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The Blood Cholesterol in Epilepsy in Relation to Treatment by Dehydration and Ketogenesis

Published online by Cambridge University Press:  19 February 2018

J. H. McLean
J. H. McLean*
Affiliation:
Alexandra Institution for Feeble-minded, Maitland, Cape of Good Hope, South Africa
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Extract

Cholesterol metabolism in epilepsy has been investigated by a number of observers during recent years, but the results have been contradictory and confusing, as the following summary shows: 1920, De Crinis (1): Cholesterol increased before seizures. 1923, Pezzali (2): Cholesterol decreased before seizures; low average levels in epileptics. 1927, Robinson, Brain and Kay (3): Cholesterol decreased before seizures. 1927, Osnato and Killian (4): Results negative. 1929, Goodall (5): Results negative. 1929, Fox Gosden and Brain (6): Cholesterol decreased before seizures; general low values in epileptics and increased variability in individual patients. 1930, Duncan (7): That there is no definite evidence to show that the occurrence of an epileptic fit is associated with a fall in the level of cholesterol in the blood.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 80 , Issue 328 , January 1934 , pp. 82 - 86
Copyright
Copyright © Royal College of Psychiatrists, 1934

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References

1Crinis, De, quoted by Lennox, and Cobb, , Medicine, vii, 1928.Google Scholar
2Pezzali, , ibid., vii, 1928.Google Scholar
3Robinson, , Brain, and Kay, , Lancet, 1927, ii, p. 325.10.1016/S0140-6736(01)30867-XGoogle Scholar
4Osnato, and Killian, , Brain, 1927, i, p. 581.Google Scholar
5Goodall, , Lancet, 1929, i, p. 384.10.1016/S0140-6736(01)37548-7Google Scholar
6Gosden, Fox and Brain, , ibid., July 6th, 1929.Google Scholar
7Duncan, , Journ. Ment. Sci., April, 1930.Google Scholar
8Shaw, and Sharpe, , ibid., January, 1931.Google Scholar
9Sackett, , Journ. Biol. Chem., 1925, lxiv, p. 203.10.1016/S0021-9258(18)84961-4Google Scholar
10Fay, Temple, Amer. Journ. Psychiat., March, 1929.Google Scholar
11Ross, Gamble and Tisdale, , Journ. Biol. Chem., lvii, October, 1923.Google Scholar
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