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Withdrawal of a Conical Pin From a Pool of Liquid

Published online by Cambridge University Press:  05 May 2011

A.-B. Wang ,
Y.-S. Chen ,
Y.-J. Wu ,
J.-Y. Sung  and
A. L. Yarin
A.-B. Wang*
Affiliation:
Institute of Applied Mechanics, National Taiwan University, Taipei, Taiwan 10617, R.O.C.
Y.-S. Chen*
Affiliation:
Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan 10617, R.O.C.
Y.-J. Wu*
Affiliation:
Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan 10617, R.O.C.
J.-Y. Sung*
Affiliation:
Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan 10617, R.O.C.
A. L. Yarin*
Affiliation:
Faculty of Mechanical Engineering, Technion —Israel Institute of Technology, Haifa, 32000Israel
*
*Professor
**undergraduate student
**undergraduate student
**undergraduate student
*Professor
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Abstract

The development of biochips leads to a straightforward, fast and cost effective method to obtain valuable genetic information. A key element of the emerging biochip technology is a microarray system, which fabricates high-density samples on solid materials of a microscopic area. In particular, dots of test liquid are printed on solids by a system of pins constituting a microarray. At present, however, the technique cannot make dots of arbitrary equivalent and controllable size. On the other hand, printing pins in microarrays represent themselves as a particular example of dip coating. In the experiments of the present work, a model of tapered stainless steel needle was withdrawn from different glycerine-water mixtures. Thicknesses and volumes of the withdrawn liquid films were measured as a function of the needle geometry, immersion depth, withdrawal rate, and physical parameters of the liquid. The experimental data are analyzed as a function of the capillary number Ca based on the withdrawal speed and compared to the predictions of the modified Landau-Levich-Deryagin (LLD) theory. The results show that for Ca < 10-2 the thickness and the volume of the liquid follow the Ca2/3-scaling, while for Ca >10-2 — the Ca½-scaling, as it is expected from the LLD theory. Flow visualization is utilized to resolve the detail flow structure. The results put the key element of the pin-printing technology exploited in microarrays into a familiar hydrodynamic context of dip coating. This allows one to expect that under appropriate operational conditions, high-precision sampling could be attainable.

Keywords

Conical pinWithdrawn liquidFlow visualization.
Type
Articles
Information
Journal of Mechanics , Volume 20 , Issue 3 , September 2004 , pp. 219 - 232
Copyright
Copyright © The Society of Theoretical and Applied Mechanics, R.O.C. 2004

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