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The Effect of Narcotics on the Endogenous Respiration and Succinate Oxidation in Oyster Muscle

Published online by Cambridge University Press:  11 May 2009

George Frederick Humphrey
George Frederick Humphrey
Affiliation:
Department of Biochemistry, University of Sydney, Australia
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Extract

The action of the following compounds on homogenates of the adductor muscles of Saxostrea commercialis was studied: urethane, phenyl urethane, chloral hydrate, salicylic acid, morphine, caffeine, barbitone, benzoic acid, salicylamide and benzamide.

It was found that, except for 0·05 M urethane, the endogenous oxygen consumption was reduced by all these compounds when present in concentrations ranging from o·001 to 0·05M. The oxidation of succinic acid was partially inhibited by these substances.

These findings are discussed in relation to similar studies on other tissues.

Type
Research Article
Information
Journal of the Marine Biological Association of the United Kingdom , Volume 27 , Issue 2 , April 1948 , pp. 504 - 512
Copyright
Copyright © Marine Biological Association of the United Kingdom 1948

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