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A novel approach to assess mean lethal radiation dose with water proton spin lattice relaxation times

Published online by Cambridge University Press:  12 November 2010

Syed F. Akber  and
Than S. Kehwar
Syed F. Akber
Affiliation:
Department of Radiation Oncology, Case Western Reserve University, Cleveland, Ohio, USA
Than S. Kehwar*
Affiliation:
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, UPMC Cancer Centers, Pennsylvania, USA
*
Correspondence to: Than S. Kehwar, Department of Radiation Oncology, University of Pittsburgh Cancer Institute, UPMC St. Margaret Hospital, Pittsburgh, PA 15215. E-mail: [email protected]
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Abstract

The assessment of mean lethal radiation dose (D0) in human organs, using multi-target and linear quadratic models, with water proton nuclear magnetic resonance spin lattice relaxation time yields a correlation coefficient of 0.90 and 0.82, respectively. Results of this study reveal that as the spin lattice relaxation time increases, the D0 decreases.

Keywords

Mean lethal radiation dosesproton spin lattice relaxation timesmulti-target modellinear quadratic model
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 10 , Issue 2 , June 2011 , pp. 117 - 119
Copyright
Copyright © Cambridge University Press 2010

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References

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