Hostname: page-component-cc8bf7c57-fxdwj Total loading time: 0 Render date: 2024-12-11T22:54:22.327Z Has data issue: false hasContentIssue false
  • English
  • Français

Sympathetic Blockade in the Treatment of Anxiety States

Published online by Cambridge University Press:  08 February 2018

S. Smith
S. Smith*
Affiliation:
Barrow Hospital, Barrow Gurney, near Bristol
Get access Rights & Permissions [Opens in a new window]

Extract

Paton and Zaimis (1949) showed that the members of a series of compounds composed of two tri-methyl ammonium groups linked by a polymethylene chain had various actions, such as producing neuro-muscular blocking, inhibition of cholinesterase, a muscarine-like action and a blocking of impulses at the autonomic ganglia. It has been found that hexamethonium is the most active of the above compounds in these respects, and the autonomic ganglionic blocking properties have clinical applications. Hexamethonium is usually used clinically as a dibromide.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 98 , Issue 410 , January 1952 , pp. 161 - 166
Copyright
Copyright © Royal College of Psychiatrists, 1952 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

(1) Paton, W. D. M., and Zaimis, E. J., Brit. J. Pharmacol., 1949, 4, 381.Google Scholar
(2) Campbell, A., and Robertson, E., Brit, Med. J., 1950, ii, 804.Google Scholar
(3) Kay, A. W., and Smith, A. N., ibid., 1950, i, 460.Google Scholar
(4) Cannon, W. B., Bodily Changes in Pain, Hunger, Fear and Rage, 1935. New York.Google Scholar
(5) Wolf, S., and Wolff, H. G., Human Gastric Function, 1943, New York and London : Oxford University Press.Google Scholar
(6) James, W., Principles of Psychology, 1905. London.Google Scholar
(7) Lange, C., Über Gemüthsbewegungen, 1887. Leipzig.Google Scholar
(8) Wittkower, E., J. Ment. Sci., 1935, 81, 533.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.