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High-resolution solid state NMR experiments for the characterization of calcium phosphate biomaterials and biominerals

Published online by Cambridge University Press:  07 September 2011

Frédérique Pourpoint ,
Cristina Coelho Diogo ,
Christel Gervais ,
Christian Bonhomme ,
Franck Fayon ,
Sara Laurencin Dalicieux ,
Isabelle Gennero ,
Jean-Pierre Salles ,
Andrew P. Howes  and
Ray Dupree
...Show all authors
Frédérique Pourpoint
Affiliation:
Laboratoire Chimie de la Matière Condensée de Paris, UMR CNRS 7574, UPMC Université Paris 06, Collège de France, 75231 Paris cedex 05, France
Cristina Coelho Diogo
Affiliation:
Laboratoire Chimie de la Matière Condensée de Paris, UMR CNRS 7574, UPMC Université Paris 06, Collège de France, 75231 Paris cedex 05, France
Christel Gervais
Affiliation:
Laboratoire Chimie de la Matière Condensée de Paris, UMR CNRS 7574, UPMC Université Paris 06, Collège de France, 75231 Paris cedex 05, France
Christian Bonhomme
Affiliation:
Laboratoire Chimie de la Matière Condensée de Paris, UMR CNRS 7574, UPMC Université Paris 06, Collège de France, 75231 Paris cedex 05, France
Franck Fayon
Affiliation:
CEMHTI, CNRS UPR 3079, 45071 Orléans cedex 2, France
Sara Laurencin Dalicieux
Affiliation:
INSERM Unité 563 (Centre de Physiopathologie de Toulouse Purpan), Université Paul-Sabatier, Hôpital Purpan, CHU de Toulouse, 31059 Toulouse cedex 9, France
Isabelle Gennero
Affiliation:
INSERM Unité 563 (Centre de Physiopathologie de Toulouse Purpan), Université Paul-Sabatier, Hôpital Purpan, CHU de Toulouse, 31059 Toulouse cedex 9, France
Jean-Pierre Salles
Affiliation:
INSERM Unité 563 (Centre de Physiopathologie de Toulouse Purpan), Université Paul-Sabatier, Hôpital Purpan, CHU de Toulouse, 31059 Toulouse cedex 9, France
Andrew P. Howes
Affiliation:
Department of Physics, University of Warwick, CV4 7AL Coventry, UK
Ray Dupree
Affiliation:
Department of Physics, University of Warwick, CV4 7AL Coventry, UK
John V. Hanna
Affiliation:
Department of Physics, University of Warwick, CV4 7AL Coventry, UK
Mark E. Smith
Affiliation:
Department of Physics, University of Warwick, CV4 7AL Coventry, UK
Francesco Mauri
Affiliation:
Laboratoire de Minéralogie Cristallographie UMR CNRS 7590, UPMC Université Paris 06, France
Gilles Guerrero
Affiliation:
Institut Charles Gerhardt de Montpellier, UMR 5253, CNRS UM2 UM1 ENSCM, CC 1701 Université de Montpellier 2, 34095 Montpellier cedex 5, France
P. Hubert Mutin
Affiliation:
Institut Charles Gerhardt de Montpellier, UMR 5253, CNRS UM2 UM1 ENSCM, CC 1701 Université de Montpellier 2, 34095 Montpellier cedex 5, France
Danielle Laurencin*
Affiliation:
Institut Charles Gerhardt de Montpellier, UMR 5253, CNRS UM2 UM1 ENSCM, CC 1701 Université de Montpellier 2, 34095 Montpellier cedex 5, France
*
a)Address all correspondence to this author. e-mail: [email protected]
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Abstract

Calcium phosphates form a vast family of biominerals, which have attracted much attention in fields like biology, medicine, and materials science, to name a few. Solid state Nuclear Magnetic Resonance (NMR) is one of the few techniques capable of providing information about their structure at the atomic level. Here, examples of recent advances of solid state NMR techniques are given to demonstrate their suitability to characterize in detail synthetic and biological calcium phosphates. Examples of high-resolution 31P, 1H (and 17O), solid state NMR experiments of a 17O-enriched monocalcium phosphate monohydrate-monetite mixture and of a mouse tooth are presented. In both cases, the advantage of performing fast Magic Angle Spinning NMR experiments at high magnetic fields is emphasized, notably because it allows very small volumes of sample to be analyzed.

Keywords

BiomaterialNuclear magnetic resonanceBone
Type
Invited Feature Paper
Information
Journal of Materials Research , Volume 26 , Issue 18 , 28 September 2011 , pp. 2355 - 2368
Copyright
Copyright © Materials Research Society 2011

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