, R.A., Moore, J.J., Moufarrège, R., Yahia, L., J. Biomater. Appl. 27, 323 (2012).Google Scholar
Tarafder, S., Dernell, W.S., Bandyopadhyay, A., Bose, S., J. Biomed. Mater. Res. Part B (2014), doi: 10.1002/jbm.b.33239.Google Scholar
Tarafder, S., Davies, N.M., Bandyopadhyay, A., Bose, S., Biomater. Sci. 1, 1250 (2013).CrossRefGoogle Scholar
Tarafder, S., Balla, V.K., Davies, N.M., Bandyopadhyay, A., Bose, S., J. Tissue Eng. Regen. Med. 7, 631 (2013).Google Scholar
Bose, S., Roy, M., Bandyopadhyay, A., Trends Biotechnol. 30, 546 (2012).Google Scholar
Fielding, G., Bose, S., Acta Biomater. 9, 9137 (2013).Google Scholar
Detsch, R., Schaefer, S., Deisinger, U., Ziegler, G., Seitz, H., Leukers, B., J. Biomater. Appl. 26, 359 (2010).CrossRefGoogle Scholar
Klammert, U., Reuther, T., Jahn, C., Kraski, B., Kübler, A.C., Gbureck, U., Acta Biomater. 5, 727 (2009).Google Scholar
Habibovic, P., Gbureck, U., Doillon, C.J., Bassett, D.C., van Blitterswijk, C.A., Barralet, J.E., Biomaterials 29, 944 (2008).Google Scholar
Inzana, J.A., Olvera, D., Fuller, S.M., Kelly, J.P., Graeve, O.A., Schwarz, E.M., Kates, S.L., Awad, H.A., Biomaterials 35, 4026 (2014).Google Scholar
Holzapfel, B.M., Reichert, J.C., Schantz, J.-T., Gbureck, U., Rackwitz, L., Nöth, U., Jakob, F., Rudert, M., Groll, J., Hutmacher, D.W., Adv. Drug Deliv. Rev. 65, 581 (2013).Google Scholar
Alkhraisat, M.H., Rueda, C., Jerez, L.B., Tamimi Mariño, F., Torres, J., Gbureck, U., López-Cabarcos, E., Acta Biomater. 6, 257 (2010).Google Scholar
Tamimi, F., Torres, J., Gbureck, U., López-Cabarcos, E., Bassett, D.C., Alkhraisat, M.H., Barralet, J.E., Biomaterials 30, 6318 (2009).Google Scholar
Torres, J., Tamimi, F., Alkhraisat, M.H., Prados-Frutos, J.C., Rastikerdar, E., Gbureck, U., Barralet, J.E., López-Cabarcos, E., J. Clin. Periodontol. 38, 1147 (2011).Google Scholar
Tamimi, F., Torres, J., Al-Abedalla, K., López-Cabarcos, E., Alkhraisat, M.H., Bassett, D.C., Gbureck, U., Barralet, J.E., Biomaterials 35, 5436 (2014).Google Scholar
Arcos, D., Vallet-Regí, M., Acta Mater. 61, 890 (2013).Google Scholar
Barralet, J., Gbureck, U., Habibovic, P., Vorndran, E., Gerard, C., Doillon, C.J., Tissue Eng. Part A 15, 1601 (2009).Google Scholar
Sudo, A., Hasegawa, M., Fukuda, A., Uchida, A., J. Arthroplasty 23, 145 (2008).Google Scholar
Uchida, A., Shinto, Y., Araki, N., Ono, K., J. Orthop. Res. 10, 440 (1992).Google Scholar
Wu, P., Grainger, D.W., Biomaterials 27, 2450 (2006).Google Scholar
Gbureck, U., Vorndran, E., Müller, F.A., Barralet, J.E., J. Control. Release 122, 173 (2007).Google Scholar
Cornelsen, M., Petersen, S., Dietsch, K., Rudolph, A., Schmitz, K., Sternberg, K., Seitz, H., Biomed. Tech. 58 (Suppl. 1) (2013).Google Scholar
Becker, S.T., Bolte, H., Schünemann, K., Seitz, H., Bara, J.J., Beck-Broichsitter, B.E., Russo, P.A.J., Wiltfang, J., Warnke, P.H., Int. J. Oral Maxillofac. Surg. 41, 1153 (2012).Google Scholar
Tarafder, S., Bose, S., ACS Appl. Mater. Interfaces 6, 9955 (2014).CrossRefGoogle Scholar
Tarafder, S., Nansen, K., Bose, S., Mater. Sci. Eng. C 33, 3121 (2013).Google Scholar
Saylor, D.M., Kim, C.-S., Patwardhan, D.V., Warren, J.A., J. Pharm. Sci. 98, 169 (2009).Google Scholar
Sandler, N., Määttänen, A., Ihalainen, P., Kronberg, L., Meierjohann, A., Viitala, T., Peltonen, J., J. Pharm. Sci. 100, 3386 (2011).CrossRefGoogle Scholar
Wu, B.M., Borland, S.W., Giordano, R.A., Cima, L.G., Sachs, E.M., Cima, M.J., J. Control. Release 40, 77 (1996).Google Scholar
Katstra, W.E., Palazzolo, R.D., Rowe, C.W., Giritlioglu, B., Teung, P., Cima, M.J., J. Control. Release 66, 1 (2000).Google Scholar
Wu, W., Zheng, Q., Guo, X., Huang, W., J. Wuhan Univ. Technol. Mater. Sci. Ed. 24, 977 (2009).Google Scholar
Yu, D.G., Zhu, L.-M., Branford-White, C.J., Yang, X.L., J. Pharm. Sci. 97, 3666 (2008).Google Scholar
Yu, D.G., Yang, X.L., Huang, W.D., Liu, J., Wang, Y.G., Xu, H., J. Pharm. Sci. 96, 2446 (2007).Google Scholar
Wu, W., Zheng, Q., Guo, X., Sun, J., Liu, Y., Biomed. Mater. 4, 065005 (2009).Google Scholar
Yu, D.-G., Branford-White, C., Ma, Z.-H., Zhu, L.-M., Li, X.-Y., Yang, X.-L., Int. J. Pharm. 370, 160 (2009).Google Scholar
Vorndran, E., Klammert, U., Ewald, A., Barralet, J.E., Gbureck, U., Adv. Funct. Mater. 20, 1585 (2010).Google Scholar
Wilson, W.C., Boland, T., Anat. Rec. A. Discov. Mol. Cell. Evol. Biol. 272A, 491 (2003).Google Scholar
Xu, T., Gregory, C.A., Molnar, P., Cui, X., Jalota, S., Bhaduri, S.B., Boland, T., Biomaterials 27, 3580 (2006).Google Scholar
Xu, T., Jin, J., Gregory, C., Hickman, J.J., Boland, T., Biomaterials 26, 93 (2005).Google Scholar
Boland, T., Xu, T., Damon, B., Cui, X., Biotechnol. J. 1, 910 (2006).Google Scholar
Weir, M.D., Xu, H.H.K., Simon, C.G., J. Biomed. Mater. Res. Part A 77A, 487 (2006).Google Scholar
Will, J., Melcher, R., Treul, C., Travitzky, N., Kneser, U., Polykandriotis, E., Horch, R., Greil, P., J. Mater. Sci. Mater. Med. 19, 2781 (2008).Google Scholar
Suwanprateeb, J., Sanngam, R., Panyathanmaporn, T., Mater. Sci. Eng. C 30, 610 (2010).Google Scholar
Seitz, H., Deisinger, U., Leukers, B., Detsch, R., Ziegler, G., Adv. Eng. Mater. 11, B41 (2009).Google Scholar
Fielding, G.A., Bandyopadhyay, A., Bose, S., Dent. Mater. 28, 113 (2012).Google Scholar
Bergmann, C., Lindner, M., Zhang, W., Koczur, K., Kirsten, A., Telle, R., Fischer, H., J. Eur. Ceram. Soc. 30, 2563 (2010).CrossRefGoogle Scholar
Meszaros, R., Zhao, R., Travitzky, N., Fey, T., Greil, P., Wondraczek, L., Glass Technol.: Eur. J. Glass Sci. Technol. Part A 52, 111 (2011).Google Scholar