Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-04T19:01:17.911Z Has data issue: false hasContentIssue false
  • English
  • Français

Wegener's granulomatosis in two siblings: a family study

Published online by Cambridge University Press:  29 June 2007

P. J. Stoney ,
W. Davies ,
S. F. Ho ,
I. C. Paterson  and
I. P. Griffith
P. J. Stoney*
Affiliation:
Departments of Otolaryngology, University Hospital of Wales.
W. Davies
Affiliation:
Radiotherapy and Oncology, University Hospital of Wales.
S. F. Ho
Affiliation:
Departments of Otolaryngology, University Hospital of Wales.
I. C. Paterson
Affiliation:
Radiotherapy and Oncology, University Hospital of Wales.
I. P. Griffith
Affiliation:
Departments of Otolaryngology, University Hospital of Wales.
*
Mr P. J.Stoney, Senior Registrar in Otolarygology, University Hospital of Wales, Heath Park, Cardiff CF44XW.
Get access Rights & Permissions [Opens in a new window]

Abstract

Two brothers with Wegener's granulomatosis are presented. HLA status and associated genes in the brothers and the immediate family are explored. No specific association could be found with tissue types within the family.

Keywords

Wegener's granulomatosis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 2 , February 1991 , pp. 123 - 124
Copyright
Copyright © JLO (1984) Limited 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Beigel, A., Lehmann, H., Westphal, E. (1981) Histokompatibilitatsmuster (HLA-antigene) bei Wegenerscher granulomatose. Archives of Oto-rhino-laryngology, 233: 157–160.CrossRefGoogle Scholar
Bradley, P. J. (1983) Wegeners granulomatosis of the ear. Journal of Laryngology and Otology, 97: 623–626.CrossRefGoogle ScholarPubMed
Coutu, R. E., Klein, M.Lessell, S., Friedman, E., Snider, G. L. (1975) Limited form of Wegeners granulomatosis: eye involvement as a major sign. Journal of the American Medical Association, 233: 868–871.CrossRefGoogle ScholarPubMed
Elkon, K. B., Sutherland, D. C.Rees, A. J., Hughes, G. R. V., Batchelor, J. R. (1983) HLA antigen frequencies in systemic vasculitis: increase in HLA-DR2 in Wegener's granulomatosis. Arthritis and Rheumatism, 26: 102–105.CrossRefGoogle ScholarPubMed
Fauci, A. S., Haynes, B. F., Katz, P., Wolff, S. M. (1983) Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Annals of Internal Medicine, 98: 76–85.CrossRefGoogle Scholar
Hoare, T. J., Jayne, D., Rhys Evans, P., Croft, C. B., Howard, D. J. (1989) Wegeners granulomatosis, subglottic stenosis and antineutrophil cytoplasm antibodies. Journal of Laryngology and Otology, 103:1187–1191.CrossRefGoogle ScholarPubMed
Katz, P., Ailing, D. W., Haynes, B. F., Fauci, A. S. (1979) Association of Wegener's granulomatosis with HLA-B8. Clinical Immunology and Immunopathology, 14:268–270.CrossRefGoogle ScholarPubMed
Kempf, H. G. (1989) Ear involvement in Wegeners granulomatosis. Clinical Otolaryngology, 14:451–456.Google Scholar
Kornblut, A. D., Wolff, S. M., Fauci, A. S. (1982) Ear disease in patients with Wegeners granulomatosis. Laryngoscope, 92: 713–717.CrossRefGoogle Scholar
Lockwood, M. Personal communication.Google Scholar
Mains, B. (1989) Wegener's granulomatosis: false positive anti-neutrophil cytoplasmic antibody test. Journal of Laryngology and Otology, 103:524–525.Google ScholarPubMed
Muniain, M. A., Moreno, J. C., Campora, R. G. (1986) Wegener's granulomatosis in two sisters. Annals of the Rheumatic Diseases, 45:417–421.CrossRefGoogle ScholarPubMed
Noelle, B., Specks, U., Luedemann, J., Rohrbach, M. S., DeRemee, R. A., Gross, W. L. (1989) Anticytoplasmic antibodies: their immunodiagnostic value in Wegeners granulomatosis. Annals of Internal Medicine, 111: 28–40.CrossRefGoogle Scholar
Ridley, M. G., Wolfe, C. S., Asherson, R. A., Hughes, G. R. V. (1988) Recurrent otitis media and pulmonary infiltrates as presenting features in Wegeners granulomatosis. British Medical Journal, 297: 352–353.CrossRefGoogle Scholar
Spalton, D. J., Graham, E. M., Page, N. G. R., Sanders, M. D. (1981) Ocular changes in limited forms of Wegeners granulomatosis. British Journal of Ophthalmology, 65: 553–563.CrossRefGoogle Scholar
Strimlan, C. V., Taswell, H. F., Kueppers, F., DeRemee, R. A., McDonald, T. J. (1978) HL-A antigens of patients with Wegeners granulomatosis. Tissue Antigens, 11: 129–131.CrossRefGoogle Scholar
Walton, E. W. (1958) Giant-cell granuloma of the respiratory tract (Wegeners granulomatosis). British Medical Journal, 2:265–270.CrossRefGoogle Scholar
Wegener, F. (1936) Ubcr generalisierte septische Gefasserkrankungen. Verhandlungen des Deutschen Pthologischen Gesellschaft Ges, 29: 202–209.Google Scholar
Wegener, F. (1990) Wegeners granulomatosis. Thoughts and observations of a pathologist. European Archives of Otorhinolaryngology, 247:133–142.Google ScholarPubMed