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Effect of an organotin catalyst on the physicochemical properties and biocompatibility of castor oil-based polyurethane/cellulose composites

Published online by Cambridge University Press:  23 August 2018

Santiago Villegas-Villalobos ,
Luis E. Díaz ,
Guillermo Vilariño-Feltrer ,
Ana Vallés-Lluch ,
José A. Gómez-Tejedor  and
Manuel F. Valero
Santiago Villegas-Villalobos
Affiliation:
Master in Process Design and Management, Research Group on Energy, Materials and Environment, Faculty of Engineering, Universidad de La Sabana, Chía 140013, Colombia
Luis E. Díaz
Affiliation:
Bioprospecting Research Group, Universidad de La Sabana, Chía 140013, Colombia
Guillermo Vilariño-Feltrer
Affiliation:
Centre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, Valencia 46022, Spain
Ana Vallés-Lluch
Affiliation:
Centre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, Valencia 46022, Spain; and Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Valencia 46022, Spain
José A. Gómez-Tejedor
Affiliation:
Centre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, Valencia 46022, Spain; and Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Valencia 46022, Spain
Manuel F. Valero*
Affiliation:
Research Group on Energy, Materials and Environment, Faculty of Engineering, Universidad de La Sabana, Chía 140013, Colombia
*
a)Address all correspondence to this author. e-mail: [email protected]
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Abstract

Polyurethane/cellulose composites were synthesized from castor-oil-derived polyols and isophorone diisocyanate using dibutyltin dilaurate (DBTDL) as the catalyst. Materials were obtained by adding 2% cellulose in the form of either microcrystals (20 μm) or nanocrystals obtained by acid hydrolysis. The aim was to assess the effects of filler particle size and the use of a catalyst on the physicochemical properties and biological response of these composites. The addition of the catalyst was found to be essential to prevent filler aggregations and to enhance the tensile strength and elongation at break. The cellulose particle size influenced the composite properties, as its nanocrystals heighten hydrogen bond interactions between the filler surface and polyurethane domains, improving resistance to hydrolytic degradation. All hybrids retained cell viability, and the addition of DBTDL did not impair their biocompatibility. The samples were prone to calcification, which suggests that they could find application in the development of bioactive materials.

Keywords

polymercompositeorganometallic-catalyst
Type
Article
Information
Journal of Materials Research , Volume 33 , Issue 17 , 14 September 2018 , pp. 2598 - 2611
Copyright
Copyright © Materials Research Society 2018 

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