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Design and mechanical properties simulation of fish scale-like intracranial thrombectomy stent

Published online by Cambridge University Press:  08 July 2020

Feng Zhao
Affiliation:
Traditional Chinese Medicine Hospital of China Three Gorges University, Yichang Hospital of Traditional Chinese Medicine, Yichang443003, China
Ya Yang
Affiliation:
Department of Geriatrics, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an 223003, China
Yongjuan Zhao*
Affiliation:
Department of Geriatrics, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an 223003, China
Yanchun Wei
Affiliation:
Faculty of Mechanical and Material Engineering, Huaiyin Institute of Technology, Huai'an 223003, China
Li Quan
Affiliation:
Faculty of Mechanical and Material Engineering, Huaiyin Institute of Technology, Huai'an 223003, China
Changjiang Pan*
Affiliation:
Faculty of Mechanical and Material Engineering, Huaiyin Institute of Technology, Huai'an 223003, China
*
a)Address all correspondence to these authors. e-mail: [email protected]
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Abstract

In recent years, intracranial thrombectomy stent has been an important method to treat ischemic stroke caused by acute thrombosis. In this paper, a new intracranial thrombectomy stent with a fish scale-like structure was designed and its mechanical properties were studied by a finite element method. The porosity of all stents was more than 80%. The space occupation ratio (SOR) of the stents increased linearly with the increase of strut thickness, while the strut width had little effect on SOR. The maximum equivalent stress and strain, the directional deformation and overall radial load of the stent decreased with the increase of strut thickness, however, the strut width has little impact on these parameters. The stents with 0.2 mm strut width and the thickness of 0.15 and 0.20 mm had better radial load performance, and the stent with 0.2 mm strut width and 0.15 mm strut thickness had better contact performance with the vessel wall and displayed better flexibility. Therefore, the present study provides a theoretical basis for the design of new intracranial thrombectomy stent.

Type
Article
Copyright
Copyright © Materials Research Society 2020

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Footnotes

c)

These authors contributed equally to this work and should be considered co-first authors.

References

Jiang, J., Wang, Y., Liu, B., Chen, X., and Zhang, S.: Challenges and research progress of the use of mesenchymal stem cells in the treatment of ischemic stroke. Brain Dev. 40, 612626 (2018).10.1016/j.braindev.2018.03.015CrossRefGoogle ScholarPubMed
Howard, R.: The management of ischaemic stroke. Anaesth. Intens. Care Med. 17, 591595 (2016).10.1016/j.mpaic.2016.09.009CrossRefGoogle Scholar
Bussmann, M.L., Neunzig, H.P., Gerber, J., Steinmetz, J., Jung, S., and Deck, R.: Effects and quality of stroke rehabilitation of BAR phase D. Neurol. Int. Open 2, E16E24 (2018).Google Scholar
Zerna, C., Hegedus, J., and Hill, M.D.: Evolving treatments for acute ischemic stroke. Circ. Res. 118, 14251442 (2016).10.1161/CIRCRESAHA.116.307005CrossRefGoogle ScholarPubMed
Alberts, M.J., Shang, T., and Magadan, A.: Endovascular therapy for acute ischemic stroke. JAMA Neurol. 72, 11011103 (2015).10.1001/jamaneurol.2015.1743CrossRefGoogle ScholarPubMed
Pagola, J., Molina, C., Ribo, M., Wijman, C., and Schonewille, W.: Recanalization and outcome after intravenous thrombolysis in acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): Does location of occlusion matter? Stroke 41, e332 (2014).Google Scholar
Janssen, H., Brückmann, H., Killer, M., Heck, S., Buchholz, G., and Lutz, J.: Acute basilar thrombosis: Recanalization following intravenous thrombolysis is dependent on thrombus length. PLoS ONE 13, e0193051 (2018).10.1371/journal.pone.0193051CrossRefGoogle ScholarPubMed
Saver, J.L., Goyal, M., Bonafe, A., Diener, H.C., Levy, E.I., Pereira, V.M., Albers, G.W., Cognard, C., Cohen, D.J., Hacke, W., Jansen, O., Jovin, T.G., Mattle, H.P., Nogueira, R.G., Siddiqui, A.H., Yavagal, D.R., Baxter, B.W., Devlin, T.G., Lopes, D.K., Reddy, V.K., de Rochemont, R.M., Singer, O.C., and Jahan, R.: Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N. Engl. J. Med. 372, 22852295 (2015).10.1056/NEJMoa1415061CrossRefGoogle ScholarPubMed
Ramana, A., Zerna, C., Menon, B.K., and Goyal, M.: Endovascular interventions in acute ischemic stroke: Recent evidence, current challenges, and future prospects. Curr. Atheroscler. Rep. 18, 40 (2016).Google Scholar
Futch, H.S., Corliss, B.M., Polifka, A.J., Holt, B.L., and Fox, W.C.: Solitaire stent retriever mechanical thrombectomy in a 6-month-old patient with acute occlusion of the internal carotid artery terminus: Case report. World Neurosurg. 126, 631637 (2019).10.1016/j.wneu.2019.03.038CrossRefGoogle Scholar
Soize, S., Kadziolka, K., Estrade, L., Serre, I., Bakchine, S., and Pierot, L.: Mechanical thrombectomy in acute stroke: Prospective pilot trial of the Solitaire FR device while under conscious sedation. Am. J. Neuroradiol. 34, 360365 (2013).10.3174/ajnr.A3200CrossRefGoogle ScholarPubMed
Kulcsar, Z., Bonvin, C., Lovblad, K.O., Gory, B., Yilmaz, H., Sztajzel, R., and Rufenacht, D.: Use of the Enterprise™ intracranial stent for revascularization of large vessel occlusions in acute stroke. Clin. Neuroradiol. 20, 5460 (2010).CrossRefGoogle ScholarPubMed
Ding, D., Raper, D.M., Carswell, A.J., and Liu, K.C.: Endovascular stenting for treatment of mycotic intracranial aneurysms. J. Clin. Neurosci. 21, 11631168 (2014).CrossRefGoogle ScholarPubMed
Zhou, L., Ren, Y. and Liang, H.: Clinical analysis of 8 cases of acute ischemic stroke treated with TREVO stent thrombectomy. J. Clin. Res. 34, 533536 (2017).Google Scholar
Summers, A.P.: Fast fish. Nature 429, 3133 (2004).10.1038/429031aCrossRefGoogle ScholarPubMed
Yang, W., Chen, I.H., Gludovatz, B., Zimmermann, E.A., Ritchie, R.O., and Meyers, M.A.: Natural flexible dermal armor. Adv. Mater. 25, 3148 (2013).10.1002/adma.201202713CrossRefGoogle ScholarPubMed
Tang, A.Y.S., Chan, H.N., Tsang, A.C.O., Leung, G.K.K., Leung, K.M., Yu, A.C.H., and Chow, K.W.: The effects of stent porosity on the endovascular treatment of intracranial aneurysms located near a bifurcation. J. Biomed. Sci. Eng. 6, 812822 (2013).10.4236/jbise.2013.68099CrossRefGoogle Scholar
García, A., Peña, E. and Martínez, M.A.: Influence of geometrical parameters on radial force during self-expanding stent deployment. Application for a variable radial stiffness stent. J. Mech. Behav. Biomed. Mater. 10, 166175 (2012).10.1016/j.jmbbm.2012.02.006CrossRefGoogle ScholarPubMed
Qiao, A. and Zeng, K.: Numerical simulation of hemodynamics in intracranial saccular aneurysm treated with a novel stent. Neurol. Res. 35, 701708 (2013).CrossRefGoogle ScholarPubMed
Chuang, Y.C. and Fung, Y.C.: Compressibility and constitutive equation of arterial-wall in radial compression experiments. J. Biomech. 17, 3540 (1984).10.1016/0021-9290(84)90077-0CrossRefGoogle Scholar