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Mécanique des systémes précontraints appliquée à la structure du cytosquelette

Published online by Cambridge University Press:  05 August 2009

Patrick Cañadas ,
Bernard Maurin  and
René Motro
Patrick Cañadas
Affiliation:
Université Montpellier 2 – Laboratoire de Mécanique et Génie Civil (LMGC) UMR 5508 CNRS – Place Eugène Bataillon, CC048, 34095 Montpellier, France
Bernard Maurin
Affiliation:
Université Montpellier 2 – Laboratoire de Mécanique et Génie Civil (LMGC) UMR 5508 CNRS – Place Eugène Bataillon, CC048, 34095 Montpellier, France
René Motro
Affiliation:
Université Montpellier 2 – Laboratoire de Mécanique et Génie Civil (LMGC) UMR 5508 CNRS – Place Eugène Bataillon, CC048, 34095 Montpellier, France
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Abstract

Ces travaux montrent la pertinence et l'utilité de la modélisation du cytosquelette des cellules par systèmes mécaniques précontraints. Ces recherches s'inscrivent dans le champ de la biomécanique cellulaire et tissulaire et deux applications sont proposées. On présente tout d'abord la recherche de forme d'une cellule isolée par modèles de tenségrité non réguliers, puis on propose une combinaison entre les modèles granulaires et l'analogie de tenségrité. L'extension prospective aux assemblages multicellulaires avec notion d'autocontrainte partagée, par modèles de grilles de tenségrité est ensuite présentée.

Keywords

Cytoskeletontensegrity structuresgranular mediamodellingtissueCytosquelettestructures de tenségritémilieux granulairesmodélisationtissu
Type
Research Article
Information
Mechanics & Industry , Volume 10 , Issue 3-4: 19e Congrès français de mécanique (CFM 2009) , May 2009 , pp. 285 - 290
Copyright
© AFM, EDP Sciences, 2009

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References

Kumar, S., Maxwell, I.Z., Heisterkamp, A., Polte, T.R., Lele, T., Salanga, M., Mazur, E., Ingber, D.E., Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization and extracellular matrix mechanics, Biophys. J. 90 (2006) 3762–3773 CrossRef
Fabry, B., Maksym, G., Butler, J.P., Glogauer, M., Navajas, D., Fredberg, J.J., Scaling the microrheology of living cells. Phys. Rev. Lett. 87 (2001) 148102
Laurent, V.M., Fodil, R., Cañadas, P., Fereol, S., Louis, B., Planus, E., Isabey, D., Partitioning of cortical and deep cytoskeleton responses from transient magnetic bead twisting. Ann. Biomed. Eng. 31 (2003) 1263–1278
Puig-de-Morales, M., Millet, E.J., Fabry, B., Navajas, D., Wang, N., Butler, J.P., Fredberg, J.J., Cytoskeletal mechanics in adherent human airway smooth muscle cells: probe specificity and scaling of protein-protein dynamics. Am. J. Physiol.: Cell Phys. 287 (2004) 643–654
Harris, A.K., Wild, R., and Stopak, D., Silicone rubber substrata: a new wrinkle in the study of cell locomotion, Science 208 (1980) 177–179 CrossRef
Stamenovic, D., Mijailovic, S., Tolic-Norrelykke, I., Chen, J., Wang, N., Cell pre-stress II. Contribution of microtubules. Am. J. Cell Physiol. 282 (2002) 617–624
Brangwynne, C.P., MacKintosh, F.C., Kumar, S., Geisse, N.A., Talbot, J., Mahadevan, L., Parker, K.K., Ingber, D.E., Weitz, D.A., Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. J. Cell Biol. 173 (2006) 733–741
Stamenovic, D., Coughlin, M.F., The role of prestress and architecture of the cytoskeleton and deformability of cytoskeletal filaments in mechanics of adherent cells: a quantitative analysis. J. Theor. Biol. 201 (1999) 63–74
Cañadas, P., Laurent, V.M., Chabrand, P., Isabey, D., and Wendling-Mansuy, S., Mechanisms Governing the Visco-Elastic Responses of Living Cells Assessed by Foam and Tensegrity Models, Med. Biol. Eng. Comput. 416 (2003) 733–739 CrossRef
Stamenovic, D., Ingber, D.E., Wang, N., and Fredberg, J.J., Microstructural Approach, A to Cytoskeletal Mechanics Based on Tensegrity, J. Theor. Biol. 181 (1996) 125–136 CrossRef
Wendling, S., Oddou, C., and Isabey, D., Stiffening Response of a Cellular Tensegrity Model, J. Theor. Biol. 1963 (1999) 309–325 CrossRef
D.E., Ingber, Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton, J. Cell Sci., 104 (1993) 613–627
Wang, N., Naruse, K., Stamenovic, D., Fredberg, J.J., Mijailovich, S.M., Tolic-Norrelykke, I.M., Polte, T., Mannix, R., Ingber, D.E., Mechanical behavior in living cells consistent with the tensegrity model, Proceedings of the National Academy of Sciences of the USA 98, Vol. 14 (2001) 7765–7770
S. Wendling, P. Cañadas, C. Oddou, and A. Meunier, Interrelations between elastic energy and strain in a tensegrity model; contribution to the analysis on the mechanical response in living cells, Comput. Methods Biomech. Biomed. Eng. 5 (2002) 1–6 CrossRef
Wendling, S., Cañadas, P., and Chabrand, P., Toward a generalized tensegrity model describing the mechanical behaviour of the cytoskeleton structure, Cornput. Methods Biornech. Biorned. Eng. 1 (2003) 1–8
Sultan, C., Stamenovic, D., Ingber, D.E., A computational tensegrity model predicts dynamic rheological behaviors in living cells, Annals Biomed. Eng. 32 (2004) 520–530 CrossRef
Cañadas, P., Laurent, V.M., Oddou, C., Isabey, D., and Wendling, S., Cellular Tensegrity Model, A to Analyse the Structural Viscoelasticity of the Cytoskeleton, J. Theor. Biol. 218 (2002) 155–173 CrossRef
Cañadas, P., Wendling-Mansuy, S., Isabey, D., Frequency response of a viscoelastic trensegrity structure: structural rearrangement contribution to cell dynamics, ASME J. Biomech. Eng. 128 (2006) 487–495 CrossRef
Zhang, L., Maurin, B., Motro, R., Form-finding of non regular tensegrity systems, Journal of Structural Engineering 132 (2006) 1435–1440 CrossRef
Baudriller, H., Maurin, B., Cañadas, P., Montcourrier, P., Parmeggiani, A., Bettache, N., Form-finding of complex tensegrity structures application to cell cytoskeleton modelling Comptes Rendus de l'Académie des Sciences Mécanique 334 (2006) 662–668
Milan, J.L., Wendling-Mansuy, S., Jean, M., Chabrand, P., Divided medium-based model for analyzing the dynamic reorganization of the cytoskeleton during cell deformation, Biomechan. Model Mechanobiol. 6 (2007) 373–390 CrossRef
Maurin, B., Cañadas, P., Baudriller, H., Montcourrier, P., Bettache, N.. Mechanical model of cytoskeleton structuration during cell adhesion and spreading, Journal of Biomechanics 41 (2008) 2036–2041 CrossRef
Keating, TJ., Peloquin, J.G., Rodionov, V.I., Momcilovic, D., Borisy, G.G., Microtubule release from de centrosome, Proceedings of the National Academy of Sciences of the USA 94 (1997) 5078–5083 CrossRef
Sanchez-Sandoval, L., Maurin, B., Kazi Aoual, M.N., Motro, R., Selfstress states identification and localization in modular tensegrity grids, International Journal of Space Structures 22 (2007) 215–224 CrossRef