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Imipramine in Chronic Depression

Published online by Cambridge University Press:  08 February 2018

P. A. Barker ,
G. W. Ashcroft  and
J. K. Binns
P. A. Barker
Affiliation:
The Royal Edinburgh Hospital for Mental and Nervous Disorders (Craig House Section)
G. W. Ashcroft
Affiliation:
The Royal Edinburgh Hospital for Mental and Nervous Disorders (Craig House Section)
J. K. Binns
Affiliation:
The Royal Edinburgh Hospital for Mental and Nervous Disorders (Craig House Section)
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Extract

Imipramine hydrochloride (N-(γ-dimethylaminopropyl)-iminodibenzyl hydrochloride, “Tofranil”) has been shown by many investigators to be of value in the treatment of depressive states. The reports of Kuhn (1957, 1958) and of Kielholz and Battegay (1958) have been followed by confirmatory papers from other authors. A number of contributors to the McGill University Symposium on Depression and Allied States (1959) commented favourably on the value of imipramine in depression; Hoff, however, while agreeing that the drug is useful in acute depressions stated that he found it ineffective in chronic depression.

Type
Original Articles
Information
Journal of Mental Science , Volume 106 , Issue 445 , October 1960 , pp. 1447 - 1451
Copyright
Copyright © Royal College of Psychiatrists, 1960 

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References

Ball, J. R. B., and Kiloh, L. G., Brit. med. J., 1959, ii, 1052.Google Scholar
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