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Neurobehavioral deficits associated with chronic fatigue syndrome in veterans with Gulf War unexplained illnesses

Published online by Cambridge University Press:  11 January 2002

LAURENCE M. BINDER ,
DANIEL STORZBACH ,
KEITH A. CAMPBELL ,
DIANE S. ROHLMAN  and
W. KENT ANGER
LAURENCE M. BINDER
Affiliation:
Oregon Health Sciences University, Portland Oregon
DANIEL STORZBACH
Affiliation:
Oregon Health Sciences University, Portland Oregon Portland Veterans Affairs Medical Center
KEITH A. CAMPBELL
Affiliation:
Oregon Health Sciences University, Portland Oregon Portland Veterans Affairs Medical Center
DIANE S. ROHLMAN
Affiliation:
Oregon Health Sciences University, Portland Oregon
W. KENT ANGER
Affiliation:
Oregon Health Sciences University, Portland Oregon
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Abstract

Gulf War unexplained illnesses (GWUI) are a heterogeneous collection of symptoms of unknown origin known to be more common among veterans of the Gulf War than among nonveterans. In the present study we focused on one of these unexplained illnesses. We tested the hypothesis that in a sample of Persian Gulf War veterans chronic fatigue syndrome (CFS) was associated with cognitive deficits on computerized cognitive testing after controlling for the effects of premorbid cognitive differences. We obtained Armed Forces Qualification Test (AFQT) data acquired around the date of induction into the military on 94 veterans of the Gulf War, 32 with CFS and 62 healthy controls. Controls performed better than participants diagnosed with CFS on the AFQT. Cognitive deficits were associated with CFS on 3 of 8 variables after the effect of premorbid AFQT scores was removed with ANCOVA. (JINS, 2001, 7, 835–839.)

Keywords

Chronic fatigue syndromeCognitive functionGulf War unexplained illnesses
Type
Research Article
Information
Journal of the International Neuropsychological Society , Volume 7 , Issue 7 , November 2001 , pp. 835 - 839
Copyright
© 2001 The International Neuropsychological Society

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