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An Axial Velocity Profile Method to Derive the Aortic Pulse-Wave Velocity in Diabaetic Patients

Published online by Cambridge University Press:  31 August 2011

C.-Y. Wen
Affiliation:
Department of Aeronautics and Astronautics, National Cheng Kung University, Tainan, Taiwan 70101, R.O.C.
A.-S. Yang*
Affiliation:
Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan 10608, R.O.C.
T.-R. Kuo
Affiliation:
Department of Aeronautics and Astronautics, National Cheng Kung University, Tainan, Taiwan 70101, R.O.C.
L.-Y. Tseng
Affiliation:
Institute of Mechatronic Engineering, National Taipei University of Technology, Taipei, Taiwan 10608, R.O.C.
J.-W. Chai
Affiliation:
Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan 40705, R.O.C.
*
**Professor, corresponding author
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Abstract

The aortic pulse wave velocity (PWV) is a useful clinical index to assess the aortic compliance and cardiovascular risk in a noninvasive manner. In this research, our previously developed axial velocity profile method (Yu et al., [11]) was modified to be more user-friendly and applied to the study of PWV of diabetic patients for the first time, using phase-contrast magnetic resonance imaging (PC-MRI) technique to analyze the spatial and temporal profiles of the axial velocity along the descending aorta for measurement of the aortic PWV. The PWV results from healthy volunteers and diabetic patients were studied and compared. It is shown that the PWV of diabetic patients is much higher than that of health volunteers, the aortic compliance of diabetic patients is substantially worse than that of health volunteers. These results are in good agreement with early studies using different measurement techniques of PWV. The axial velocity profile method is again validated and proven to be a useful tool of long-term prognosis for patients with diabetes mellitus or hypertension.

Type
Articles
Copyright
Copyright © The Society of Theoretical and Applied Mechanics, R.O.C. 2011

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References

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