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Autobiographical memory in multiple sclerosis

Published online by Cambridge University Press:  01 May 1997

ROBERT H. PAUL
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center, Center for Alcohol and Drug Related Studies, Oklahoma City, OK 73190
CARLOS R. BLANCO
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center, Center for Alcohol and Drug Related Studies, Oklahoma City, OK 73190
KAREN A. HAMES
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center, Center for Alcohol and Drug Related Studies, Oklahoma City, OK 73190
WILLIAM W. BEATTY
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center, Center for Alcohol and Drug Related Studies, Oklahoma City, OK 73190

Abstract

Studies have consistently found that patients with multiple sclerosis (MS) are impaired on tests of anterograde memory, but the status of remote memory in MS remains unclear. To better understand remote memory in MS we administered the Autobiographical Memory Interview (AMI) to 44 MS patients and 19 normal controls matched for age, education, and gender. Additionally, a shortened version of the Famous Faces Test, a test of recall of past U.S. presidents, and a 14-word learning list were administered. Patients performed significantly lower than controls on the learning list and Famous Faces Test, but not on recall of past presidents. On the AMI, patients were significantly impaired on recall of semantic but not of episodic memories. These results indicate that MS patients exhibit retrograde amnesia that cannot be attributed to anterograde memory deficits or lack of exposure to task-relevant information. (JINS, 1997, 3, 246–251.)

Type
Research Article
Copyright
© 1997 The International Neuropsychological Society

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