Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-30T17:50:06.770Z Has data issue: false hasContentIssue false
  • English
  • Français

How Clinical Trial Data Sharing Platforms Can Advance the Study of Biomarkers

Published online by Cambridge University Press:  01 January 2021

Rebecca Li  and
Ida Sim
Get access Rights & Permissions [Opens in a new window]

Abstract

Although data sharing platforms host diverse data types the features of these platforms are well-suited to facilitating biomarker research. Given the current state of biomarker discovery, an innovative paradigm to accelerate biomarker discovery is to utilize platforms such as Vivli to leverage researchers' abilities to integrate certain classes of biomarkers.

Type
Symposium Articles
Information
Journal of Law, Medicine & Ethics , Volume 47 , Issue 3: Biomarker Research and Validation: Current Challenges, Future Opportunities , Fall 2019 , pp. 369 - 373
Copyright
Copyright © American Society of Law, Medicine and Ethics 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bauchner, H. et al., “Data Sharing: An Ethical and Scientific Imperative,” JAMA 315, no. 12 (2016): 1238–1240.CrossRefGoogle Scholar
Mello, M., et al., “Preparing for Responsible Sharing of Clinical Trial Data,” New England Journal of Medicine 369, no. 17 (2013): 1651-1658; see <https://nam.edu/moving-data-shar-ing-forward-the-launch-of-the-vivli-platform/> (last visited July 8, 2019).CrossRefGoogle Scholar
Institute of Medicine, Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk (Washington, DC: The National Academies Press, 2015), available at <http://dx.doi.org/https://doi.org/10.17226/18998> (last visited July 8, 2019).+(last+visited+July+8,+2019).>Google Scholar
Bierer, B. E., et al., “A Global, Neutral Platform for Sharing Trial Data,” New England Journal of Medicine 374, no. 25 (2016): 2411-2413.CrossRefGoogle Scholar
Rockhold, F., Nisen, P., and Freeman, A., “Data Sharing at a Crossroads,” New England Journal of Medicine 375, no. 12 (2016): 1115-1117.CrossRefGoogle Scholar
Ross, J. S., et al., “Overview and Experience of the YODA Project with Clinical Trial Data Sharing after 5 years,” Scientific Data 5 (2018): article number 180268.CrossRefGoogle Scholar
Zarin, D. A. and Tse, T., “Sharing Individual Participant Data (IPD) Within the Context of the Trial Reporting System (TRS),” PLoS Medicine 13, no. 1 (2016): e1001946.CrossRefGoogle Scholar
Debray, T. P. A., Moons, K. G. M., van Valkenhoef, G., et al., “Get Real in Individual Participant Data (IPD) Meta-Analysis: A Review of the Methodology,” Research Synthesis Methods 6, no. 4 (2015): 293–309.CrossRefGoogle Scholar
Nevitt, S. J., et al., “Exploring Changes Over Time and Characteristics Associated with Data Retrieval Across Individual Participant Data Meta-Analyses: A Systematic Review,” BMJ 357 (2017): j1390.CrossRefGoogle Scholar
See <https://www.nlm.nih.gov/cde/> (last visited July 8, 2019).+(last+visited+July+8,+2019).>Google Scholar
Bakkar, N., Boehringer, A., and Bowser, R., “Use of Biomarkers in ALS Drug Development and Clinical Trials,” Brain Research 1607 (2015): 94–107.CrossRefGoogle Scholar
Sledge, J. G., Miller, R. S., and Hauser, R., “CancerLinQ and the Future of Cancer Care,” American Society of Clinical Oncology Educational Book (2013): 430-434.CrossRefGoogle Scholar
American Society of Clinical Oncology, Annual Meeting, American Society of Clinical Oncology Educational Book, 430-434; Green, K, et al., “The Project Data Sphere Initiative: Accelerating Cancer Research by Sharing Data,” Oncologist 20, no. 5 (2015): 464-e20, doi: http://dx.doi.org/10.1634/theoncologist.2014-0431.CrossRefGoogle Scholar