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Cytotoxicity and antibacterial efficacy of silver deposited onto titanium plates by low-energy ion implantation

Published online by Cambridge University Press:  12 July 2018

Tatiana P. Soares ,
Charlene S.C. Garcia ,
Mariana Roesch-Ely ,
Marcelo E.H. Maia da Costa ,
Marcelo Giovanela  and
Cesar Aguzzoli Open the ORCID record for Cesar Aguzzoli [Opens in a new window]
Tatiana P. Soares
Affiliation:
Área do Conhecimento de Ciências Exatas e Engenharias, Universidade de Caxias do Sul, Caxias do Sul, RS 95070-560, Brazil
Charlene S.C. Garcia
Affiliation:
Instituto de Biotecnologia, Universidade de Caxias do Sul, Caxias do Sul, RS 95070-560, Brazil
Mariana Roesch-Ely
Affiliation:
Instituto de Biotecnologia, Universidade de Caxias do Sul, Caxias do Sul, RS 95070-560, Brazil
Marcelo E.H. Maia da Costa
Affiliation:
Departamento de Física, Pontifícia Universidade Católica, Rio de Janeiro, RJ 22453-900, Brazil
Marcelo Giovanela
Affiliation:
Área do Conhecimento de Ciências Exatas e Engenharias, Universidade de Caxias do Sul, Caxias do Sul, RS 95070-560, Brazil
Cesar Aguzzoli*
Affiliation:
Área do Conhecimento de Ciências Exatas e Engenharias, Universidade de Caxias do Sul, Caxias do Sul, RS 95070-560, Brazil
*
a)Address all correspondence to this author. e-mail: [email protected]
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Abstract

Contamination by bacterial biofilms has a strong negative impact, especially on the surface of prostheses, implants, pins, and other medical-surgical devices. To prevent their formation, one of the alternatives is the modification of the metal surface incorporating silver by low-energy ion implantation, thus avoiding initial bacteria adhesion to the modified surface and further development of the biofilm. The bactericidal properties of silver atoms incorporated on commercially pure titanium surfaces by low-energy ion implantation (4 keV) were evaluated. The surface modifications were analyzed by Rutherford backscattering spectrometry, glow discharge-optical emission spectroscopy, contact angle measure, optical profilometry, and X-ray photoelectron spectroscopy. The microbiological assays were conducted by using Escherichia coli (E. coli). The results demonstrated a reduction on bacterial counting. No toxic effect of silver was detected on human MG-63 cells. The choice of parameters to obtain a bactericidal and nontoxic biomaterial for human cells should consider the ideal combination “energy + silver concentration”. Therefore, it can be considered for industrial application.

Keywords

low energy ion implantationsilvertitaniumantibacterial properties
Type
REVIEW
Information
Journal of Materials Research , Volume 33 , Issue 17 , 14 September 2018 , pp. 2545 - 2553
Copyright
Copyright © Materials Research Society 2018 

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Footnotes

This section of Journal of Materials Research is reserved for papers that are reviews of literature in a given area.

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