Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-26T05:12:12.077Z Has data issue: false hasContentIssue false
  • English
  • Français

Alternate but Do Not Swim: A Test for Executive Motor Dysfunction in Parkinson Disease

Published online by Cambridge University Press:  10 June 2011

Adam D. Falchook ,
Danilo Decio ,
John B. Williamson ,
Michael S. Okun ,
Irene A. Malaty ,
Ramon L. Rodriguez  and
Kenneth M. Heilman
Adam D. Falchook*
Affiliation:
Department of Neurology, University of Florida, Gainesville, Florida Department of Neurology, Malcom Randall Veterans Affairs Medical Center, Gainesville, Florida
Danilo Decio
Affiliation:
College of Medicine, University of Florida, Gainesville, Florida
John B. Williamson
Affiliation:
Department of Neurology, University of Florida, Gainesville, Florida Department of Neurology, Malcom Randall Veterans Affairs Medical Center, Gainesville, Florida
Michael S. Okun
Affiliation:
Department of Neurology, University of Florida, Gainesville, Florida Movement Disorders Center, University of Florida, Gainesville, Florida
Irene A. Malaty
Affiliation:
Department of Neurology, University of Florida, Gainesville, Florida Department of Neurology, Malcom Randall Veterans Affairs Medical Center, Gainesville, Florida Movement Disorders Center, University of Florida, Gainesville, Florida
Ramon L. Rodriguez
Affiliation:
Department of Neurology, University of Florida, Gainesville, Florida Movement Disorders Center, University of Florida, Gainesville, Florida
Kenneth M. Heilman
Affiliation:
Department of Neurology, University of Florida, Gainesville, Florida Department of Neurology, Malcom Randall Veterans Affairs Medical Center, Gainesville, Florida Movement Disorders Center, University of Florida, Gainesville, Florida Center for Neuropsychological Studies, University of Florida, Gainesville, Florida
*
Correspondence and reprint requests to: Adam Falchook, Department of Neurology, McKnight Brain Institute at UF, 100 South Newell Drive, Room L3-100, PO Box 100236, Gainesville, FL 32610-0236. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

The objective of this study is to learn if participants with Parkinson disease (PD), when compared to normal controls, are impaired in making simultaneous but independent right and left hand movements. Participants were tested with Luria's Alternating Hand Postures (AHP) test and modified AHP tests. Twelve PD participants without dementia and twelve matched controls were assessed for their ability to perform the parallel AHP test (both hands remaining in the same coronal plane) and with modifications of this test into swimming (alternative arm extension with finger extension and arm flexion with finger flexion) and reverse swimming (alternative arm extension—finger flexion and arm flexion—finger extension) movements. The participants with PD were significantly impaired when performing the parallel and the reverse swimming movements AHP tests, but not impaired on the swimming movements AHP test. Swimming movements may be phylogenetically and ontogenetically more primitive and not as heavily dependent on frontal-basal ganglia networks; thus performance of swimming movements during the parallel AHP test may decrease this test's sensitivity. (JINS, 2011, 17, 702–708)

Keywords

Parkinson diseaseBimanual coordinationAntiphase movementsPremotorBasal gangliaCentral pattern generators
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 17 , Issue 4 , 21 June 2011 , pp. 702 - 708
Copyright
Copyright © The International Neuropsychological Society 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Benecke, R., Rothwell, J.C., Dick, J.P., Day, B.L., Marsden, C.D. (1986). Performance of simultaneous movements in patients with Parkinson's disease. Brain, 109, 739–757.CrossRefGoogle ScholarPubMed
Benecke, R., Rothwell, J.C., Dick, J.P., Day, B.L., Marsden, C.D. (1987). Simple and complex movements off and on treatment in patients with Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry, 50, 296–303.CrossRefGoogle ScholarPubMed
Brinkman, C. (1984). Supplementary motor area of the monkey's cerebral cortex: Short- and long-term deficits after unilateral ablation and the effects of subsequent callosal section. Journal of Neuroscience, 4, 918–929.CrossRefGoogle Scholar
Colwin, C. (2002). History of the swimming strokes. In C. McEntire & S. Hawkins (Eds.), Breakthrough swimming: Stroke mechanics, training methods, racing techniques. Champaign, IL: Human Kinetics.Google Scholar
Crucian, G.P., Heilman, K., Junco, E., Maraist, M., Owens, W.E., Foote, K.D., Okun, M.S. (2007). The crossed response inhibition task in Parkinson's disease: Disinhibition hyperkinesia. Neurocase, 13, 158–164.CrossRefGoogle ScholarPubMed
Edmunds, L. (2006). Oedipus (Gods and heroes of the ancient world) (pp. 19). New York, NY and Abingdon, Oxon: Routledge.Google Scholar
Gelb, D.J., Oliver, E., Gilman, S. (1999). Diagnostic criteria for Parkinson's disease. Archives of Neurology, 56, 33–39.CrossRefGoogle Scholar
Grefkes, C., Eickhoff, S.B., Nowak, D.A., Dafotakis, M., Fink, G.R. (2008). Dynamic intra- and interhemispheric interactions during unilateral and bilateral hand movements assessed with fMRI and DCM. Neuroimage, 41, 1382–1394.CrossRefGoogle ScholarPubMed
Grillner, S., Hellgren, J., Ménard, A., Saitoh, K., Wikström, M.A. (2005). Mechanisms for selection of basic motor programs--roles for the striatum and pallidum. Trends in Neurosciences, 28(7), 364–370.CrossRefGoogle ScholarPubMed
Hughlings-Jackson, J. (1887). Remarks on evolution and dissolution of the nervous system. Journal of Mental Science, 23, 25–48.CrossRefGoogle Scholar
Immisch, I., Waldvogel, D., van Gelderen, P., Hallett, M. (2001). The role of the medial wall and its anatomical variations for bimanual antiphase and in-phase movements. Neuroimage, 14(3), 674–684.CrossRefGoogle Scholar
Jankovic, J. (2008). Parkinson's disease: Clinical features and diagnosis. Journal of Neurology, Neurosurgery, and Psychiatry, 79, 368–376.CrossRefGoogle ScholarPubMed
Johnson, K.A., Cunnington, R., Bradshaw, J.L., Phillips, J.G., Iansek, R., Rogers, M.A. (1998). Bimanual co-ordination in Parkinson's disease. Brain, 121(4), 743–753.CrossRefGoogle ScholarPubMed
Kazennikov, O., Hyland, B., Wicki, U., Perrig, S., Rouiller, E.M., Wiesendanger, M. (1998). Effects of lesions in the mesial frontal cortex on bimanual co-ordination in monkeys. Neuroscience, 85, 703–716.CrossRefGoogle ScholarPubMed
Kermadi, I., Liu, Y., Tempini, A., Rouiller, E.M. (1997). Effects of reversible inactivation of the supplementary motor area (SMA) on unimanual grasp and bimanual pull and grasp performance in monkeys. Somatosensory Motor Research, 14, 268–280.CrossRefGoogle ScholarPubMed
Kornhuber, H.H., Deecke, L. (1965). Changes in the brain potential in voluntary movements and passive movements in man: Readiness potential and reafferent potentials. Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere, 284, 1–17.CrossRefGoogle ScholarPubMed
Laplane, D., Talairach, J., Meininger, V., Bancaud, J., Orgogozo, J.M. (1977). Clinical consequences of corticectomies involving the supplementary motor area in man. Journal of the Neurological Sciences, 34, 301–314.CrossRefGoogle ScholarPubMed
Levy, R., Lang, A.E., Hutchison, W.D., Lozano, A.M., Dostrovsky, J.O. (2002). Simultaneous repetitive movements following pallidotomy or subthalamic deep brain stimulation in patients with Parkinson's disease. Experimental Brain Research, 147, 322–331.Google ScholarPubMed
Luria, A.R. (1966). Investigation of motor functions. Higher cortical functions in man. Translated by Basil Haigh. New York, NY: Basic Books.Google Scholar
Marder, E., Bucher, D. (2001). Central pattern generators and the control of rhythmic movements. Current Biology, 11(23), R986–R996.CrossRefGoogle ScholarPubMed
Nasreddine, Z.S., Phillips, N.A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment. Journal of the American Geriatric Society, 53, 695–699.CrossRefGoogle Scholar
Ozeretskii, N.I. (1930). Techniquie of investigating motor function. In M. Gurevich & N. Ozeretskii (Eds.), Psychomotor functions. Moscow: Medzig.Google Scholar
Schwab, R.S., Chafetz, M.E., Walker, S. (1954). Control of two simultaneous voluntary motor acts in normals and in parkinsonism. AMA Archives of Neurology and Psychiatry, 72, 591–598.CrossRefGoogle ScholarPubMed
Shibasaki, H., Hallett, M. (2006). What is the Bereitschaftspotential? Clinical Neurophysiology, 117, 2341–2356.CrossRefGoogle ScholarPubMed
Swanson, L.W. (2005). Anatomy of the soul as reflected in the cerebral hemispheres: Neural circuits underlying voluntary control of basic motivated behaviors. Journal of Comparative Neurology, 493(1), 122–131.CrossRefGoogle ScholarPubMed
Whelan, P.J. (1996). Control of locomotion in the decerebrate cat. Progress in Neurobiology, 49(5), 481–515.CrossRefGoogle ScholarPubMed
Wu, T., Hallett, M. (2008). Neural correlates of dual task performance in patients with Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry, 79, 760–766.CrossRefGoogle ScholarPubMed