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Neural substrates of object identification: Functional magnetic resonance imaging evidence that category and visual attribute contribute to semantic knowledge

Published online by Cambridge University Press:  01 March 2009

CHRISTINA E. WIERENGA ,
WILLIAM M. PERLSTEIN ,
MICHELLE BENJAMIN ,
CHRISTIANA M. LEONARD ,
LESLIE GONZALEZ ROTHI ,
TIM CONWAY ,
M. ALLISON CATO ,
KAUNDINYA GOPINATH ,
RICHARD BRIGGS  and
BRUCE CROSSON
CHRISTINA E. WIERENGA*
Affiliation:
Department of Veterans Affairs Rehabilitation Research and Development, Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida McKnight Brain Institute, University of Florida, Gainesville, Florida
WILLIAM M. PERLSTEIN
Affiliation:
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida McKnight Brain Institute, University of Florida, Gainesville, Florida
MICHELLE BENJAMIN
Affiliation:
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida McKnight Brain Institute, University of Florida, Gainesville, Florida
CHRISTIANA M. LEONARD
Affiliation:
McKnight Brain Institute, University of Florida, Gainesville, Florida Department of Neuroscience, University of Florida, Gainesville, Florida
LESLIE GONZALEZ ROTHI
Affiliation:
Department of Veterans Affairs Rehabilitation Research and Development, Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida McKnight Brain Institute, University of Florida, Gainesville, Florida Department of Neurology, University of Florida, Gainesville, Florida
TIM CONWAY
Affiliation:
Department of Veterans Affairs Rehabilitation Research and Development, Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida McKnight Brain Institute, University of Florida, Gainesville, Florida
M. ALLISON CATO
Affiliation:
Division of Neurology, Nemours Children’s Clinic, Jacksonville, Florida
KAUNDINYA GOPINATH
Affiliation:
Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida Department of Radiology, University of Texas Southwestern Medical School, Dallas, Texas
RICHARD BRIGGS
Affiliation:
Department of Radiology, University of Texas Southwestern Medical School, Dallas, Texas Department of Radiology, University of Florida, Gainesville, Florida
BRUCE CROSSON
Affiliation:
Department of Veterans Affairs Rehabilitation Research and Development, Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida McKnight Brain Institute, University of Florida, Gainesville, Florida
*
*Correspondence and reprint requests to: Christina E. Wierenga, UCSD Department of Psychiatry, VA San Diego Healthcare System, Psychology Service (151B), 3350 La Jolla Village Drive, San Diego, California 92161. E-mail: [email protected]
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Abstract

Recent findings suggest that neural representations of semantic knowledge contain information about category, modality, and attributes. Although an object’s category is defined according to shared attributes that uniquely distinguish it from other category members, a clear dissociation between visual attribute and category representation has not yet been reported. We investigated the contribution of category (living and nonliving) and visual attribute (global form and local details) to semantic representation in the fusiform gyrus. During functional magnetic resonance imaging (fMRI), 40 adults named pictures of animals, tools, and vehicles. In a preliminary study, identification of objects in these categories was differentially dependent on global versus local visual feature processing. fMRI findings indicate that activation in the lateral and medial regions of the fusiform gyrus distinguished stimuli according to category, that is, living versus nonliving, respectively. In contrast, visual attributes of global form (animals) were associated with higher activity in the right fusiform gyrus, while local details (tools) were associated with higher activity in the left fusiform gyrus. When both global and local attributes were relevant to processing (vehicles), cortex in both left and right medial fusiform gyri was more active than for other categories. Taken together, results support distinctions in the role of visual attributes and category in semantic representation. (JINS, 2009, 15, 169–181.)

Keywords

Semantic organizationFunctional MRIRecognitionTemporal lobeLanguageVisual perception
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 15 , Issue 2 , March 2009 , pp. 169 - 181
Copyright
Copyright © INS 2009

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