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Stimuli-Responsive Polymers in Nanotechnology: Deposition and Possible Effect on Drug Release

Published online by Cambridge University Press:  13 December 2008

A. L. Yarin
A. L. Yarin*
Affiliation:
Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL 60607-7022, USA
*
[email protected]
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Abstract

Stimuli-responsive polymers result inon-demand regulation of properties and functioning of variousnanoscale systems. In particular, they allow stimuli-responsivecontrol of flow rates through membranes and nanofluidic deviceswith submicron channel sizes. They also allow regulation of drugrelease from nanoparticles and nanofibers in response totemperature or pH variation in the surrounding medium. In thepresent work two relevant mathematical models are introduced toaddress precipitation-driven deposition of surface layers ofstimuli-responsive polymers and describe a possible effect ofswelling-shrinkage transition of such polymers on drug release.

Keywords

polymer depositionstimuli-responsivepolymersdrug releasefluid and solid mechanicsprobabilitytheory
Type
Research Article
Information
Mathematical Modelling of Natural Phenomena , Volume 3 , Issue 5: Materials Science , 2008 , pp. 1 - 15
Copyright
© EDP Sciences, 2008

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