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Dosimetric comparison of TMR10 and convolution dose calculation algorithms in GammaPlan treatment planning system

Published online by Cambridge University Press:  04 June 2019

Ethan Kendall ,
Ozer Algan ,
Yong Chen  and
Salahuddin Ahmad
Ethan Kendall*
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
Ozer Algan
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
Yong Chen
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
Salahuddin Ahmad
Affiliation:
Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, Oklahoma City, OK, USA
*
Author for correspondence: Ethan Kendall, Department of Radiation Oncology, Peggy & Charles Stephenson Cancer Center, University of Oklahoma HSC, 800 NE 10th St, Oklahoma City, OK 73104, USA. Tel: (405) 271-1112. E-mail: [email protected]
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Abstract

Aims:

In this article, our goal is to compare the TMR10 and convolution dose calculation algorithm in GammaPlan used in stereotactic radiosurgery (SRS) treatments with Gamma Knife and to assess if the algorithms produce clinically significant differences.

Materials and methods:

Treatment plans were analysed from ten patients who have undergone Gamma Knife SRS treatments. Patient plans were retrospectively recalculated using Lesksell GammaPlan 10 treatment software utilising the TMR10 and convolution dose calculation algorithms in order to create a paired dataset for comparison. Evaluation was based on the dose volume histogram (parameters of minimum, mean, maximum and integral doses.

Results:

The ratios of average integral doses calculated by the convolution dose calculation algorithm to the average integral doses calculated by the TMR10 algorithm are 0·997 for the target (p=0·028), 1·048 (p=0·48) for the skull and 1·005 (p=0·68) for the brainstem.

Conclusions:

Although doses calculated with the convolution algorithm resulted in slightly higher mean integral doses for the brainstem and skull critical structures when compared to that of TMR10 doses, these results were not statistically or clinically significant. Thus we continue to use the TMR10 algorithm at our clinic.

Keywords

dosimetric comparisonGamma knifeheterogeneity correctionstereotactic radiosurgery
Type
Technical Note
Information
Journal of Radiotherapy in Practice , Volume 19 , Issue 1 , March 2020 , pp. 93 - 97
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Copyright
© Cambridge University Press 2019 

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