Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-24T13:01:52.343Z Has data issue: false hasContentIssue false

Approximate Master Equations for Dynamical Processes onGraphs

Published online by Cambridge University Press:  24 April 2014

N. Nagy
Affiliation:
Institute of Mathematics, Eötvös Loránd University Budapest, and Numerical Analysis and Large Networks Research Group, Hungarian Academy of Sciences, Hungary
I.Z. Kiss
Affiliation:
School of Mathematical and Physical Sciences, Department of Mathematics University of Sussex, Falmer, Brighton BN1 9QH, UK
P.L. Simon*
Affiliation:
Institute of Mathematics, Eötvös Loránd University Budapest, and Numerical Analysis and Large Networks Research Group, Hungarian Academy of Sciences, Hungary
*
Corresponding author. E-mail: [email protected]
Get access

Abstract

We extrapolate from the exact master equations of epidemic dynamics on fully connectedgraphs to non-fully connected by keeping the size of the state space N + 1, whereN is thenumber of nodes in the graph. This gives rise to a system of approximate ODEs (ordinarydifferential equations) where the challenge is to compute/approximate analytically thetransmission rates. We show that this is possible for graphs with arbitrary degreedistributions built according to the configuration model. Numerical tests confirm that:(a) the agreement of the approximate ODEs system with simulation is excellent and (b) thatthe approach remains valid for clustered graphs with the analytical calculations of thetransmission rates still pending. The marked reduction in state space gives good results,and where the transmission rates can be analytically approximated, the model provides astrong alternative approximate model that agrees well with simulation. Given that thetransmission rates encompass information both about the dynamics and graph properties, thespecific shape of the curve, defined by the transmission rate versus the number ofinfected nodes, can provide a new and different measure of network structure, and themodel could serve as a link between inferring network structure from prevalence orincidence data.

Type
Research Article
Copyright
© EDP Sciences, 2014

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bátkai, A., Kiss, I.Z., Sikolya, E., Simon, P.L.. Differential equation approximations of stochastic network processes: an operator semigroup approach. Networks and Heterogeneous Media, 7 (2012), 4358. CrossRefGoogle Scholar
B. Bollobás. Random graphs. Cambridge University Press, Cambridge, (2001).
Decreusefond, L., Dhersin, J.-S., Moyal, P., Tran, V. C.. Large graph limit for an SIR process in random network with heterogeneous connectivity. Ann. Appl. Probab., 22 (2012), 541575. CrossRefGoogle Scholar
Eames, K.T.D., Keeling, M.J.. Modeling dynamic and network heterogeneities in the spread of sexually transmitted diseases. PNAS, 99 (2002), 13330-13335. CrossRefGoogle ScholarPubMed
Green, D. M., Kiss, I. Z.. Large-scale properties of clustered networks: Implications for disease dynamics. Journal of Biological Dynamics, 4 (2010), 431-445. CrossRefGoogle ScholarPubMed
House, T., Keeling, M.J.. The impact of contact tracing in clustered populations. PLoS Comput. Biol., 6 (2010), e1000721. CrossRefGoogle Scholar
House, T., Keeling, M. J.. Insights from unifying modern approximations to infections on networks. J. Roy. Soc. Interface, 8 (2011), 67-73. CrossRefGoogle ScholarPubMed
Keeling, M.J.. The effects of local spatial structure on epidemiological invasions. Proc. R. Soc. Lond. B, 266 (1999), 859-867. CrossRefGoogle ScholarPubMed
Keeling, M.J., Eames, K.T.D.. Networks and epidemic models. J. Roy. Soc. Interface, 2 (2005), 295-307. CrossRefGoogle ScholarPubMed
Lindquist, J., Ma, J., van den Driessche, P., Willeboordse, F.H.. Effective degree network disease models. J. Math. Biol., 62 (2011), 143-164. CrossRefGoogle ScholarPubMed
Marceau, V., Noël, P.-A., Hébert-Dufresne, L., Allard, A., Dubé, L. J.. Adaptive networks: coevolution of disease and topology. Phys. Rev. E., 82 (2010), 036116. CrossRefGoogle ScholarPubMed
Miller, J. C., Slim, A. C., Volz, E. M.. Edge-based compartmental modelling for infectious disease spread. J. R. Soc. Interface, 9 (70) (2012), 890906. CrossRefGoogle ScholarPubMed
Roy, M., Pascual, M.. On representing network heterogeneities in the incidence rate of simple epidemic models. Ecol. Complexity, 3 (2006), 80-90. CrossRefGoogle Scholar
Simon, P. L., Kiss, I. Z.. From exact stochastic to mean-field ODE models: a new approach to prove convergence results. IMA J. Appl. Math., 78 (5) (2013), 945-964. CrossRefGoogle Scholar
Simon, P.L., Taylor, M., Kiss, I.Z.. Exact epidemic models on graphs using graph-automorphism driven lumping. J. Math. Biol., 62 (2012), 479-508. CrossRefGoogle ScholarPubMed
Taylor, M., Simon, P. L., Green, D. M., House, T., Kiss, I. Z.. From Markovian to pairwise epidemic models and the performance of moment closure approximations. J. Math. Biol., 64 (2012), 1021-1042. CrossRefGoogle ScholarPubMed